5ZUG
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![BU of 5zug by Molmil](/molmil-images/mine/5zug) | Structure of the bacterial acetate channel SatP | Descriptor: | Succinate-acetate/proton symporter SatP, nonyl beta-D-glucopyranoside | Authors: | Sun, P.C, Li, J.L, Xiao, Q.J, Guan, Z.Y, Deng, D. | Deposit date: | 2018-05-07 | Release date: | 2018-11-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | Crystal structure of the bacterial acetate transporter SatP reveals that it forms a hexameric channel. J. Biol. Chem., 293, 2018
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4P6L
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2M4G
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![BU of 2m4g by Molmil](/molmil-images/mine/2m4g) | Solution structure of the Core Domain (11-85) of the Murine Norovirus VPg protein | Descriptor: | Murine Norovirus VPg protein | Authors: | Leen, E.N, Kwok, R, Birtley, J.R, Prater, S.N, Simpson, P.J, Matthews, S, Marchant, J, Curry, S. | Deposit date: | 2013-02-05 | Release date: | 2013-03-27 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structures of the Compact Helical Core Domains of Feline Calicivirus and Murine Norovirus VPg Proteins. J.Virol., 87, 2013
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2M4H
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![BU of 2m4h by Molmil](/molmil-images/mine/2m4h) | Solution structure of the Core Domain (10-76) of the Feline Calicivirus VPg protein | Descriptor: | Feline Calicivirus VPg protein | Authors: | Kwok, R.N, Leen, E.N, Birtley, J.R, Prater, S.N, Simpson, P.J, Curry, S, Matthews, S, Marchant, J. | Deposit date: | 2013-02-05 | Release date: | 2013-03-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structures of the Compact Helical Core Domains of Feline Calicivirus and Murine Norovirus VPg Proteins. J.Virol., 87, 2013
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4P6J
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4P6K
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3K4C
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![BU of 3k4c by Molmil](/molmil-images/mine/3k4c) | Pyranose 2-oxidase H167A/T169G mutant | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ... | Authors: | Divne, C, Tan, T.C. | Deposit date: | 2009-10-05 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A conserved active-site threonine is important for both sugar and flavin oxidations of pyranose 2-oxidase. J.Biol.Chem., 285, 2010
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3K4B
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![BU of 3k4b by Molmil](/molmil-images/mine/3k4b) | Pyranose 2-oxidase T169S mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Pyranose 2-oxidase | Authors: | Divne, C, Tan, T.C. | Deposit date: | 2009-10-05 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A conserved active-site threonine is important for both sugar and flavin oxidations of pyranose 2-oxidase. J.Biol.Chem., 285, 2010
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6BYO
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7LAF
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![BU of 7laf by Molmil](/molmil-images/mine/7laf) | 15-lipoxygenase-2 loop mutant bound to imidazole-based inhibitor | Descriptor: | 3-{[(4-methylphenyl)methyl]sulfanyl}-1-phenyl-1H-1,2,4-triazole, MANGANESE (II) ION, Polyunsaturated fatty acid lipoxygenase ALOX15B | Authors: | Newcomer, M.E, Gilbert, N.C, Neau, D.B. | Deposit date: | 2021-01-06 | Release date: | 2022-01-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2. Bioorg.Med.Chem., 46, 2021
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7JRN
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![BU of 7jrn by Molmil](/molmil-images/mine/7jrn) | Crystal structure of the wild type SARS-CoV-2 papain-like protease (PLPro) with inhibitor GRL0617 | Descriptor: | 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, SULFATE ION, ... | Authors: | Sacco, M, Ma, C, Wang, J, Chen, Y. | Deposit date: | 2020-08-12 | Release date: | 2020-08-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay. Acs Cent.Sci., 7, 2021
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6CNW
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![BU of 6cnw by Molmil](/molmil-images/mine/6cnw) | STRUCTURE OF HUMANIZED SINGLE DOMAIN ANTIBODY SD84 | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, humanized antibody SD84h | Authors: | Luo, J, Obmolova, O. | Deposit date: | 2018-03-09 | Release date: | 2018-11-14 | Method: | X-RAY DIFFRACTION (0.92 Å) | Cite: | Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science, 362, 2018
