5ZKJ
Human EXOG-H140A in complex with RNA/DNA hybrid duplex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nuclease EXOG, mitochondrial | polymer | 348 | 39216.3 | 2 | UniProt (Q9Y2C4) Pfam (PF01223) Pfam (PF18026) | Homo sapiens (Human) | Endonuclease G-like 1,Endo G-like 1 |
| 2 | C, E (C, E) | RNA (5'-R(P*CP*GP*GP*GP*AP*UP*GP*UP*CP*AP*CP*G)-3') | polymer | 12 | 3867.4 | 2 | synthetic construct | ||
| 3 | D, F (D, F) | DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3') | polymer | 12 | 3623.4 | 2 | synthetic construct | ||
| 4 | G, I (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | H (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | J, K, L (A, B, C) | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence modifications
A, B: 42 - 368 (UniProt: Q9Y2C4)
| PDB | External Database | Details |
|---|---|---|
| Met 21 | - | expression tag |
| Gly 22 | - | expression tag |
| Ser 23 | - | expression tag |
| Ser 24 | - | expression tag |
| His 25 | - | expression tag |
| His 26 | - | expression tag |
| His 27 | - | expression tag |
| His 28 | - | expression tag |
| His 29 | - | expression tag |
| His 30 | - | expression tag |
| Ser 31 | - | expression tag |
| Ser 32 | - | expression tag |
| Gly 33 | - | expression tag |
| Leu 34 | - | expression tag |
| Val 35 | - | expression tag |
| Pro 36 | - | expression tag |
| Arg 37 | - | expression tag |
| Gly 38 | - | expression tag |
| Ser 39 | - | expression tag |
| His 40 | - | expression tag |
| Met 41 | - | expression tag |
| Ala 140 | His 140 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 93414.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 84.1 | |
| All* | Total formula weight | 93498.0 |
