5FLD

Crystal structure of raptor adenovirus 1 fibre head, beta-hairpin deleted form

Summary for 5FLD

• Entry DOI: 10.2210/pdb5fld/pdb
• Descriptor: FIBER PROTEIN, CHLORIDE ION (3 entities in total)
• Functional Keywords: cell adhesion
• Biological source: RAPTOR ADENOVIRUS A
• Total number of polymer chains: 1
• Total formula weight: 17822.03

Authors

Nguyen, T.H.,van Raaij, M.J. (deposition date: 2015-10-23, release date: 2016-06-29, Last modification date: 2024-05-08)

Primary citation

Nguyen, T.H.,Ballmann, M.Z.,Do, H.T.,Truong, H.N.,Benko, M.,Harrach, B.,van Raaij, M.J.
Crystal structure of raptor adenovirus 1 fibre head and role of the beta-hairpin in siadenovirus fibre head domains.
Virol. J., 13:106-106, 2016

PubMed Abstract: Most adenoviruses recognize their host cells via an interaction of their fibre head domains with a primary receptor. The structural framework of adenovirus fibre heads is conserved between the different adenovirus genera for which crystal structures have been determined (Mastadenovirus, Aviadenovirus, Atadenovirus and Siadenovirus), but genus-specific differences have also been observed. The only known siadenovirus fibre head structure, that of turkey adenovirus 3 (TAdV-3), revealed a twisted beta-sandwich resembling the reovirus fibre head architecture more than that of other adenovirus fibre heads, plus a unique beta-hairpin embracing a neighbouring monomer. The TAdV-3 fibre head was shown to bind sialyllactose.

PubMed: 27334597
DOI: 10.1186/s12985-016-0558-7

Experimental method

X-RAY DIFFRACTION (1.7 Å)