Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6A6K
DownloadVisualize
BU of 6a6k by Molmil
Crystal structure of Estrogen-related Receptor-3 (ERR-gamma) ligand binding domain with DN201000
Descriptor: 3-[(~{E})-5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol, Estrogen-related receptor gamma
Authors:Yoon, H, Kim, J, Chin, J, Cho, S.J, Song, J.
Deposit date:2018-06-28
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Discovery of Potent, Selective, and Orally Bioavailable Estrogen-Related Receptor-gamma Inverse Agonists To Restore the Sodium Iodide Symporter Function in Anaplastic Thyroid Cancer.
J. Med. Chem., 62, 2019
5YSO
DownloadVisualize
BU of 5yso by Molmil
Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domain with DN200434
Descriptor: 4-[5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol, Estrogen-related receptor gamma
Authors:Cho, S.J, Chin, J.W, Yoon, H.S, Jeon, Y.H, Bae, J.H, Song, J.Y.
Deposit date:2017-11-14
Release date:2018-12-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERR gamma ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer.
Clin.Cancer Res., 25, 2019
6KNR
DownloadVisualize
BU of 6knr by Molmil
Crystal structure of Estrogen-related receptor gamma ligand-binding domain with DN200699
Descriptor: (E)-4-(1-(4-(1-cyclopropylpiperidin-4-yl)phenyl)-5-hydroxy-2-phenylpent-1-en-1-yl)phenol, Estrogen-related receptor gamma
Authors:Yoon, H, Kim, J, Chin, J, Song, J, Cho, S.J.
Deposit date:2019-08-07
Release date:2020-08-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer.
Eur.J.Med.Chem., 205, 2020
7BU9
DownloadVisualize
BU of 7bu9 by Molmil
Crystal Structure of Spindlin1-H3(K4me3-K9me2) complex
Descriptor: H3(K4me3-K9me2) peptide, Spindlin-1
Authors:Zhao, F, Li, H.
Deposit date:2020-04-05
Release date:2020-10-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.502 Å)
Cite:Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1.
J.Biol.Chem., 295, 2020
7BQZ
DownloadVisualize
BU of 7bqz by Molmil
Crystal Structure of Spindlin1 bound to H3(K4me3-K9me3) peptide
Descriptor: H3(K4me3-K9me3) peptide, Spindlin-1
Authors:Zhao, F, Li, H.
Deposit date:2020-03-26
Release date:2020-10-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1.
J.Biol.Chem., 295, 2020
6JL9
DownloadVisualize
BU of 6jl9 by Molmil
Crystal structure of a frog ependymin related protein
Descriptor: CALCIUM ION, Ependymin-related 1
Authors:Park, S.Y.
Deposit date:2019-03-04
Release date:2019-07-10
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of three ependymin-related proteins suggest their function as a hydrophobic molecule binder.
Iucrj, 6, 2019
6JLD
DownloadVisualize
BU of 6jld by Molmil
Crystal structure of a human ependymin related protein
Descriptor: Mammalian ependymin-related protein 1
Authors:Park, S.Y.
Deposit date:2019-03-05
Release date:2019-07-10
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of three ependymin-related proteins suggest their function as a hydrophobic molecule binder.
Iucrj, 6, 2019
6JLA
DownloadVisualize
BU of 6jla by Molmil
Crystal structure of a mouse ependymin related protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Mammalian ependymin-related protein 1
Authors:Park, S.
Deposit date:2019-03-04
Release date:2020-03-04
Last modified:2020-09-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of three ependymin-related proteins suggest their function as a hydrophobic molecule binder.
Iucrj, 6, 2019
4ZZH
DownloadVisualize
BU of 4zzh by Molmil
SIRT1/Activator Complex
Descriptor: (4S)-N-[3-(1,3-oxazol-5-yl)phenyl]-7-[3-(trifluoromethyl)phenyl]-3,4-dihydro-1,4-methanopyrido[2,3-b][1,4]diazepine-5(2H)-carboxamide, NAD-dependent protein deacetylase sirtuin-1, ZINC ION
Authors:Dai, H.
Deposit date:2015-05-22
Release date:2015-07-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.1001 Å)
