8AJJ
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6O15
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![BU of 6o15 by Molmil](/molmil-images/mine/6o15) | Crystal structure of a putative oxidoreductase YjhC from Escherichia coli in complex with NAD(H) | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, Uncharacterized oxidoreductase YjhC | Authors: | Horne, C.R, Kind, L, Davies, J.S, Dobson, R.C. | Deposit date: | 2019-02-17 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism. Proteins, 88, 2020
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8AJK
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![BU of 8ajk by Molmil](/molmil-images/mine/8ajk) | Crystal structure of a C43S variant from the disulfide reductase MerA from Staphylococcus aureus | Descriptor: | FAD-containing oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Weiland, P, Altegoer, F, Bange, G. | Deposit date: | 2022-07-28 | Release date: | 2023-03-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | MerA functions as a hypothiocyanous acid reductase and defense mechanism in Staphylococcus aureus. Mol.Microbiol., 119, 2023
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5E4E
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![BU of 5e4e by Molmil](/molmil-images/mine/5e4e) | Engineered Interleukin-13 bound to receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13, Interleukin-13 receptor subunit alpha-1, ... | Authors: | Moraga, I, Thomas, C, Jude, K.M, Garcia, K.C. | Deposit date: | 2015-10-05 | Release date: | 2015-12-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency. Sci.Signal., 8, 2015
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8EC4
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8EBI
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8ECF
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8EBR
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8BVB
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6B1I
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3VDQ
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![BU of 3vdq by Molmil](/molmil-images/mine/3vdq) | Crystal structure of alcaligenes faecalis D-3-hydroxybutyrate dehydrogenase in complex with NAD(+) and acetate | Descriptor: | ACETATE ION, CALCIUM ION, CHLORIDE ION, ... | Authors: | Hoque, M.M, Shimizu, S, Hossain, M.T, Yamamoto, T, Suzuki, K, Takenaka, A. | Deposit date: | 2012-01-06 | Release date: | 2012-02-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structures of Alcaligenes faecalis D-3-hydroxybutyrate dehydrogenase before and after NAD+ and acetate binding suggest a dynamical reaction mechanism as a member of the SDR family. Acta Crystallogr.,Sect.D, 64, 2008
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6EUD
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6B1M
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6F0E
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![BU of 6f0e by Molmil](/molmil-images/mine/6f0e) | Structure of yeast Sec14p with a picolinamide compound | Descriptor: | SEC14 cytosolic factor, ~{N}-(1,3-benzodioxol-5-ylmethyl)-5-bromanyl-3-fluoranyl-pyridine-2-carboxamide | Authors: | Hong, Z, Johnen, P, Schaaf, G, Bono, F. | Deposit date: | 2017-11-20 | Release date: | 2018-01-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Target Identification and Mechanism of Action of Picolinamide and Benzamide Chemotypes with Antifungal Properties. Cell Chem Biol, 25, 2018
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6CMG
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6CIP
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6CIN
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6B1N
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6CIO
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![BU of 6cio by Molmil](/molmil-images/mine/6cio) | Pyruvate:ferredoxin oxidoreductase from Moorella thermoacetica with lactyl-TPP bound | Descriptor: | 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-CARBOXY-1-HYDROXYETHYL)-5-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | Authors: | Chen, P.Y.-T, Drennan, C.L. | Deposit date: | 2018-02-24 | Release date: | 2018-03-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.003 Å) | Cite: | Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase fromMoorella thermoacetica. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6CMI
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6CIQ
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4A5M
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![BU of 4a5m by Molmil](/molmil-images/mine/4a5m) | Redox regulator HypR in its oxidized form | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR YYBR | Authors: | Palm, G.J, Waack, P, Read, R.J, Hinrichs, W. | Deposit date: | 2011-10-26 | Release date: | 2012-01-11 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Insights Into the Redox-Switch Mechanism of the Marr/Duf24-Type Regulator Hypr Nucleic Acids Res., 40, 2012
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4A5N
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![BU of 4a5n by Molmil](/molmil-images/mine/4a5n) | Redoxregulator HypR in its reduced form | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR YYBR | Authors: | Palm, G.J, Waack, P, Read, R.J, Hinrichs, W. | Deposit date: | 2011-10-26 | Release date: | 2012-01-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structural Insights Into the Redox-Switch Mechanism of the Marr/Duf24-Type Regulator Hypr Nucleic Acids Res., 40, 2012
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7VRM
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![BU of 7vrm by Molmil](/molmil-images/mine/7vrm) | crystal structure of BRD2-BD2 in complex with purine derivative | Descriptor: | Bromodomain-containing protein 2, THEOPHYLLINE | Authors: | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. | Deposit date: | 2021-10-23 | Release date: | 2023-02-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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7VRO
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![BU of 7vro by Molmil](/molmil-images/mine/7vro) | crystal structure of BRD2-BD1 in complex with purine derivative | Descriptor: | Bromodomain-containing protein 2, SULFATE ION, THEOBROMINE | Authors: | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. | Deposit date: | 2021-10-23 | Release date: | 2023-02-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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