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6ES1
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6CFG
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6CF7
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6CNV
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![BU of 6cnv by Molmil](/molmil-images/mine/6cnv) | INFLUENZA B/BRISBANE HEMAGGLUTININ FAB CR9115 SD84H COMPLEX | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 Fab heavy chain, ... | Authors: | Luo, J, Obmolova, G. | Deposit date: | 2018-03-09 | Release date: | 2018-11-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science, 362, 2018
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6CK8
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2VXR
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3OHI
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![BU of 3ohi by Molmil](/molmil-images/mine/3ohi) | Structure of Giardia fructose-1,6-biphosphate aldolase in complex with 3-hydroxy-2-pyridone | Descriptor: | ({3-hydroxy-2-oxo-4-[2-(phosphonooxy)ethyl]pyridin-1(2H)-yl}methyl)phosphonic acid, Putative fructose-1,6-bisphosphate aldolase, ZINC ION | Authors: | Herzberg, O, Galkin, A. | Deposit date: | 2010-08-17 | Release date: | 2011-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Rational design, synthesis and evaluation of first generation inhibitors of the Giardia lamblia fructose-1,6-biphosphate aldolase. J.Inorg.Biochem., 105, 2010
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4O14
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![BU of 4o14 by Molmil](/molmil-images/mine/4o14) | Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors | Descriptor: | 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | Authors: | Oh, A, Coons, M, Brillantes, B, Wang, W. | Deposit date: | 2013-12-15 | Release date: | 2014-10-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.871 Å) | Cite: | Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
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4O1C
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![BU of 4o1c by Molmil](/molmil-images/mine/4o1c) | The crystal structures of a mutant NAMPT H191R | Descriptor: | 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | Authors: | Oh, A, Coons, M, Brillantes, B, Wang, W. | Deposit date: | 2013-12-15 | Release date: | 2014-10-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.092 Å) | Cite: | Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
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4O15
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![BU of 4o15 by Molmil](/molmil-images/mine/4o15) | The crystal structure of a mutant NAMPT (S165F) in complex with GNE-618 | Descriptor: | 1,2-ETHANEDIOL, N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide, Nicotinamide phosphoribosyltransferase, ... | Authors: | Oh, A, Coons, M, Brillantes, B, Wang, W. | Deposit date: | 2013-12-15 | Release date: | 2014-10-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
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4O16
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![BU of 4o16 by Molmil](/molmil-images/mine/4o16) | Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors | Descriptor: | 1,2-ETHANEDIOL, 6-({4-[(3,5-difluorophenyl)sulfonyl]benzyl}carbamoyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)imidazo[1,2-a]pyridin-1-ium, Nicotinamide phosphoribosyltransferase, ... | Authors: | Oh, A, Coons, M, Brillantes, B, Wang, W. | Deposit date: | 2013-12-15 | Release date: | 2014-10-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.783 Å) | Cite: | Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
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4O19
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![BU of 4o19 by Molmil](/molmil-images/mine/4o19) | The crystal structure of a mutant NAMPT (G217V) | Descriptor: | 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | Authors: | Oh, A, Coons, M, Brillantes, B, Wang, W. | Deposit date: | 2013-12-15 | Release date: | 2014-10-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
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4O13
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![BU of 4o13 by Molmil](/molmil-images/mine/4o13) | The crystal structure of NAMPT in complex with GNE-618 | Descriptor: | 1,2-ETHANEDIOL, N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide, Nicotinamide phosphoribosyltransferase, ... | Authors: | Oh, A, Coons, M, Brillantes, B, Wang, W. | Deposit date: | 2013-12-15 | Release date: | 2014-10-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
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