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4R8Q
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BU of 4r8q by Molmil
Structure and substrate recruitment of the human spindle checkpoint kinase bub1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitotic checkpoint serine/threonine-protein kinase BUB1
Authors:Tomchick, D.R, Yu, H.
Deposit date:2014-09-02
Release date:2014-11-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structure and substrate recruitment of the human spindle checkpoint kinase Bub1.
Mol.Cell, 32, 2008
4R3A
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BU of 4r3a by Molmil
Erythrobacter litoralis EL346 blue-light activated histidine kinase
Descriptor: Blue-light-activated histidine kinase 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Tomchick, D.R, Rivera-Cancel, G, Gardner, K.H.
Deposit date:2014-08-14
Release date:2014-12-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Full-length structure of a monomeric histidine kinase reveals basis for sensory regulation.
Proc.Natl.Acad.Sci.USA, 111, 2014
9BLH
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BU of 9blh by Molmil
Crystal structure of calcium/calmodulin-dependent protein kinase type II subunit delta complexed with ribociclib
Descriptor: 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Calcium/calmodulin-dependent protein kinase type II subunit delta
Authors:Tomchick, D.R, Majumdar, A, Tagliabracci, V.
Deposit date:2024-04-30
Release date:2025-05-07
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Bacterial ubiquitin ligase engineered for small molecule and protein target identification
To Be Published
3BEN
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BU of 3ben by Molmil
Structure of N-(12-imidazolyl-dodecanoyl)-L-leucine inhibitor bound to the heme domain of Cytochrome P450-BM3
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cytochrome P450 102, MAGNESIUM ION, ...
Authors:Tomchick, D.R.
Deposit date:2007-11-19
Release date:2008-09-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel.
Biochemistry, 47, 2008
4M63
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BU of 4m63 by Molmil
Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ...
Authors:Tomchick, D.R, Zahm, J.A, Rosen, M.K.
Deposit date:2013-08-08
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.748 Å)
Cite:The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
Cell(Cambridge,Mass.), 155, 2013
4NPK
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BU of 4npk by Molmil
Extended-Synaptotagmin 2, C2A- and C2B-domains, calcium bound
Descriptor: CALCIUM ION, Extended synaptotagmin-2
Authors:Tomchick, D.R, Rizo, J, Xu, J.
Deposit date:2013-11-21
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.552 Å)
Cite:Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2.
Structure, 22, 2014
4NPJ
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BU of 4npj by Molmil
Extended-Synaptotagmin 2, C2A- and C2B-domains
Descriptor: ACETATE ION, CHLORIDE ION, Extended synaptotagmin-2, ...
Authors:Tomchick, D.R, Rizo, J, Xu, J.
Deposit date:2013-11-21
Release date:2014-01-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2.
Structure, 22, 2014
5T8V
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BU of 5t8v by Molmil
Chaetomium thermophilum cohesin loader SCC2, C-terminal fragment
Descriptor: CITRIC ACID, Putative uncharacterized protein
Authors:Tomchick, D.R, Yu, H, Kikuchi, S, Ouyang, Z, Borek, D, Otwinowski, Z.
Deposit date:2016-09-08
Release date:2016-10-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:Crystal structure of the cohesin loader Scc2 and insight into cohesinopathy.
Proc.Natl.Acad.Sci.USA, 113, 2016
4ONR
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BU of 4onr by Molmil
Crystal structure of Borrelia burgdorferi decorin-binding protein DbpA
Descriptor: DECORIN-BINDING PROTEIN DbpA, NICKEL (II) ION
Authors:Tomchick, D.R, Deka, R.K, Blevins, J.S.
Deposit date:2014-01-28
Release date:2014-07-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Identification of Lysine Residues in the Borrelia burgdorferi DbpA Adhesin Required for Murine Infection.
Infect.Immun., 82, 2014
3OBV
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BU of 3obv by Molmil
Autoinhibited Formin mDia1 Structure
Descriptor: Protein diaphanous homolog 1, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
Authors:Tomchick, D.R, Rosen, M.K, Otomo, T.
Deposit date:2010-08-09
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of the Formin mDia1 in autoinhibited conformation.
Plos One, 5, 2010
3PCR
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BU of 3pcr by Molmil
Structure of EspG-Arf6 complex
Descriptor: ADP-ribosylation factor 6, EspG, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Tomchick, D.R, Alto, N.M, Selyunin, A.S.
Deposit date:2010-10-21
Release date:2011-01-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The assembly of a GTPase-kinase signalling complex by a bacterial catalytic scaffold.
Nature, 469, 2011
3PCS
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BU of 3pcs by Molmil
Structure of EspG-PAK2 autoinhibitory Ialpha3 helix complex
Descriptor: EspG, Serine/threonine-protein kinase PAK 2
Authors:Tomchick, D.R, Alto, N.M, Selyunin, A.S.
