6B1N

Disrupted hydrogen bond network impairs ATPase activity in an Hsc70 cysteine mutant

Summary for 6B1N

Entry DOI	10.2210/pdb6b1n/pdb
Descriptor	Heat shock protein family A (Hsp70) member 8, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	hsp70 family member, chaperone, atpase
Biological source	Homo Sapiens
Total number of polymer chains	2
Total formula weight	89817.26
Authors	O'Donnell, J.P. (deposition date: 2017-09-18, release date: 2018-01-17, Last modification date: 2023-10-04)
Primary citation	O'Donnell, J.P.,Marsh, H.M.,Sondermann, H.,Sevier, C.S. Disrupted Hydrogen-Bond Network and Impaired ATPase Activity in an Hsc70 Cysteine Mutant. Biochemistry, 57:1073-1086, 2018 Cited by PubMed: 29300467 DOI: 10.1021/acs.biochem.7b01005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation