6B1M
Disrupted hydrogen bond network impairs ATPase activity in an Hsc70 cysteine mutant
Summary for 6B1M
Entry DOI | 10.2210/pdb6b1m/pdb |
Descriptor | Heat shock protein family A (Hsp70) member 8, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | hsp70 family member, chaperone, atpase |
Biological source | Homo Sapiens |
Total number of polymer chains | 2 |
Total formula weight | 89514.78 |
Authors | O'Donnell, J.P. (deposition date: 2017-09-18, release date: 2018-01-17, Last modification date: 2023-10-04) |
Primary citation | O'Donnell, J.P.,Marsh, H.M.,Sondermann, H.,Sevier, C.S. Disrupted Hydrogen-Bond Network and Impaired ATPase Activity in an Hsc70 Cysteine Mutant. Biochemistry, 57:1073-1086, 2018 Cited by PubMed: 29300467DOI: 10.1021/acs.biochem.7b01005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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