3D06
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![BU of 3d06 by Molmil](/molmil-images/mine/3d06) | Human p53 core domain with hot spot mutation R249S (I) | Descriptor: | Cellular tumor antigen p53, ZINC ION | Authors: | Rozenberg, H, Suad, O, Shimon, L.J.W, Frolow, F, Shakked, Z. | Deposit date: | 2008-05-01 | Release date: | 2009-01-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations J.Mol.Biol., 385, 2009
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3D05
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![BU of 3d05 by Molmil](/molmil-images/mine/3d05) | Human p53 core domain with hot spot mutation R249S (II) | Descriptor: | Cellular tumor antigen p53, ZINC ION | Authors: | Suad, O, Rozenberg, H, Shimon, L.J.W, Frolow, F, Shakked, Z. | Deposit date: | 2008-05-01 | Release date: | 2009-01-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations J.Mol.Biol., 385, 2009
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2ATB
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![BU of 2atb by Molmil](/molmil-images/mine/2atb) | Triple mutant 8D9D10V of scorpion toxin LQH-alpha-IT | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, NITRATE ION, ... | Authors: | Kahn, R, Karbat, I, Gurevitz, M, Frolow, F. | Deposit date: | 2005-08-24 | Release date: | 2006-09-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant To be Published
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2ASC
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![BU of 2asc by Molmil](/molmil-images/mine/2asc) | Scorpion toxin LQH-alpha-IT | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, ETHANOL, ... | Authors: | Kahn, R, Karbat, I, Gurevitz, M, Frolow, F. | Deposit date: | 2005-08-23 | Release date: | 2006-09-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant To be Published
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2D94
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![BU of 2d94 by Molmil](/molmil-images/mine/2d94) | THE CONFORMATION OF THE DNA DOUBLE HELIX IN THE CRYSTAL IS DEPENDENT ON ITS ENVIRONMENT | Descriptor: | DNA (5'-D(*GP*GP*GP*CP*GP*CP*CP*C)-3') | Authors: | Shakked, Z, Guerstein-Guzikevich, G, Eisenstein, M, Frolow, F, Rabinovich, D. | Deposit date: | 1993-07-13 | Release date: | 1994-01-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The conformation of the DNA double helix in the crystal is dependent on its environment. Nature, 342, 1989
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1MSD
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![BU of 1msd by Molmil](/molmil-images/mine/1msd) | COMPARISON OF THE CRYSTAL STRUCTURES OF GENETICALLY ENGINEERED HUMAN MANGANESE SUPEROXIDE DISMUTASE AND MANGANESE SUPEROXIDE DISMUTASE FROM THERMUS THERMOPHILUS. DIFFERENCES IN DIMER-DIMER INTERACTIONS. | Descriptor: | MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE | Authors: | Sussman, J, Wagner, U.G, Pattridge, K.A, Ludwig, M.L. | Deposit date: | 1992-11-10 | Release date: | 1993-07-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Comparison of the crystal structures of genetically engineered human manganese superoxide dismutase and manganese superoxide dismutase from Thermus thermophilus: differences in dimer-dimer interaction. Protein Sci., 2, 1993
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8GCH
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![BU of 8gch by Molmil](/molmil-images/mine/8gch) | |
1GCD
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![BU of 1gcd by Molmil](/molmil-images/mine/1gcd) | |
1GMH
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![BU of 1gmh by Molmil](/molmil-images/mine/1gmh) | |
4VGC
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![BU of 4vgc by Molmil](/molmil-images/mine/4vgc) | GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | Descriptor: | D-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID, GAMMA CHYMOTRYPSIN, SULFATE ION | Authors: | Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. | Deposit date: | 1997-05-01 | Release date: | 1997-11-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. Biochemistry, 37, 1998
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1AX9
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![BU of 1ax9 by Molmil](/molmil-images/mine/1ax9) | ACETYLCHOLINESTERASE COMPLEXED WITH EDROPHONIUM, LAUE DATA | Descriptor: | ACETYLCHOLINESTERASE, EDROPHONIUM ION | Authors: | Raves, M.L, Ravelli, R.B.G, Sussman, J.L, Harel, M, Silman, I. | Deposit date: | 1997-11-03 | Release date: | 1998-02-11 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Static Laue diffraction studies on acetylcholinesterase. Acta Crystallogr.,Sect.D, 54, 1998
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1EA5
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![BU of 1ea5 by Molmil](/molmil-images/mine/1ea5) | NATIVE ACETYLCHOLINESTERASE (E.C. 3.1.1.7) FROM TORPEDO CALIFORNICA at 1.8A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE | Authors: | Harel, M, Weik, M, Silman, I, Sussman, J.L. | Deposit date: | 2000-11-06 | Release date: | 2000-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-Ray Structures of Torpedo Californica Acetylcholinesterase Complexed with (+)-Huperzine a and (-)-Huperzine B: Structural Evidence for an Active Site Rearrangement Biochemistry, 41, 2002
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6QDI
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![BU of 6qdi by Molmil](/molmil-images/mine/6qdi) | anti-sigma factor domain-containing protein from Clostridium clariflavum | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, PA14 domain-containing protein | Authors: | Voronov, M, Bayer, E.A, Livnah, O. | Deposit date: | 2019-01-01 | Release date: | 2019-06-12 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Distinctive ligand-binding specificities of tandem PA14 biomass-sensory elements from Clostridium thermocellum and Clostridium clariflavum. Proteins, 87, 2019
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6QE7
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![BU of 6qe7 by Molmil](/molmil-images/mine/6qe7) | anti-sigma factor domain-containing protein | Descriptor: | Anti-sigma-I factor RsgI3, CALCIUM ION | Authors: | Voronov, M, Livnah, O, Bayer, E.A. | Deposit date: | 2019-01-07 | Release date: | 2019-06-12 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Distinctive ligand-binding specificities of tandem PA14 biomass-sensory elements from Clostridium thermocellum and Clostridium clariflavum. Proteins, 87, 2019
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1ACL
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![BU of 1acl by Molmil](/molmil-images/mine/1acl) | |
1ACJ
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2ACE
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![BU of 2ace by Molmil](/molmil-images/mine/2ace) | NATIVE ACETYLCHOLINESTERASE (E.C. 3.1.1.7) FROM TORPEDO CALIFORNICA | Descriptor: | ACETYLCHOLINE, ACETYLCHOLINESTERASE | Authors: | Harel, M, Raves, M.L, Silman, I, Sussman, J.L. | Deposit date: | 1996-06-23 | Release date: | 1996-11-08 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A. Nat.Struct.Biol., 4, 1997
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2ACK
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![BU of 2ack by Molmil](/molmil-images/mine/2ack) | ACETYLCHOLINESTERASE COMPLEXED WITH EDROPHONIUM, MONOCHROMATIC DATA | Descriptor: | ACETYLCHOLINESTERASE, EDROPHONIUM ION | Authors: | Raves, M.L, Sussman, J.L, Harel, M, Silman, I. | Deposit date: | 1997-10-29 | Release date: | 1998-02-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Static Laue diffraction studies on acetylcholinesterase. Acta Crystallogr.,Sect.D, 54, 1998
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3FPL
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![BU of 3fpl by Molmil](/molmil-images/mine/3fpl) | Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of C. beijerinckii ADH by T. brockii ADH | Descriptor: | 1,2-ETHANEDIOL, CACODYLATE ION, CHLORIDE ION, ... | Authors: | Felix, F, Goihberg, E, Shimon, L, Burstein, Y. | Deposit date: | 2009-01-05 | Release date: | 2010-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms Biochemistry, 49, 2010
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3FPC
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![BU of 3fpc by Molmil](/molmil-images/mine/3fpc) | Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-294 of T. brockii ADH by E. histolytica ADH | Descriptor: | 1,2-ETHANEDIOL, CACODYLATE ION, IMIDAZOLE, ... | Authors: | Felix, F, Goihberg, E, Shimon, L, Burstein, Y. | Deposit date: | 2009-01-05 | Release date: | 2010-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms Biochemistry, 49, 2010
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6YHT
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![BU of 6yht by Molmil](/molmil-images/mine/6yht) | A lid blocking mechanism of a cone snail toxin revealed at the atomic level | Descriptor: | CITRIC ACID, Conk-C1, SULFATE ION | Authors: | Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I. | Deposit date: | 2020-03-31 | Release date: | 2021-04-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A Molecular Lid Mechanism of K + Channel Blocker Action Revealed by a Cone Peptide. J.Mol.Biol., 433, 2021
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6YHY
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![BU of 6yhy by Molmil](/molmil-images/mine/6yhy) | A lid blocking mechanism of a cone snail toxin revealed at the atomic level | Descriptor: | Conk-S1 | Authors: | Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I. | Deposit date: | 2020-03-31 | Release date: | 2021-04-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A Molecular Lid Mechanism of K + Channel Blocker Action Revealed by a Cone Peptide. J.Mol.Biol., 433, 2021
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1JVB
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![BU of 1jvb by Molmil](/molmil-images/mine/1jvb) | ALCOHOL DEHYDROGENASE FROM THE ARCHAEON SULFOLOBUS SOLFATARICUS | Descriptor: | NAD(H)-DEPENDENT ALCOHOL DEHYDROGENASE, ZINC ION | Authors: | Esposito, L, Sica, F, Zagari, A, Mazzarella, L. | Deposit date: | 2001-08-29 | Release date: | 2002-08-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of the alcohol dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus at 1.85 A resolution. J.Mol.Biol., 318, 2002
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2VGC
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![BU of 2vgc by Molmil](/molmil-images/mine/2vgc) | GAMMA-CHYMOTRYPSIN D-PARA-CHLORO-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | Descriptor: | D-1-(4-CHLOROPHENYL)-2-(ACETAMIDO)ETHANE BORONIC ACID, GAMMA CHYMOTRYPSIN, SULFATE ION | Authors: | Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. | Deposit date: | 1997-05-01 | Release date: | 1997-11-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. Biochemistry, 37, 1998
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3D0A
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![BU of 3d0a by Molmil](/molmil-images/mine/3d0a) | |