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3V9W
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BU of 3v9w by Molmil
Crystal structure of RNase T in complex with a preferred ssDNA (TTA) with two Mg in the active site
Descriptor: COBALT (II) ION, DNA (5'-D(*GP*CP*TP*TP*A)-3'), MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
4P5U
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BU of 4p5u by Molmil
Crystal structure of TatD
Descriptor: Tat-linked quality control protein TatD
Authors:Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S.
Deposit date:2014-03-20
Release date:2014-08-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res., 42, 2014
4PE8
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BU of 4pe8 by Molmil
Crystal structure of TatD in complex with trinucleotide DNA
Descriptor: DNA (5'-D(*GP*CP*T)-3'), Tat-linked quality control protein TatD
Authors:Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S.
Deposit date:2014-04-23
Release date:2014-08-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.894 Å)
Cite:Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res., 42, 2014
5GKP
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BU of 5gkp by Molmil
Crystal structure of the EndoG worm homologue CPS-6 H148A/F122A in complex with DNA
Descriptor: DNA (5'-D(*TP*TP*TP*TP*T)-3'), Endonuclease G, mitochondrial, ...
Authors:Lin, J.L, Yuan, H.S.
Deposit date:2016-07-05
Release date:2016-11-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
Nucleic Acids Res., 44, 2016
5DK5
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BU of 5dk5 by Molmil
Crystal structure of CRN-4-MES complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cell death-related nuclease 4, ISOPROPYL ALCOHOL, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2015-09-03
Release date:2016-08-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES)
J.Med.Chem., 59, 2016
7CEI
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BU of 7cei by Molmil
THE ENDONUCLEASE DOMAIN OF COLICIN E7 IN COMPLEX WITH ITS INHIBITOR IM7 PROTEIN
Descriptor: PROTEIN (COLICIN E7 IMMUNITY PROTEIN), ZINC ION
Authors:Ko, T.P, Liao, C.C, Ku, W.Y, Chak, K.F, Yuan, H.S.
Deposit date:1998-09-17
Release date:1999-09-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of the DNase domain of colicin E7 in complex with its inhibitor Im7 protein.
Structure Fold.Des., 7, 1999
3NH1
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BU of 3nh1 by Molmil
Crystal structure of RNase T in complex with a preferred ssDNA (TAGG) with two Mg in the active site
Descriptor: 5'-D(*TP*TP*AP*TP*AP*GP*G)-3', MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.107 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NH0
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BU of 3nh0 by Molmil
Crystal structure of RNase T in complex with a non-preferred ssDNA (AAC)
Descriptor: 5'-D(*TP*TP*AP*CP*AP*AP*C)-3', Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NH2
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BU of 3nh2 by Molmil
Crystal structure of RNase T in complex with a stem DNA with a 3' overhang
Descriptor: 5'-D(P*TP*TP*AP*CP*AP*AP*C)-3', Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NGZ
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BU of 3ngz by Molmil
Crystal structure of RNase T in complex with a non-preferred ssDNA (GC) with one Mg in the active site
Descriptor: 5'-D(P*GP*C)-3', COBALT (II) ION, MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NGY
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BU of 3ngy by Molmil
Crystal structure of RNase T (E92G mutant)
Descriptor: COBALT (II) ION, Ribonuclease T, his tag sequence
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
4IUF
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BU of 4iuf by Molmil
Crystal Structure of Human TDP-43 RRM1 Domain in Complex with a Single-stranded DNA
Descriptor: 5'-D(*GP*TP*TP*GP*(XUA)P*GP*CP*GP*T)-3', TAR DNA-binding protein 43
Authors:Kuo, P.H, Doudeva, L.G, Wang, Y.T, Yang, W.Z, Yuan, H.S.
Deposit date:2013-01-21
Release date:2014-01-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.752 Å)
Cite:The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids.
