8B2B
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![BU of 8b2b by Molmil](/molmil-images/mine/8b2b) | Crystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivative | Descriptor: | (4R,5R)-3-amino-4,5-dihydroxy-cyclohexene-1-carboxylic acid, 3-dehydroquinate dehydratase, SODIUM ION | Authors: | Otero, J.M, Rodriguez, A, Maneiro, M, Lence, E, Thompson, P, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | Deposit date: | 2022-09-13 | Release date: | 2023-02-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme-A molecular insight. Front Mol Biosci, 10, 2023
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4UIO
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![BU of 4uio by Molmil](/molmil-images/mine/4uio) | Structure of the Salmonella typhi Type I Dehydroquinase covalently inhibited by a 3-dehydroquinic acid derivative | Descriptor: | (1~{R},3~{R},4~{S},5~{R})-3-methyl-1,3,4,5-tetrakis(oxidanyl)cyclohexane-1-carboxylic acid, 3-DEHYDROQUINATE DEHYDRATASE, CHLORIDE ION, ... | Authors: | Otero, J.M, Llamas-Saiz, A.L, Tizon, L, Lence, E, Thompson, P, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | Deposit date: | 2015-03-30 | Release date: | 2015-07-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct. J.Am.Chem.Soc., 137, 2015
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4UE0
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![BU of 4ue0 by Molmil](/molmil-images/mine/4ue0) | |
6SFE
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![BU of 6sfe by Molmil](/molmil-images/mine/6sfe) | CRYSTAL STRUCTURE OF DHQ1 FROM SALMONELLA TYPHI COVALENTLY MODIFIED BY COMPOUND 7 | Descriptor: | (1~{S},3~{S},4~{S},5~{R})-3-(aminomethyl)-3,4,5-tris(hydroxyl)cyclohexane-1-carboxylic acid, 3-dehydroquinate dehydratase | Authors: | Sanz-Gaitero, M, Lence, E, Maneiro, M, Thompson, R, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | Deposit date: | 2019-08-01 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product. Chemistry, 26, 2020
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1OCY
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![BU of 1ocy by Molmil](/molmil-images/mine/1ocy) | Structure of the receptor-binding domain of the bacteriophage T4 short tail fibre | Descriptor: | BACTERIOPHAGE T4 SHORT TAIL FIBRE, CITRIC ACID, SULFATE ION, ... | Authors: | Thomassen, E, Gielen, G, Schuetz, M, Miller, S, van Raaij, M.J. | Deposit date: | 2003-02-11 | Release date: | 2003-07-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The Structure of the Receptor-Binding Domain of the Bacteriophage T4 Short Tail Fibre Reveals a Knitted Trimeric Metal-Binding Fold J.Mol.Biol., 331, 2003
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1PDI
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![BU of 1pdi by Molmil](/molmil-images/mine/1pdi) | Fitting of the C-terminal part of the short tail fibers into the cryo-EM reconstruction of T4 baseplate | Descriptor: | Short tail fiber protein | Authors: | Kostyuchenko, V.A, Leiman, P.G, Chipman, P.R, Kanamaru, S, van Raaij, M.J, Arisaka, F, Mesyanzhinov, V.V, Rossmann, M.G. | Deposit date: | 2003-05-19 | Release date: | 2003-09-09 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Three-dimensional structure of bacteriophage T4 baseplate Nat.Struct.Biol., 10, 2003
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1EFR
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![BU of 1efr by Molmil](/molmil-images/mine/1efr) | BOVINE MITOCHONDRIAL F1-ATPASE COMPLEXED WITH THE PEPTIDE ANTIBIOTIC EFRAPEPTIN | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BOVINE MITOCHONDRIAL F1-ATPASE SUBUNIT ALPHA, BOVINE MITOCHONDRIAL F1-ATPASE SUBUNIT BETA, ... | Authors: | Abrahams, J.P, Buchanan, S.K, Van Raaij, M.J, Fearnley, I.M, Leslie, A.G.W, Walker, J.E. | Deposit date: | 1996-05-24 | Release date: | 1997-02-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The Structure of Bovine F1-ATPase Complexed with the Peptide Antibiotic Efrapeptin. Proc.Natl.Acad.Sci.USA, 93, 1996
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5FLD
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![BU of 5fld by Molmil](/molmil-images/mine/5fld) | |
5FWZ
