3V9W
 
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4P5U
 | | Crystal structure of TatD | | Descriptor: | Tat-linked quality control protein TatD | | Authors: | Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S. | | Deposit date: | 2014-03-20 | | Release date: | 2014-08-27 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res., 42, 2014
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4PE8
 | | Crystal structure of TatD in complex with trinucleotide DNA | | Descriptor: | DNA (5'-D(*GP*CP*T)-3'), Tat-linked quality control protein TatD | | Authors: | Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S. | | Deposit date: | 2014-04-23 | | Release date: | 2014-08-27 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.894 Å) | | Cite: | Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res., 42, 2014
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5GKP
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5DK5
 | | Crystal structure of CRN-4-MES complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cell death-related nuclease 4, ISOPROPYL ALCOHOL, ... | | Authors: | Hsiao, Y.-Y, Yuan, H.S. | | Deposit date: | 2015-09-03 | | Release date: | 2016-08-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES)
J.Med.Chem., 59, 2016
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7CEI
 | | THE ENDONUCLEASE DOMAIN OF COLICIN E7 IN COMPLEX WITH ITS INHIBITOR IM7 PROTEIN | | Descriptor: | PROTEIN (COLICIN E7 IMMUNITY PROTEIN), ZINC ION | | Authors: | Ko, T.P, Liao, C.C, Ku, W.Y, Chak, K.F, Yuan, H.S. | | Deposit date: | 1998-09-17 | | Release date: | 1999-09-17 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The crystal structure of the DNase domain of colicin E7 in complex with its inhibitor Im7 protein.
Structure Fold.Des., 7, 1999
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3NH1
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3NH0
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3NH2
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3NGZ
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3NGY
 | | Crystal structure of RNase T (E92G mutant) | | Descriptor: | COBALT (II) ION, Ribonuclease T, his tag sequence | | Authors: | Hsiao, Y.-Y, Yuan, H.S. | | Deposit date: | 2010-06-14 | | Release date: | 2011-02-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.204 Å) | | Cite: | Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
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4IUF
 | | Crystal Structure of Human TDP-43 RRM1 Domain in Complex with a Single-stranded DNA | | Descriptor: | 5'-D(*GP*TP*TP*GP*(XUA)P*GP*CP*GP*T)-3', TAR DNA-binding protein 43 | | Authors: | Kuo, P.H, Doudeva, L.G, Wang, Y.T, Yang, W.Z, Yuan, H.S. | | Deposit date: | 2013-01-21 | | Release date: | 2014-01-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.752 Å) | | Cite: | The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids.
Nucleic Acids Res., 42, 2014
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4KB1
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4KAZ
 | | Crystal structure of RNase T in complex with a Y structured DNA | | Descriptor: | DNA (5'-D(*TP*TP*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION, Ribonuclease T | | Authors: | Hsiao, Y.-Y, Yuan, H.S. | | Deposit date: | 2013-04-23 | | Release date: | 2014-03-05 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
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4KB0
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7DA6
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7X9D
 | | DNMT3B in complex with harmine | | Descriptor: | 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE, DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B | | Authors: | Cho, C.-C, Yuan, H.S. | | Deposit date: | 2022-03-15 | | Release date: | 2023-03-15 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.08 Å) | | Cite: | Mechanistic Insights into Harmine-Mediated Inhibition of Human DNA Methyltransferases and Prostate Cancer Cell Growth.
Acs Chem.Biol., 18, 2023
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7W1R
 | | Crystal structure of human Suv3 monomer | | Descriptor: | ATP-dependent RNA helicase SUPV3L1, mitochondrial | | Authors: | Jain, M, Yuan, H.S. | | Deposit date: | 2021-11-20 | | Release date: | 2022-05-11 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Dimeric assembly of human Suv3 helicase promotes its RNA unwinding function in mitochondrial RNA degradosome for RNA decay.
Protein Sci., 31, 2022
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5GKC
 | | The crystal structure of the CPS-6 H148A/F122A | | Descriptor: | Endonuclease G, mitochondrial | | Authors: | Lin, J.L, Yuan, H.S. | | Deposit date: | 2016-07-04 | | Release date: | 2016-11-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.892 Å) | | Cite: | Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
Nucleic Acids Res., 44, 2016
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5ZKI
 | | Human EXOG-H140A in complex with duplex DNA | | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*GP*GP*GP*AP*TP*AP*TP*CP*CP*CP*G)-3'), MAGNESIUM ION, ... | | Authors: | Wu, C.C, Lin, J.L.J, Yuan, H.S. | | Deposit date: | 2018-03-24 | | Release date: | 2019-04-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.321 Å) | | Cite: | A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res., 47, 2019
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5ZKJ
 | | Human EXOG-H140A in complex with RNA/DNA hybrid duplex | | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), MAGNESIUM ION, ... | | Authors: | Wu, C.C, Lin, J.L.J, Yuan, H.S. | | Deposit date: | 2018-03-24 | | Release date: | 2019-04-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.798 Å) | | Cite: | A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res., 47, 2019
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6IID
 | | Human EXOG-H140A in complex with RNA-DNA chimeric duplex | | Descriptor: | DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), DNA/RNA (5'-R(P*CP*GP*GP*GP*A)-D(P*T)-R(P*G)-D(P*T)-R(P*CP*AP*CP*G)-3'), MAGNESIUM ION, ... | | Authors: | Wu, C.C, Lin, J.L.J, Yuan, H.S. | | Deposit date: | 2018-10-04 | | Release date: | 2019-04-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.986 Å) | | Cite: | A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res., 47, 2019
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6J7Y
 | | Human mitochondrial Oligoribonuclease in complex with DNA | | Descriptor: | DNA (5'-D(P*TP*T)-3'), MAGNESIUM ION, Oligoribonuclease, ... | | Authors: | Chu, L.Y, Agrawal, S, Yuan, H.S. | | Deposit date: | 2019-01-18 | | Release date: | 2019-08-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.203 Å) | | Cite: | Structural insights into nanoRNA degradation by human Rexo2.
Rna, 25, 2019
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6J80
 | | Human mitochondrial Oligoribonuclease in complex with poly-dT DNA | | Descriptor: | CITRIC ACID, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | | Authors: | Chu, L.Y, Agrawal, S, Yuan, H.S. | | Deposit date: | 2019-01-18 | | Release date: | 2019-08-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.812 Å) | | Cite: | Structural insights into nanoRNA degradation by human Rexo2.
Rna, 25, 2019
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6J7Z
 | | Human mitochondrial Oligoribonuclease in complex with RNA | | Descriptor: | CITRIC ACID, MAGNESIUM ION, Oligoribonuclease, ... | | Authors: | Chu, L.Y, Agrawal, S, Yuan, H.S. | | Deposit date: | 2019-01-18 | | Release date: | 2019-08-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.005 Å) | | Cite: | Structural insights into nanoRNA degradation by human Rexo2.
Rna, 25, 2019
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