6CNW

STRUCTURE OF HUMANIZED SINGLE DOMAIN ANTIBODY SD84

Summary for 6CNW

• Entry DOI: 10.2210/pdb6cnw/pdb
• Descriptor: humanized antibody SD84h, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• Functional Keywords: single domain antibody, humanization, influenza, hemagglutinin, immune system
• Biological source: hybrid
• Total number of polymer chains: 1
• Total formula weight: 13166.55

Authors

Luo, J.,Obmolova, O. (deposition date: 2018-03-09, release date: 2018-11-14)

• Primary citation: Laursen, N.S.,Friesen, R.H.E.,Zhu, X.,Jongeneelen, M.,Blokland, S.,Vermond, J.,van Eijgen, A.,Tang, C.,van Diepen, H.,Obmolova, G.,van der Neut Kolfschoten, M.,Zuijdgeest, D.,Straetemans, R.,Hoffman, R.M.B.,Nieusma, T.,Pallesen, J.,Turner, H.L.,Bernard, S.M.,Ward, A.B.,Luo, J.,Poon, L.L.M.,Tretiakova, A.P.,Wilson, J.M.,Limberis, M.P.,Vogels, R.,Brandenburg, B.,Kolkman, J.A.,Wilson, I.A.; Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.; Science, 362:598-602, 2018; PubMed: 30385580; DOI: 10.1126/science.aaq0620

Experimental method

X-RAY DIFFRACTION (0.92 Å)