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6G32
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BU of 6g32 by Molmil
Crystal structure of human geranylgeranyl diphosphate synthase mutant D188Y
Descriptor: GLYCEROL, Geranylgeranyl pyrophosphate synthase
Authors:Lisnyansky, M, Kapelushnik, N, Ben-Bassat, A, Marom, M, Loewenstein, A, Khananshvili, D, Giladi, M, Haitin, Y.
Deposit date:2018-03-24
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.281 Å)
Cite:Reduced Activity of Geranylgeranyl Diphosphate Synthase Mutant Is Involved in Bisphosphonate-Induced Atypical Fractures.
Mol. Pharmacol., 94, 2018
8CE6
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BU of 8ce6 by Molmil
Crystal structure of human Cd11b I domain in P212121 space group
Descriptor: CHLORIDE ION, GLYCEROL, Integrin alpha-M, ...
Authors:Koekemoer, L, Williams, E, Ni, X, Gao, Q, Coker, J, MacLean, E.M, Wright, N.D, Marsden, B, Von Delft, F, Schwenzer, A, Midwood, K.
Deposit date:2023-02-01
Release date:2023-03-22
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.582 Å)
Cite:Crystal structure of human Cd11b I domain in P212121 space group
To Be Published
8CE9
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BU of 8ce9 by Molmil
Crystal structure of human Cd11b I domain in C121 space group
Descriptor: 1,2-ETHANEDIOL, Integrin alpha-M, SULFATE ION
Authors:Koekemoer, L, Williams, E, Ni, X, Gao, Q, Coker, J, MacLean, E.M, Wright, N.D, Marsden, B, Von Delft, F, Schwenzer, A, Midwood, K.
Deposit date:2023-02-01
Release date:2023-03-22
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structure of human Cd11b I domain in C121 space group
To Be Published
1IHO
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BU of 1iho by Molmil
CRYSTAL APO-STRUCTURE OF PANTOTHENATE SYNTHETASE FROM E. COLI
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PANTOATE--BETA-ALANINE LIGASE
Authors:von Delft, F, Lewendon, A, Dhanaraj, V, Blundell, T.L, Abell, C, Smith, A.
Deposit date:2001-04-19
Release date:2001-05-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of E. coli pantothenate synthetase confirms it as a member of the cytidylyltransferase superfamily.
Structure, 9, 2001
7QIG
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BU of 7qig by Molmil
Infectious mouse-adapted RML scrapie prion fibril purified from terminally-infected mouse brains
Descriptor: Major prion protein
Authors:Manka, S.W, Zhang, W, Wenborn, A, Betts, J, Joiner, S, Saibil, H.R, Collinge, J, Wadsworth, J.D.F.
Deposit date:2021-12-14
Release date:2022-07-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:2.7 angstrom cryo-EM structure of ex vivo RML prion fibrils.
Nat Commun, 13, 2022
2C4B
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BU of 2c4b by Molmil
Inhibitor cystine knot protein McoEeTI fused to the catalytically inactive barnase mutant H102A
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BARNASE MCOEETI FUSION, ...
Authors:Niemann, H.H, Schmoldt, H.U, Wentzel, A, Kolmar, H, Heinz, D.W.
Deposit date:2005-10-18
Release date:2005-11-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Barnase Fusion as a Tool to Determine the Crystal Structure of the Small Disulfide-Rich Protein Mcoeeti.
J.Mol.Biol., 356, 2006
1M9Z
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BU of 1m9z by Molmil
CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN
Descriptor: GLYCEROL, TGF-BETA RECEPTOR TYPE II
Authors:Boesen, C.C, Radaev, S, Motyka, S.A, Patamawenu, A, Sun, P.D.
Deposit date:2002-07-30
Release date:2002-09-11
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:THE 1.1A CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN
Structure, 10, 2002
1B6E
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BU of 1b6e by Molmil
HUMAN CD94
Descriptor: CD94
Authors:Boyington, J.C, Riaz, A.N, Patamawenu, A, Coligan, J.E, Brooks, A.G, Sun, P.D.
Deposit date:1999-01-14
Release date:1999-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of CD94 reveals a novel C-type lectin fold: implications for the NK cell-associated CD94/NKG2 receptors.
Immunity, 10, 1999
1CLA
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BU of 1cla by Molmil
EVIDENCE FOR TRANSITION-STATE STABILIZATION BY SERINE-148 IN THE CATALYTIC MECHANISM OF CHLORAMPHENICOL ACETYLTRANSFERASE
Descriptor: CHLORAMPHENICOL, COBALT (II) ION, TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE
Authors:Gibbs, M.R, Leslie, A.G.W.
Deposit date:1989-10-16
Release date:1990-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Evidence for transition-state stabilization by serine-148 in the catalytic mechanism of chloramphenicol acetyltransferase.
Biochemistry, 29, 1990
1CIA
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BU of 1cia by Molmil
REPLACEMENT OF CATALYTIC HISTIDINE-195 OF CHLORAMPHENICOL ACETYLTRANSFERASE: EVIDENCE FOR A GENERAL BASE ROLE FOR GLUTAMATE
Descriptor: BETA-MERCAPTOETHANOL, CHLORAMPHENICOL ACETYLTRANSFERASE, COBALT (II) ION
Authors:Leslie, A.G.W, Gibbs, M.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general base role for glutamate.
