6SFE

CRYSTAL STRUCTURE OF DHQ1 FROM SALMONELLA TYPHI COVALENTLY MODIFIED BY COMPOUND 7

Summary for 6SFE

Entry DOI	10.2210/pdb6sfe/pdb
Descriptor	3-dehydroquinate dehydratase, (1~{S},3~{S},4~{S},5~{R})-3-(aminomethyl)-3,4,5-tris(hydroxyl)cyclohexane-1-carboxylic acid (3 entities in total)
Functional Keywords	lyase activity, chorismate biosynthetic process, 3-dehydroquinase, covalent inhibitor, lyase
Biological source	Salmonella typhi
Total number of polymer chains	2
Total formula weight	55772.40
Authors	Sanz-Gaitero, M.,Lence, E.,Maneiro, M.,Thompson, R.,Hawkins, A.R.,Gonzalez-Bello, C.,van Raaij, M.J. (deposition date: 2019-08-01, release date: 2020-04-15, Last modification date: 2024-01-24)
Primary citation	Lence, E.,Maneiro, M.,Sanz-Gaitero, M.,van Raaij, M.J.,Thompson, P.,Hawkins, A.R.,Gonzalez-Bello, C. Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product. Chemistry, 26:8035-8044, 2020 Cited by PubMed: 32259333 DOI: 10.1002/chem.202000759 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.08 Å)

Structure validation