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7D3B
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BU of 7d3b by Molmil
flavone reductase
Descriptor: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, Cd1, FLAVIN MONONUCLEOTIDE
Authors:Hong, S, Yang, G.H, Zhang, P.
Deposit date:2020-09-18
Release date:2021-03-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Discovery of an ene-reductase for initiating flavone and flavonol catabolism in gut bacteria.
Nat Commun, 12, 2021
7D3A
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BU of 7d3a by Molmil
flavone reductase
Descriptor: 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Cd1, FLAVIN MONONUCLEOTIDE
Authors:Hong, S, Yang, G.H, Zhang, P.
Deposit date:2020-09-18
Release date:2021-03-03
Last modified:2021-09-29
Method:X-RAY DIFFRACTION (2.552 Å)
Cite:Discovery of an ene-reductase for initiating flavone and flavonol catabolism in gut bacteria.
Nat Commun, 12, 2021
7DRI
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BU of 7dri by Molmil
Structure of SspE_CTD_41658
Descriptor: DUF1524 domain
Authors:Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G.
Deposit date:2020-12-28
Release date:2022-06-29
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE.
Nat Commun, 13, 2022
7DRS
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BU of 7drs by Molmil
Structure of SspE_40224
Descriptor: SspE protein
Authors:Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G.
Deposit date:2020-12-29
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE.
Nat Commun, 13, 2022
7DRR
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BU of 7drr by Molmil
Structure of SspE-R100A protein
Descriptor: SspE protein
Authors:Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G.
Deposit date:2020-12-29
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.48 Å)
Cite:Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE.
Nat Commun, 13, 2022
7X4E
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BU of 7x4e by Molmil
Structure of 10635-DndE
Descriptor: DNA sulfur modification protein DndE, GLYCEROL
Authors:Haiyan, G, Wei, H, Chen, S, Wang, L, Wu, G.
Deposit date:2022-03-02
Release date:2022-04-20
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural and Functional Analysis of DndE Involved in DNA Phosphorothioation in the Haloalkaliphilic Archaea Natronorubrum bangense JCM10635.
Mbio, 13, 2022
4N0S
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BU of 4n0s by Molmil
Complex of ERK2 with caffeic acid
Descriptor: CAFFEIC ACID, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Kurinov, I, Malakhova, M.
Deposit date:2013-10-02
Release date:2014-08-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7992 Å)
Cite:Caffeic Acid Directly Targets ERK1/2 to Attenuate Solar UV-Induced Skin Carcinogenesis.
Cancer Prev Res (Phila), 7, 2014
8IOY
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BU of 8ioy by Molmil
Structure of ATP7B C983S/C985S/D1027A mutant with AMP-PNP
Descriptor: Copper-transporting ATPase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yang, G, Xu, L, Guo, J, Wu, Z.
Deposit date:2023-03-13
Release date:2023-04-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
7XUK
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BU of 7xuk by Molmil
Structure of ATP7B C983S/C985S/D1027A mutant in presence of ATOX1
Descriptor: Copper-transporting ATPase 2
Authors:Yang, G, Xu, L, Guo, J, Wu, Z.
Deposit date:2022-05-18
Release date:2023-04-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
7XUM
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BU of 7xum by Molmil
Structure of ATP7B C983S/C985S/D1027A mutant with Cu+ in presence of ATOX1
Descriptor: COPPER (II) ION, Copper-transporting ATPase 2
Authors:Yang, G, Xu, L, Chang, S, Guo, J, Wu, Z.
Deposit date:2022-05-19
Release date:2023-05-03
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
7XUN
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BU of 7xun by Molmil
Structure of ATP7B C983S/C985S/D1027A mutant
Descriptor: Copper-transporting ATPase 2
Authors:Yang, G, Xu, L, Guo, J, Wu, Z.
Deposit date:2022-05-19
Release date:2023-04-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
7XUO
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BU of 7xuo by Molmil
Structure of ATP7B C983S/C985S/D1027A mutant with cisplatin in presence of ATOX1
Descriptor: Copper-transporting ATPase 2, PLATINUM (II) ION
Authors:Yang, G, Xu, L, Chang, S, Guo, J, Wu, Z.
Deposit date:2022-05-19
Release date:2023-04-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
4RAK
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BU of 4rak by Molmil
Crystal structure of nuclear receptor subfamily 1, group h, member 2 (lxrb) complexed with partial agonist
Descriptor: 1,4-BUTANEDIOL, 2-{2-[2-(2-chlorophenyl)propan-2-yl]-1-[3'-(methylsulfonyl)biphenyl-4-yl]-1H-imidazol-4-yl}propan-2-ol, Oxysterols receptor LXR-beta
Authors:Nanao, M.
Deposit date:2014-09-10
Release date:2014-12-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Liver X Receptor (LXR) partial agonists: Biaryl pyrazoles and imidazoles displaying a preference for LXR beta.