Nucleic Acids Res., 42, 2014
4KB1
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BU of 4kb1 by Molmil
Crystal structure of RNase T in complex with a bluge DNA (two nucleotide insertion CT )
Descriptor: Bulge DNA, MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2013-04-23
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
4KAZ
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BU of 4kaz by Molmil
Crystal structure of RNase T in complex with a Y structured DNA
Descriptor: DNA (5'-D(*TP*TP*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2013-04-23
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
4KB0
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BU of 4kb0 by Molmil
Crystal structure of RNase T in complex with a bluge DNA (Two nucleotide insertion CC )
Descriptor: DNA (5'-D(*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2013-04-23
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
7DA6
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BU of 7da6 by Molmil
Enterovirus 71 2A Protease mutant- C110A in complex with peptide inhibitor
Descriptor: PHE-ARG-GLY-LYS, Polyprotein, ZINC ION
Authors:Yang, W.Z, Yuan, H.S.
Deposit date:2020-10-15
Release date:2021-08-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Efficient Strategy to Design Protease Inhibitors: Application to Enterovirus 71 2A Protease.
Acs Bio Med Chem Au, 2022
7X9D
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BU of 7x9d by Molmil
DNMT3B in complex with harmine
Descriptor: 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE, DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B
Authors:Cho, C.-C, Yuan, H.S.
Deposit date:2022-03-15
Release date:2023-03-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Mechanistic Insights into Harmine-Mediated Inhibition of Human DNA Methyltransferases and Prostate Cancer Cell Growth.
Acs Chem.Biol., 18, 2023
7W1R
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BU of 7w1r by Molmil
Crystal structure of human Suv3 monomer
Descriptor: ATP-dependent RNA helicase SUPV3L1, mitochondrial
Authors:Jain, M, Yuan, H.S.
Deposit date:2021-11-20
Release date:2022-05-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Dimeric assembly of human Suv3 helicase promotes its RNA unwinding function in mitochondrial RNA degradosome for RNA decay.
Protein Sci., 31, 2022
5GKC
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BU of 5gkc by Molmil
The crystal structure of the CPS-6 H148A/F122A
Descriptor: Endonuclease G, mitochondrial
Authors:Lin, J.L, Yuan, H.S.
Deposit date:2016-07-04
Release date:2016-11-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
Nucleic Acids Res., 44, 2016
5ZKI
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BU of 5zki by Molmil
Human EXOG-H140A in complex with duplex DNA
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*GP*GP*AP*TP*AP*TP*CP*CP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Wu, C.C, Lin, J.L.J, Yuan, H.S.
Deposit date:2018-03-24
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.321 Å)
Cite:A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res., 47, 2019
5ZKJ
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BU of 5zkj by Molmil
Human EXOG-H140A in complex with RNA/DNA hybrid duplex
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Wu, C.C, Lin, J.L.J, Yuan, H.S.
Deposit date:2018-03-24
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res., 47, 2019
6IID
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BU of 6iid by Molmil
Human EXOG-H140A in complex with RNA-DNA chimeric duplex
Descriptor: DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), DNA/RNA (5'-R(P*CP*GP*GP*GP*A)-D(P*T)-R(P*G)-D(P*T)-R(P*CP*AP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Wu, C.C, Lin, J.L.J, Yuan, H.S.
Deposit date:2018-10-04
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.986 Å)
Cite:A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res., 47, 2019
6J7Y
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BU of 6j7y by Molmil
Human mitochondrial Oligoribonuclease in complex with DNA
Descriptor: DNA (5'-D(P*TP*T)-3'), MAGNESIUM ION, Oligoribonuclease, ...
Authors:Chu, L.Y, Agrawal, S, Yuan, H.S.
Deposit date:2019-01-18
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Structural insights into nanoRNA degradation by human Rexo2.
Rna, 25, 2019
6J80
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BU of 6j80 by Molmil
Human mitochondrial Oligoribonuclease in complex with poly-dT DNA
Descriptor: CITRIC ACID, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
Authors:Chu, L.Y, Agrawal, S, Yuan, H.S.
Deposit date:2019-01-18
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.812 Å)
Cite:Structural insights into nanoRNA degradation by human Rexo2.
Rna, 25, 2019
6J7Z
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BU of 6j7z by Molmil
Human mitochondrial Oligoribonuclease in complex with RNA
Descriptor: CITRIC ACID, MAGNESIUM ION, Oligoribonuclease, ...
Authors:Chu, L.Y, Agrawal, S, Yuan, H.S.
Deposit date:2019-01-18
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Structural insights into nanoRNA degradation by human Rexo2.
Rna, 25, 2019

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數據於2024-06-12公開中

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