Biochemistry, 33, 1994
8KHQ
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BU of 8khq by Molmil
Bifunctional sulfoxide synthase OvoA_Th2 in complex with histidine and cysteine
Descriptor: 5-histidylcysteine sulfoxide synthase/putative 4-mercaptohistidine N1-methyltranferase, COBALT (II) ION, CYSTEINE, ...
Authors:Wang, J, Ye, K, Wang, X.Y, Yan, W.P.
Deposit date:2023-08-22
Release date:2023-12-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Biochemical and Structural Characterization of OvoA Th2 : A Mononuclear Nonheme Iron Enzyme from Hydrogenimonas thermophila for Ovothiol Biosynthesis.
Acs Catalysis, 13, 2023
6JNX
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BU of 6jnx by Molmil
Cryo-EM structure of a Q-engaged arrested complex
Descriptor: Antiterminator Q protein, DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Feng, Y, Shi, J.
Deposit date:2019-03-18
Release date:2019-06-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.08 Å)
Cite:Structural basis of Q-dependent transcription antitermination.
Nat Commun, 10, 2019
6JNY
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BU of 6jny by Molmil
Crystal structure of bacteriophage 21 Q protein
Descriptor: Antiterminator Q protein
Authors:Feng, Y, Shi, J.
Deposit date:2019-03-18
Release date:2019-06-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Structural basis of Q-dependent transcription antitermination.
Nat Commun, 10, 2019
7VWZ
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BU of 7vwz by Molmil
Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y, Shi, J.
Deposit date:2021-11-12
Release date:2022-06-08
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator.
Nucleic Acids Res., 50, 2022
7VWY
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BU of 7vwy by Molmil
Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y.
Deposit date:2021-11-12
Release date:2022-06-08
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.57 Å)
Cite:Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator.
Nucleic Acids Res., 50, 2022
7VF9
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BU of 7vf9 by Molmil
Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:He, D.W, You, L.L, Zhang, Y.
Deposit date:2021-09-10
Release date:2022-07-27
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding.
Nat Commun, 13, 2022
8GMU
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BU of 8gmu by Molmil
Structure of lambda repressor in complex with RecA filament
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Gao, B, Feng, Y.
Deposit date:2022-08-22
Release date:2022-12-21
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Structural basis for regulation of SOS response in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
8GMT
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BU of 8gmt by Molmil
Structure of UmuD in complex with RecA filament
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), DNA polymerase V subunit UmuD, MAGNESIUM ION, ...
Authors:Gao, B, Feng, Y.
Deposit date:2022-08-22
Release date:2022-12-21
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural basis for regulation of SOS response in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
8GMS
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BU of 8gms by Molmil
Structure of LexA in complex with RecA filament
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), LexA repressor, MAGNESIUM ION, ...
Authors:Gao, B, Feng, Y.
Deposit date:2022-08-22
Release date:2022-12-21
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural basis for regulation of SOS response in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
8GYB
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BU of 8gyb by Molmil
Crystal structure of Alongshan virus methyltransferase bound to S-adenosyl-L-homocysteine
Descriptor: Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Chen, H, Lin, S, Lu, G.W.
Deposit date:2022-09-22
Release date:2023-09-27
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.
Plos Pathog., 19, 2023
8GYA
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BU of 8gya by Molmil
Crystal structure of Alongshan virus methyltransferase bound to Sinefungin
Descriptor: Methyltransferase, SINEFUNGIN
Authors:Chen, H, Lin, S, Lu, G.W.
Deposit date:2022-09-21
Release date:2023-09-27
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.
Plos Pathog., 19, 2023
8GY4
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BU of 8gy4 by Molmil
Crystal structure of Alongshan virus methyltransferase
Descriptor: Methyltransferase
Authors:Chen, H, Lin, S, Lu, G.W.
Deposit date:2022-09-21
Release date:2023-09-27
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.
Plos Pathog., 19, 2023
8GY9
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BU of 8gy9 by Molmil
Crystal structure of Alongshan virus methyltransferase bound to S-adenosyl-L-methionine
Descriptor: Methyltransferase, S-ADENOSYLMETHIONINE
Authors:Chen, H, Lin, S, Lu, G.W.
Deposit date:2022-09-21
Release date:2023-09-27
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.
Plos Pathog., 19, 2023
8HML
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BU of 8hml by Molmil
Co-crystal structure of the C terminal DNA binding domain of Saccharopolyspora erythraea GlnR in complex with its conserved promoter DNA in 2.95 Angstrom resolution
Descriptor: DNA (5'-D(*AP*CP*GP*TP*AP*AP*CP*AP*TP*CP*GP*CP*GP*GP*TP*AP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*TP*AP*CP*CP*GP*CP*GP*AP*TP*GP*TP*TP*AP*CP*GP*T)-3'), DNA-binding response OmpR family regulator
Authors:Lin, W, Xu, J.C.
Deposit date:2022-12-04
Release date:2023-06-07
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural insights into the transcription activation mechanism of the global regulator GlnR from actinobacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HIH
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BU of 8hih by Molmil
Cryo-EM structure of Mycobacterium tuberculosis transcription initiation complex with transcription factor GlnR
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Shi, J, Xu, J.C.
Deposit date:2022-11-20
Release date:2023-06-07
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structural insights into the transcription activation mechanism of the global regulator GlnR from actinobacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023

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數據於2024-07-24公開中

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