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3DPN
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BU of 3dpn by Molmil
Crystal Structure of cpaf s499a mutant
Descriptor: Protein CT_858
Authors:Chai, J, Huang, Z.
Deposit date:2008-07-09
Release date:2009-01-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for activation and inhibition of the secreted chlamydia protease CPAF
Cell Host Microbe, 4, 2008
4Y5H
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BU of 4y5h by Molmil
Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) inhibitors
Descriptor: 1-(trans-4-{[7-oxo-8-(propan-2-yl)-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}cyclohexyl)-3-propan-2-ylurea, Mitogen-activated protein kinase 10
Authors:Park, H.
Deposit date:2015-02-11
Release date:2015-05-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.055 Å)
Cite:Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) Inhibitors.
Acs Med.Chem.Lett., 6, 2015
3DJ9
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BU of 3dj9 by Molmil
Crystal Structure of an isolated, unglycosylated antibody CH2 domain
Descriptor: Ig gamma-1 chain C region
Authors:Prabakaran, P, Vu, B.K, Gan, J, Dimitrov, D.S, Ji, X.
Deposit date:2008-06-22
Release date:2008-09-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of an isolated unglycosylated antibody C(H)2 domain.
Acta Crystallogr.,Sect.D, 64, 2008
4Y46
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BU of 4y46 by Molmil
Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) inhibitors
Descriptor: 1-{trans-4-[(8-cyclopentyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]cyclohexyl}-3-propan-2-ylurea, Mitogen-activated protein kinase 10
Authors:Park, H.
Deposit date:2015-02-10
Release date:2015-05-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) Inhibitors.
Acs Med.Chem.Lett., 6, 2015
3DJA
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BU of 3dja by Molmil
Crystal Structure of cpaf solved with MAD
Descriptor: Protein CT_858
Authors:Chai, J, Huang, Z.
Deposit date:2008-06-22
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for activation and inhibition of the secreted chlamydia protease CPAF
Cell Host Microbe, 4, 2008
6JBQ
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BU of 6jbq by Molmil
CryoEM structure of Escherichia coli sigmaE transcription initiation complex containing 5nt of RNA
Descriptor: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Fang, C.L, Zhang, Y.
Deposit date:2019-01-26
Release date:2019-05-29
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6JCX
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BU of 6jcx by Molmil
Mycobacterium tuberculosis transcription initiation complex with ECF sigma factor sigma H and 6nt RNA
Descriptor: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Li, L, Zhang, Y.
Deposit date:2019-01-30
Release date:2019-05-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.903 Å)
Cite:Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6JCY
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BU of 6jcy by Molmil
Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ECF sigma factor sigH/E
Descriptor: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Li, L, Zhang, Y.
Deposit date:2019-01-30
Release date:2019-05-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6J9E
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BU of 6j9e by Molmil
Cryo-EM structure of Xanthomonos oryzae transcription elongation complex with NusA and the bacteriophage protein P7
Descriptor: 45L, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:You, L.L, Zhang, Y.
Deposit date:2019-01-22
Release date:2019-07-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Structural basis for transcription antitermination at bacterial intrinsic terminator.
Nat Commun, 10, 2019
6KJ6
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BU of 6kj6 by Molmil
cryo-EM structure of Escherichia coli Crl transcription activation complex
Descriptor: DNA (51-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Xu, J, Zhang, Y.
Deposit date:2019-07-21
Release date:2020-01-01
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor.
Elife, 8, 2019
6J9F
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BU of 6j9f by Molmil
Cryo-EM structure of Xanthomonos oryzae transcription elongation complex with the bacteriophage protein P7
Descriptor: 45L, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:You, L.L, Zhang, Y.
Deposit date:2019-01-22
Release date:2019-07-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural basis for transcription antitermination at bacterial intrinsic terminator.
Nat Commun, 10, 2019
3ISP
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BU of 3isp by Molmil
Crystal structure of ArgP from Mycobacterium tuberculosis
Descriptor: HTH-type transcriptional regulator Rv1985c/MT2039
Authors:Zhou, X, Lou, Z, Sheng, F, Bartlam, M, Wang, H, Rao, Z.
Deposit date:2009-08-27
Release date:2010-02-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of ArgP from Mycobacterium tuberculosis Confirms Two Distinct Conformations of Full-length LysR Transcriptional Regulators and Reveals Its Function in DNA Binding and Transcriptional Regulation.
J.Mol.Biol., 2009
5CD5
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BU of 5cd5 by Molmil
Crystal structure of an immature VRC01-class antibody DRVIA7 from a Chinese donor bound to clade A/E HIV-1 gp120 core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 93TH057 HIV-1 gp120 core, ...
Authors:Kong, L, Wilson, I.A.
