2B1A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b1a by Molmil](/molmil-images/mine/2b1a) | Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG1033 peptide | Descriptor: | Fab 2219, heavy chain, light chain, ... | Authors: | Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A. | Deposit date: | 2005-09-15 | Release date: | 2006-07-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.348 Å) | Cite: | Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity. J.Virol., 80, 2006
|
|
2B4C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b4c by Molmil](/molmil-images/mine/2b4c) | Crystal structure of HIV-1 JR-FL gp120 core protein containing the third variable region (V3) complexed with CD4 and the X5 antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, T-cell surface glycoprotein CD4, ... | Authors: | Huang, C, Tang, M, Zhang, M.Y, Majeed, S, Montabana, E, Stanfield, R.L, Dimitrov, D.S, Korber, B, Sodroski, J, Wilson, I.A, Wyatt, R, Kwong, P.D. | Deposit date: | 2005-09-23 | Release date: | 2005-11-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of a V3-containing HIV-1 gp120 core. Science, 310, 2005
|
|
2AJY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ajy by Molmil](/molmil-images/mine/2ajy) | |
2AK1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ak1 by Molmil](/molmil-images/mine/2ak1) | |
2AJX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ajx by Molmil](/molmil-images/mine/2ajx) | |
2FL5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fl5 by Molmil](/molmil-images/mine/2fl5) | |
2Q7Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2q7y by Molmil](/molmil-images/mine/2q7y) | Structure of the endogenous iNKT cell ligand iGb3 bound to mCD1d | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | Authors: | Zajonc, D.M, Wilson, I.A, Teyton, L. | Deposit date: | 2007-06-07 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Valpha14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids. J.Mol.Biol., 377, 2008
|
|
2O5Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2o5y by Molmil](/molmil-images/mine/2o5y) | |
2QGE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qge by Molmil](/molmil-images/mine/2qge) | |
2QGB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qgb by Molmil](/molmil-images/mine/2qgb) | Human transthyretin (TTR) in Apo-form | Descriptor: | Transthyretin | Authors: | Connelly, S, Wilson, I.A. | Deposit date: | 2007-06-28 | Release date: | 2008-02-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors. J.Med.Chem., 51, 2008
|
|
2FK0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fk0 by Molmil](/molmil-images/mine/2fk0) | Crystal Structure of a H5N1 influenza virus hemagglutinin. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin | Authors: | Stevens, J, Wilson, I.A. | Deposit date: | 2006-01-03 | Release date: | 2006-05-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure and Receptor Specificity of the Hemagglutinin from an H5N1 Influenza Virus. Science, 312, 2006
|
|
2QGD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qgd by Molmil](/molmil-images/mine/2qgd) | |
2QSC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qsc by Molmil](/molmil-images/mine/2qsc) | Crystal structure analysis of anti-HIV-1 V3-Fab F425-B4e8 in complex with a V3-peptide | Descriptor: | CHLORIDE ION, Envelope glycoprotein gp120, Fab F425-B4e8, ... | Authors: | Bell, C.H, Schiefner, A, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2007-07-30 | Release date: | 2008-01-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization. J.Mol.Biol., 375, 2008
|
|
2QGC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qgc by Molmil](/molmil-images/mine/2qgc) | |
3ESO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eso by Molmil](/molmil-images/mine/3eso) | Human transthyretin (TTR) complexed with N-(3,5-Dibromo-4-hydroxyphenyl)-2,5-dichlorobenzamide | Descriptor: | 2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide, Transthyretin | Authors: | Connelly, S, Wilson, I.A. | Deposit date: | 2008-10-06 | Release date: | 2009-04-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Toward optimization of the second aryl substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies. J.Med.Chem., 52, 2009
|
|
7JN5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jn5 by Molmil](/molmil-images/mine/7jn5) | Crystal structure of SARS-CoV receptor binding domain in complex with human antibody CR3022 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 heavy chain, ... | Authors: | Wu, N.C, Yuan, M, Zhu, X, Wilson, I.A. | Deposit date: | 2020-08-03 | Release date: | 2020-10-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.705 Å) | Cite: | A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody. Plos Pathog., 16, 2020
|
|
7JTG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jtg by Molmil](/molmil-images/mine/7jtg) | |
7JTF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jtf by Molmil](/molmil-images/mine/7jtf) | |
3CN0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cn0 by Molmil](/molmil-images/mine/3cn0) | |
7JPH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jph by Molmil](/molmil-images/mine/7jph) | Crystal structure of EBOV glycoprotein with modified HR1c and HR2 stalk at 3.2 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ... | Authors: | Chaudhary, A, Stanfield, R.L, Wilson, I.A, Zhu, J. | Deposit date: | 2020-08-08 | Release date: | 2021-04-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.195 Å) | Cite: | Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines. Nat Commun, 12, 2021
|
|
7JPI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jpi by Molmil](/molmil-images/mine/7jpi) | Crystal structure of EBOV glycoprotein with modified HR2 stalk at 2.3A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ... | Authors: | Chaudhary, A, Stanfield, R.L, Wilson, I.A, Zhu, J. | Deposit date: | 2020-08-08 | Release date: | 2021-04-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines. Nat Commun, 12, 2021
|
|
3CFB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cfb by Molmil](/molmil-images/mine/3cfb) | |
3CFK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cfk by Molmil](/molmil-images/mine/3cfk) | Crystal structure of catalytic elimination antibody 34E4, triclinic crystal form | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN,Uncharacterized protein, ... | Authors: | Debler, E.W, Wilson, I.A. | Deposit date: | 2008-03-04 | Release date: | 2008-04-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Conformational isomerism can limit antibody catalysis. J.Biol.Chem., 283, 2008
|
|
3CN3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cn3 by Molmil](/molmil-images/mine/3cn3) | |
7KN5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7kn5 by Molmil](/molmil-images/mine/7kn5) | Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobodies VHH E and U | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | Deposit date: | 2020-11-04 | Release date: | 2021-01-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
|
|