5J3H
Human insulin receptor domains L1-CR in complex with peptide S519C16 and 83-7 Fv
Summary for 5J3H
| Entry DOI | 10.2210/pdb5j3h/pdb |
| Descriptor | Peptide S519C16, mAb 83-7 Fab heavy chain, mAb 83-7 Fab light chain, ... (8 entities in total) |
| Functional Keywords | insulin receptor insulin mimetic peptide fv fragment, hormone receptor-immune system complex, hormone receptor/immune system |
| Biological source | Mus musculus More |
| Total number of polymer chains | 4 |
| Total formula weight | 67472.10 |
| Authors | Lawrence, M.,Menting, J.,Lawrence, C. (deposition date: 2016-03-30, release date: 2016-06-15, Last modification date: 2023-09-27) |
| Primary citation | Lawrence, C.F.,Margetts, M.B.,Menting, J.G.,Smith, N.A.,Smith, B.J.,Ward, C.W.,Lawrence, M.C. Insulin Mimetic Peptide Disrupts the Primary Binding Site of the Insulin Receptor. J.Biol.Chem., 291:15473-15481, 2016 Cited by PubMed: 27281820DOI: 10.1074/jbc.M116.732180 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.27 Å) |
Structure validation
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