Deposit date:2015-07-03
Release date:2016-04-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.396 Å)
Cite:Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Immunity, 44, 2016
5J7Z
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BU of 5j7z by Molmil
Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM1
Descriptor: N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)STEARAMIDE, Putative secreted endoglycosylceramidase, SODIUM ION, ...
Authors:Chen, L.
Deposit date:2016-04-07
Release date:2016-04-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Insights into the Broad Substrate Specificity of a Novel Endoglycoceramidase I Belonging to a New Subfamily of GH5 Glycosidases.
J. Biol. Chem., 292, 2017
5J14
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BU of 5j14 by Molmil
Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM3
Descriptor: N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)STEARAMIDE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Putative secreted endoglycosylceramidase, ...
Authors:Chen, L.
Deposit date:2016-03-28
Release date:2016-04-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.915 Å)
Cite:Structural Insights into the Broad Substrate Specificity of a Novel Endoglycoceramidase I Belonging to a New Subfamily of GH5 Glycosidases
J. Biol. Chem., 292, 2017
6BPH
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BU of 6bph by Molmil
Crystal structure of the chromodomain of RBBP1
Descriptor: AT-rich interactive domain-containing protein 4A, UNKNOWN ATOM OR ION
Authors:Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2017-11-23
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of chromo barrel domain of RBBP1.
Biochem. Biophys. Res. Commun., 496, 2018
6JYZ
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BU of 6jyz by Molmil
Crystal structure of endogalactoceramidase
Descriptor: 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ISOPROPYL ALCOHOL, ...
Authors:Liuqing, C, Yan, F.
Deposit date:2019-04-29
Release date:2019-10-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of an endogalactosylceramidase from Rhodococcus hoagii 103S reveals the molecular basis of its substrate specificity.
J.Struct.Biol., 208, 2019
5CD3
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BU of 5cd3 by Molmil
Structure of immature VRC01-class antibody DRVIA7
Descriptor: DRVIA7 Heavy Chain, DRVIA7 Light Chain
Authors:Kong, L, Wilson, I.A.
Deposit date:2015-07-02
Release date:2016-04-06
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Immunity, 44, 2016
5YJ6
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BU of 5yj6 by Molmil
The exoglucanase CelS from Clostridium thermocellum
Descriptor: 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diol, Dockerin type I repeat-containing protein
Authors:Liu, Y.J, Liu, S.Y, Dong, S, Li, R.M, Feng, Y.G, Cui, Q.
Deposit date:2017-10-09
Release date:2018-01-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Determination of the native features of the exoglucanase Cel48S from Clostridium thermocellum
Biotechnol Biofuels, 11, 2018
3NA9
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BU of 3na9 by Molmil
Crystal structure of Fab15
Descriptor: ACETATE ION, Fab15 heavy chain, Fab15 light chain, ...
Authors:Luo, J.
Deposit date:2010-06-01
Release date:2010-08-18
Last modified:2021-03-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Co-evolution of antibody stability and Vk CDR-L3 canonical structure
To be Published
3NAC
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BU of 3nac by Molmil
Crystal structure of Fab15 Mut7
Descriptor: ACETATE ION, Fab15 Mut7 heavy chain, Fab15 Mut7 light chain, ...
Authors:Luo, J.
Deposit date:2010-06-01
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Co-evolution of antibody stability and Vk CDR-L3 canonical structure
To be Published
3NAB
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BU of 3nab by Molmil
Crystal Structure of fab15 Mut6
Descriptor: ACETATE ION, Fab15 Mut6 heavy chain, Fab15 Mut6 light chain, ...
Authors:Luo, J.
Deposit date:2010-06-01
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Co-evolution of antibody stability and Vk CDR-L3 canonical structure
To be Published
5VGJ
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BU of 5vgj by Molmil
Crystal Structure of the Human Fab VRC38.01, an HIV-1 V1V2-Directed Neutralizing Antibody Isolated from Donor N90, bound to a scaffolded WITO V1V2 domain
Descriptor: 1FD6-V1V2-WITO, 2-acetamido-2-deoxy-beta-D-glucopyranose, VRC38.01 Fab Heavy Chain, ...
Authors:Gorman, J, Li, J, Kwong, P.D.
Deposit date:2017-04-11
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.456 Å)
Cite:Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.
Immunity, 46, 2017
4ZS3
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BU of 4zs3 by Molmil
Structural complex of 5-aminofluorescein bound to the FTO protein
Descriptor: 2-OXOGLUTARIC ACID, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, ...
Authors:Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X.
Deposit date:2015-05-13
Release date:2015-11-04
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
J.Am.Chem.Soc., 137, 2015
4ZS2
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BU of 4zs2 by Molmil
Structural complex of FTO/fluorescein
Descriptor: 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase FTO, ...
Authors:Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X.
Deposit date:2015-05-13
Release date:2015-11-04
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
J.Am.Chem.Soc., 137, 2015

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數據於2024-09-04公開中

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