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![BU of 5fwz by Molmil](/molmil-images/mine/5fwz) | Fasciola hepatica calcium binding protein FhCaBP2: Structure of the dynein light chain-like domain. P41212 mercury derivative. | Descriptor: | CALCIUM BINDING PROTEIN, CHLORIDE ION, MERCURY (II) ION | Authors: | Nguyen, T.H, Thomas, C.M, Timson, D.J, van Raaij, M.J. | Deposit date: | 2016-02-22 | Release date: | 2016-04-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Fasciola hepatica calcium-binding protein FhCaBP2: structure of the dynein light chain-like domain. Parasitol. Res., 115, 2016
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5G5O
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![BU of 5g5o by Molmil](/molmil-images/mine/5g5o) | Structure of the snake adenovirus 1 hexon-interlacing LH3 protein, native | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Nguyen, T.H, Singh, A.K, Albala-Perez, B, van Raaij, M.J. | Deposit date: | 2016-05-26 | Release date: | 2017-06-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a Reptilian Adenovirus Reveals a Phage Tailspike Fold Stabilizing a Vertebrate Virus Capsid. Structure, 25, 2017
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5FJL
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![BU of 5fjl by Molmil](/molmil-images/mine/5fjl) | |
5G5N
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![BU of 5g5n by Molmil](/molmil-images/mine/5g5n) | Structure of the snake adenovirus 1 hexon-interlacing LH3 protein, methylmercury chloride derivative | Descriptor: | CHLORIDE ION, GLYCEROL, LH3 HEXON-INTERLACING CAPSID PROTEIN, ... | Authors: | Nguyen, T.H, Singh, A.K, Albala-Perez, B, van Raaij, M.J. | Deposit date: | 2016-05-26 | Release date: | 2017-06-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of a Reptilian Adenovirus Reveals a Phage Tailspike Fold Stabilizing a Vertebrate Virus Capsid. Structure, 25, 2017
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6SFH
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![BU of 6sfh by Molmil](/molmil-images/mine/6sfh) | CRYSTAL STRUCTURE OF DHQ1 FROM Staphylococcus aureus COVALENTLY MODIFIED BY LIGAND 7 | Descriptor: | (1~{S},3~{S},4~{S},5~{R})-3-(aminomethyl)-3,4,5-tris(hydroxyl)cyclohexane-1-carboxylic acid, 3-dehydroquinate dehydratase, LITHIUM ION, ... | Authors: | Sanz-Gaitero, M, Lence, E, Maneiro, M, Thompson, R, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | Deposit date: | 2019-08-01 | Release date: | 2020-04-15 | Last modified: | 2020-07-08 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product. Chemistry, 26, 2020
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6H5J
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![BU of 6h5j by Molmil](/molmil-images/mine/6h5j) | Crystal structure of DHQ1 from Salmonella typhi covalently modified by ligand 4 | Descriptor: | (3~{R})-3,4,5-tris(hydroxyl)cyclohexane-1-carboxylic acid, 3-dehydroquinate dehydratase | Authors: | Otero, J.M, Maneiro, M, Lence, E, Sanz-Gaitero, M, Thompson, P, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | Deposit date: | 2018-07-24 | Release date: | 2019-07-24 | Last modified: | 2019-10-09 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Hydroxylammonium Derivatives for Selective Active-site Lysine Modification in the Anti-virulence Bacterial Target DHQ1 Enzyme. Org Chem Front, 6, 2019
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6H5C
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![BU of 6h5c by Molmil](/molmil-images/mine/6h5c) | Crystal structure of DHQ1 from Salmonella typhi covalently modified by ligand 1 | Descriptor: | (1~{S},3~{R},4~{S},5~{R})-3-methyl-3,4,5-tris(hydroxyl)cyclohexane-1-carboxylic Acid, 3-dehydroquinate dehydratase | Authors: | Sanz-Gaitero, M, Maneiro, M, Lence, E, Otero, J.M, Thompson, P, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | Deposit date: | 2018-07-24 | Release date: | 2019-07-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Hydroxylammonium Derivatives for Selective Active-site Lysine Modification in the Anti-virulence Bacterial Target DHQ1 Enzyme. Org Chem Front, 9, 2019
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6H5D
