4UE0

Structure of the bovine atadenovirus type 4 fibre head protein

Summary for 4UE0

• Entry DOI: 10.2210/pdb4ue0/pdb
• Descriptor: FIBER, CARBONATE ION, THIOCYANATE ION, ... (4 entities in total)
• Functional Keywords: viral protein
• Biological source: BOVINE ADENOVIRUS 4
• Total number of polymer chains: 3
• Total formula weight: 40802.50

Authors

Nguyen, T.H.,van Raaij, M.J. (deposition date: 2014-12-14, release date: 2015-06-03, Last modification date: 2024-05-08)

Primary citation

Nguyen, T.H.,Vidovszky, M.Z.,Ballmann, M.Z.,Sanz-Gaitero, M.,Singh, A.K.,Harrach, B.,Benko, M.,van Raaij, M.J.
Crystal structure of the fibre head domain of bovine adenovirus 4, a ruminant atadenovirus.
Virol. J., 12:81-81, 2015

PubMed Abstract: In adenoviruses, primary host cell recognition is generally performed by the head domains of their homo-trimeric fibre proteins. This first interaction is reversible. A secondary, irreversible interaction subsequently takes place via other adenovirus capsid proteins and leads to a productive infection. Although many fibre head structures are known for human mastadenoviruses, not many animal adenovirus fibre head structures have been determined, especially not from those belonging to adenovirus genera other than Mastadenovirus.

PubMed: 25994880
DOI: 10.1186/s12985-015-0309-1

Experimental method

X-RAY DIFFRACTION (1.17 Å)