5ZKJ

Human EXOG-H140A in complex with RNA/DNA hybrid duplex

Summary for 5ZKJ

• Entry DOI: 10.2210/pdb5zkj/pdb
• Descriptor: Nuclease EXOG, mitochondrial, RNA (5'-R(P*CP*GP*GP*GP*AP*UP*GP*UP*CP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), ... (6 entities in total)
• Functional Keywords: enzyme-substrate complex, mitochondrial exonuclease, hydrolase-rna-dna complex, hydrolase/rna/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 93498.04

Authors

Wu, C.C.,Lin, J.L.J.,Yuan, H.S. (deposition date: 2018-03-24, release date: 2019-04-03, Last modification date: 2023-11-22)

• Primary citation: Wu, C.C.,Lin, J.L.J.,Yang-Yen, H.F.,Yuan, H.S.; A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.; Nucleic Acids Res., 47:5405-5419, 2019; PubMed: 30949702; DOI: 10.1093/nar/gkz241

Experimental method

X-RAY DIFFRACTION (2.798 Å)