3FDL
Bim BH3 peptide in complex with Bcl-xL
Summary for 3FDL
Entry DOI | 10.2210/pdb3fdl/pdb |
Related | 3FDM |
Descriptor | Apoptosis regulator Bcl-X, Bcl-2-like protein 11 (3 entities in total) |
Functional Keywords | helical bundle, peptide-protein complex, apoptosis, alternative splicing, membrane, mitochondrion, nucleus, transmembrane, phosphoprotein |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817 Endomembrane system ; Peripheral membrane protein . Isoform BimEL: Mitochondrion. Isoform BimL: Mitochondrion. Isoform BimS: Mitochondrion. Isoform Bim-alpha1: Mitochondrion: O43521 |
Total number of polymer chains | 2 |
Total formula weight | 21192.65 |
Authors | Fairlie, W.D.,Lee, E.F.,Smith, B.J.,Czabotar, P.E.,Colman, P.M. (deposition date: 2008-11-26, release date: 2009-03-10, Last modification date: 2023-11-01) |
Primary citation | Lee, E.F.,Sadowsky, J.D.,Smith, B.J.,Czabotar, P.E.,Peterson-Kaufman, K.J.,Colman, P.M.,Gellman, S.H.,Fairlie, W.D. High-Resolution Structural Characterization of a Helical alpha/beta-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-x(L) Angew.Chem.Int.Ed.Engl., 48:4318-4322, 2009 Cited by PubMed: 19229915DOI: 10.1002/anie.200805761 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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