5FJL

Crystal structure of raptor adenovirus 1 fibre head, wild-type form

Summary for 5FJL

• Entry DOI: 10.2210/pdb5fjl/pdb
• Descriptor: FIBER PROTEIN, CHLORIDE ION (3 entities in total)
• Functional Keywords: viral protein
• Biological source: RAPTOR SIADENOVIRUS A
• Total number of polymer chains: 1
• Total formula weight: 19202.57

Authors

Nguyen, T.H.,van Raaij, M.J. (deposition date: 2015-10-09, release date: 2016-06-29, Last modification date: 2024-01-10)

Primary citation

Nguyen, T.H.,Ballmann, M.Z.,Do, H.T.,Truong, H.N.,Benko, M.,Harrach, B.,van Raaij, M.J.
Crystal Structure of Raptor Adenovirus 1 Fibre Head and Role of the Beta-Hairpin in Siadenovirus Fibre Head Domains
Virol.J., 13:106-, 2016

PubMed Abstract: Most adenoviruses recognize their host cells via an interaction of their fibre head domains with a primary receptor. The structural framework of adenovirus fibre heads is conserved between the different adenovirus genera for which crystal structures have been determined (Mastadenovirus, Aviadenovirus, Atadenovirus and Siadenovirus), but genus-specific differences have also been observed. The only known siadenovirus fibre head structure, that of turkey adenovirus 3 (TAdV-3), revealed a twisted beta-sandwich resembling the reovirus fibre head architecture more than that of other adenovirus fibre heads, plus a unique beta-hairpin embracing a neighbouring monomer. The TAdV-3 fibre head was shown to bind sialyllactose.

PubMed: 27334597
DOI: 10.1186/S12985-016-0558-7

Experimental method

X-RAY DIFFRACTION (1.47 Å)