Deposit date:2010-10-21
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:The assembly of a GTPase-kinase signalling complex by a bacterial catalytic scaffold.
Nature, 469, 2011
3L15
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BU of 3l15 by Molmil
Human Tead2 transcriptional factor
Descriptor: GLYCEROL, Transcriptional enhancer factor TEF-4
Authors:Tomchick, D.R, Luo, X, Tian, W.
Deposit date:2009-12-10
Release date:2010-04-07
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analysis of the YAP-binding domain of human TEAD2.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KY9
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BU of 3ky9 by Molmil
Autoinhibited Vav1
Descriptor: Proto-oncogene vav, ZINC ION
Authors:Tomchick, D.R, Rosen, M.K, Machius, M, Yu, B.
Deposit date:2009-12-04
Release date:2010-02-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.731 Å)
Cite:Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1
Cell(Cambridge,Mass.), 140, 2010
3BND
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BU of 3bnd by Molmil
Lipoxygenase-1 (Soybean), I553V Mutant
Descriptor: FE (III) ION, Seed lipoxygenase-1
Authors:Tomchick, D.R.
Deposit date:2007-12-14
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BNB
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BU of 3bnb by Molmil
Lipoxygenase-1 (Soybean) I553L Mutant
Descriptor: FE (III) ION, Seed lipoxygenase-1
Authors:Tomchick, D.R.
Deposit date:2007-12-14
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BNC
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BU of 3bnc by Molmil
Lipoxygenase-1 (Soybean) I553G Mutant
Descriptor: ACETIC ACID, FE (III) ION, Seed lipoxygenase-1
Authors:Tomchick, D.R.
Deposit date:2007-12-14
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3N5A
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BU of 3n5a by Molmil
Synaptotagmin-7, C2B-domain, calcium bound
Descriptor: CALCIUM ION, Synaptotagmin-7
Authors:Tomchick, D.R, Rizo, J, Craig, T.K.
Deposit date:2010-05-24
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.441 Å)
Cite:Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7.
Plos One, 5, 2010
3BNE
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BU of 3bne by Molmil
Lipoxygenase-1 (Soybean) I553A Mutant
Descriptor: FE (III) ION, Seed lipoxygenase-1
Authors:Tomchick, D.R.
Deposit date:2007-12-14
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
4IFZ
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BU of 4ifz by Molmil
Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, Mn(II)-AMP product bound form
Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
Deposit date:2012-12-15
Release date:2013-02-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9012 Å)
Cite:The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis.
J.Biol.Chem., 288, 2013
4IFU
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BU of 4ifu by Molmil
Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, apo form
Descriptor: FAD:protein FMN transferase, MAGNESIUM ION
Authors:Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
Deposit date:2012-12-15
Release date:2013-02-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8334 Å)
Cite:The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis.
J.Biol.Chem., 288, 2013
4IFX
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BU of 4ifx by Molmil
Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, FAD substrate bound form
Descriptor: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ...
Authors:Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
Deposit date:2012-12-15
Release date:2013-02-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.452 Å)
Cite:The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis.
J.Biol.Chem., 288, 2013
4IFW
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BU of 4ifw by Molmil
Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, ADP inhibited form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Thiamine biosynthesis lipoprotein ApbE
Authors:Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
Deposit date:2012-12-15
Release date:2013-02-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3001 Å)
Cite:The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis.
J.Biol.Chem., 288, 2013
4IG1
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BU of 4ig1 by Molmil
Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, Mg(II)-AMP product bound form
Descriptor: ACETATE ION, ADENOSINE MONOPHOSPHATE, FAD:protein FMN transferase, ...
Authors:Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
Deposit date:2012-12-15
Release date:2013-02-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4318 Å)
Cite:The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis.
J.Biol.Chem., 288, 2013
4K6J
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BU of 4k6j by Molmil
Human cohesin inhibitor WapL
Descriptor: ACETATE ION, SULFATE ION, Wings apart-like protein homolog
Authors:Tomchick, D.R, Yu, H, Ouyang, Z.
Deposit date:2013-04-16
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6205 Å)
Cite:Structure of the human cohesin inhibitor Wapl.
Proc.Natl.Acad.Sci.USA, 110, 2013

238582

數據於2025-07-09公開中

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