Bioorg.Med.Chem.Lett., 25, 2015
5XLS
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BU of 5xls by Molmil
Crystal structure of UraA in occluded conformation
Descriptor: 12-TUNGSTOPHOSPHATE, URACIL, Uracil permease
Authors:Yu, X.Z, Yang, G.H, Yan, C.Y, Yan, N.
Deposit date:2017-05-11
Release date:2017-07-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters
Cell Res., 27, 2017
5FA5
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BU of 5fa5 by Molmil
Crystal Structure of PRMT5:MEP50 in complex with MTA and H4 peptide
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Histone H4, Methylosome protein 50, ...
Authors:Sprague, E.R, McNamara, J.T.
Deposit date:2015-12-10
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5.
Science, 351, 2016
8X7X
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BU of 8x7x by Molmil
Crystal structure of SADS-CoV fusion core
Descriptor: CHLORIDE ION, HR1, HR2
Authors:Yan, L.
Deposit date:2023-11-26
Release date:2024-02-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal Structures of Fusion Cores from CCoV-HuPn-2018 and SADS-CoV.
Viruses, 16, 2024
7CWO
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BU of 7cwo by Molmil
SARS-CoV-2 spike protein RBD and P17 fab complex
Descriptor: Spike glycoprotein, heavy chain of P17 Fab, light chain of P17 Fab
Authors:Wang, X, Wang, N.
Deposit date:2020-08-29
Release date:2020-12-16
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
7CWL
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BU of 7cwl by Molmil
SARS-CoV-2 spike protein and P17 fab complex with one RBD in close state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab P17 heavy chain, Fab P17 light chain, ...
Authors:Wang, X, Wang, N.
Deposit date:2020-08-29
Release date:2021-01-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
7CWM
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BU of 7cwm by Molmil
Complex of SARS-CoV-2 spike protein and Fab P17 with one RBD in open state and two RBD in closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P17 heavy chain, ...
Authors:Wang, N, Wang, X.
Deposit date:2020-08-29
Release date:2020-12-16
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
7CWN
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BU of 7cwn by Molmil
P17-H014 Fab cocktail in complex with SARS-CoV-2 spike protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Wang, N, Wang, X.
Deposit date:2020-08-29
Release date:2020-12-16
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
6KVA
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BU of 6kva by Molmil
Structure of anti-hCXCR2 abN48-2 in complex with its CXCR2 epitope
Descriptor: 1,2-ETHANEDIOL, Peptide from C-X-C chemokine receptor type 2, heavy chain, ...
Authors:Xiang, J.C, Yan, L, Yang, B, Wilson, I.A.
Deposit date:2019-09-03
Release date:2020-09-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.
Nat Commun, 12, 2021
6KVF
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BU of 6kvf by Molmil
Structure of anti-hCXCR2 abN48 in complex with its CXCR2 epitope
Descriptor: Peptide from C-X-C chemokine receptor type 2, heavy chain, light chain
Authors:Xiang, J.C, Yan, L, Yang, B, Wilson, I.A.
Deposit date:2019-09-04
Release date:2020-09-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.
Nat Commun, 12, 2021
6JYZ
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BU of 6jyz by Molmil
Crystal structure of endogalactoceramidase
Descriptor: 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ISOPROPYL ALCOHOL, ...
Authors:Liuqing, C, Yan, F.
Deposit date:2019-04-29
Release date:2019-10-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of an endogalactosylceramidase from Rhodococcus hoagii 103S reveals the molecular basis of its substrate specificity.
J.Struct.Biol., 208, 2019
5ZT3
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BU of 5zt3 by Molmil
Crystal structure of WA352 from Oryza sativa
Descriptor: WA352
Authors:Wang, X, Guan, Z, Yin, P.
Deposit date:2018-05-01
Release date:2018-05-30
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.304 Å)
Cite:Crystal structure of WA352 provides insight into cytoplasmic male sterility in rice
Biochem. Biophys. Res. Commun., 501, 2018
5JY3
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BU of 5jy3 by Molmil
CRYSTAL STRUCTURE OF LXRbeta (NUCLEAR RECEPTOR SUBFAMILY 1, GROUP H, MEMBER 2) COMPLEXED WITH BMS-852927
Descriptor: 1,4-BUTANEDIOL, 2-[2-[2-[2,6-bis(chloranyl)phenyl]propan-2-yl]-1-[2-fluoranyl-4-[3-fluoranyl-4-(hydroxymethyl)-5-methylsulfonyl-phenyl] phenyl]imidazol-4-yl]propan-2-ol, Oxysterols receptor LXR-beta
Authors:Muckelbauer, J.K.
Deposit date:2016-05-13
Release date:2016-11-02
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of Highly Potent Liver X Receptor beta Agonists.
ACS Med Chem Lett, 7, 2016

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數據於2024-07-24公開中

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