Cite:Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.
Nat Commun, 6, 2015
4ZZJ
DownloadVisualize
BU of 4zzj by Molmil
SIRT1/Activator/Substrate Complex
Descriptor: (3S)-1,3-dimethyl-N-[3-(1,3-oxazol-5-yl)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide, Ac-p53, CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Dai, H.
Deposit date:2015-05-22
Release date:2015-07-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7403 Å)
Cite:Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.
Nat Commun, 6, 2015
6O7G
DownloadVisualize
BU of 6o7g by Molmil
Solution structure of MLL4 PHD6 domain in complex with histone H4K16ac peptide
Descriptor: Histone H4, Histone-lysine N-methyltransferase 2D, ZINC ION
Authors:Zhang, Y, Kutateladze, T.G.
Deposit date:2019-03-07
Release date:2019-05-22
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
Nat Commun, 10, 2019
4ZZI
DownloadVisualize
BU of 4zzi by Molmil
SIRT1/Activator/Inhibitor Complex
Descriptor: (3S)-1,3-dimethyl-N-[3-(1,3-oxazol-5-yl)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide, 4-(4-{2-[(methylsulfonyl)amino]ethyl}piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide, NAD-dependent protein deacetylase sirtuin-1, ...
Authors:Dai, H.
Deposit date:2015-05-22
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7346 Å)
Cite:Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.
Nat Commun, 6, 2015
3DF9
DownloadVisualize
BU of 3df9 by Molmil
Crystal structure of E. coli MTA/SAH nucleosidase in complex with BnT-DADMeImmA
Descriptor: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(benzylsulfanyl)methyl]pyrrolidin-3-ol, MTA/SAH nucleosidase
Authors:Siu, K.K.W, Howell, P.L.
Deposit date:2008-06-11
Release date:2009-03-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Acta Crystallogr.,Sect.F, 64, 2008
4WKC
DownloadVisualize
BU of 4wkc by Molmil
Crystal structure of Escherichia coli 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with butylthio-DADMe-Immucillin-A
Descriptor: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, TETRAETHYLENE GLYCOL
Authors:Cameron, S.A, Thomas, K, Almo, S.C, Schramm, V.L.
Deposit date:2014-10-02
Release date:2015-08-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Active site and remote contributions to catalysis in methylthioadenosine nucleosidases.
Biochemistry, 54, 2015
2QSU
DownloadVisualize
BU of 2qsu by Molmil
Structure of Arabidopsis thaliana 5'-Methylthioadenosine nucleosidase in apo form
Descriptor: 5'-methylthioadenosine nucleosidase
Authors:Siu, K.K.W, Howell, P.L.
Deposit date:2007-07-31
Release date:2008-04-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular determinants of substrate specificity in plant 5'-methylthioadenosine nucleosidases.
J.Mol.Biol., 378, 2008
4YML
DownloadVisualize
BU of 4yml by Molmil
Crystal structure of Escherichia coli 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with (3S,4R)-methylthio-DADMe-Immucillin-A
Descriptor: (3S,4R)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(methylsulfanyl)methyl]pyrrolidin-3-ol, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, PHOSPHATE ION
Authors:Cameron, S.A, Thomas, K, Almo, S.C, Schramm, V.L.
Deposit date:2015-03-06
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Tight binding enantiomers of pre-clinical drug candidates.
Bioorg.Med.Chem., 23, 2015
3LGS
DownloadVisualize
BU of 3lgs by Molmil
A. thaliana MTA nucleosidase in complex with S-adenosylhomocysteine
Descriptor: 1,2-ETHANEDIOL, 5'-methylthioadenosine nucleosidases, ADENINE, ...
Authors:Siu, K.K.W, Howell, P.L.
Deposit date:2010-01-21
Release date:2010-06-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of substrate specificity in 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases.
J.Struct.Biol., 173, 2011
<123

 

221051

數據於2024-06-12公開中

PDB statisticsPDBj update infoContact PDBjnumon