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![BU of 6h5d by Molmil](/molmil-images/mine/6h5d) | Crystal structure of DHQ1 from Salmonella typhi covalently modified by ligand 2 | Descriptor: | (1~{S},3~{S},4~{R},5~{R})-3-methyl-1,4,5-tris(hydroxyl)cyclohexane-1-carboxylic acid, 3-dehydroquinate dehydratase | Authors: | Sanz-Gaitero, M, Maneiro, M, Lence, E, Otero, J.M, Thompson, P, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | Deposit date: | 2018-07-24 | Release date: | 2019-07-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Hydroxylammonium Derivatives for Selective Active-site Lysine Modification in the Anti-virulence Bacterial Target DHQ1 Enzyme. Org Chem Front, 9, 2019
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6H5G
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![BU of 6h5g by Molmil](/molmil-images/mine/6h5g) | Crystal structure of DHQ1 from Salmonella typhi covalently modified by ligand 3 | Descriptor: | (1~{R},3~{S},4~{R},5~{R})-3-methyl-4,5-bis(hydroxyl)cyclohexane-1-carboxylic acid, 3-dehydroquinate dehydratase | Authors: | Sanz-Gaitero, M, Maneiro, M, Lence, E, Otero, J.M, Thompson, P, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | Deposit date: | 2018-07-24 | Release date: | 2019-07-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | Hydroxylammonium Derivatives for Selective Active-site Lysine Modification in the Anti-virulence Bacterial Target DHQ1 Enzyme. Org Chem Front, 6, 2019
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6SFG
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![BU of 6sfg by Molmil](/molmil-images/mine/6sfg) | CRYSTAL STRUCTURE OF DHQ1 FROM SALMONELLA TYPHI COVALENTLY MODIFIED BY COMPOUND 9 | Descriptor: | (1~{R},3~{S},4~{R},5~{R})-3-methyl-4,5-bis(hydroxyl)cyclohexane-1-carboxylic acid, (1~{S},3~{R},4~{S},5~{R})-3-methyl-3,4,5-tris(hydroxyl)cyclohexane-1-carboxylic Acid, 3-dehydroquinate dehydratase | Authors: | Sanz-Gaitero, M, Lence, E, Maneiro, M, Thompson, R, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | Deposit date: | 2019-08-01 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product. Chemistry, 26, 2020
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2WSU
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![BU of 2wsu by Molmil](/molmil-images/mine/2wsu) | Galectin domain of porcine adenovirus type 4 NADC-1 isolate fibre | Descriptor: | GLYCEROL, NITRATE ION, PUTATIVE FIBER PROTEIN | Authors: | Guardado-Calvo, P, Munoz, E.M, Llamas-Saiz, A.L, Fox, G.C, Glasgow, J.N, van Raaij, M.J. | Deposit date: | 2009-09-10 | Release date: | 2010-08-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains. J. Virol., 84, 2010
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2WST
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![BU of 2wst by Molmil](/molmil-images/mine/2wst) | Head domain of porcine adenovirus type 4 NADC-1 isolate fibre | Descriptor: | PUTATIVE FIBER PROTEIN | Authors: | Guardado-Calvo, P, Munoz, E.M, Llamas-Saiz, A.L, Fox, G.C, Glasgow, J.N, van Raaij, M.J. | Deposit date: | 2009-09-09 | Release date: | 2010-08-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains. J. Virol., 84, 2010
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2XGF
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![BU of 2xgf by Molmil](/molmil-images/mine/2xgf) | Structure of the bacteriophage T4 long tail fibre needle-shaped receptor-binding tip | Descriptor: | CARBONATE ION, FE (II) ION, LONG TAIL FIBER PROTEIN P37 | Authors: | Bartual, S.G, Otero, J.M, Garcia-Doval, C, Llamas-Saiz, A.L, Kahn, R, Fox, G.C, van Raaij, M.J. | Deposit date: | 2010-06-03 | Release date: | 2010-11-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the bacteriophage T4 long tail fiber receptor-binding tip. Proc. Natl. Acad. Sci. U.S.A., 107, 2010
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5M9F
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![BU of 5m9f by Molmil](/molmil-images/mine/5m9f) | |
5NBH
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![BU of 5nbh by Molmil](/molmil-images/mine/5nbh) | |
5NC1
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![BU of 5nc1 by Molmil](/molmil-images/mine/5nc1) | |
5N83
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![BU of 5n83 by Molmil](/molmil-images/mine/5n83) | |