1L9V
| Non Structural protein encoded by gene segment 8 of rotavirus (NSP2), an NTPase, ssRNA binding and nucleic acid helix-destabilizing protein | Descriptor: | Rotavirus-NSP2 | Authors: | Jayaram, H, Taraporewala, Z, Patton, J.T, Prasad, B.V. | Deposit date: | 2002-03-26 | Release date: | 2002-06-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Rotavirus protein involved in genome replication and packaging exhibits a HIT-like fold. Nature, 417, 2002
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5HAP
| OXA-48 beta-lactamase - S70A mutant | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, Beta-lactamase, ... | Authors: | Stojanoski, V, Adamski, C.J, Hu, L, Mehta, S.C, Sankaran, B, Prasad, B.V.V, Palzkill, T.G. | Deposit date: | 2015-12-30 | Release date: | 2016-09-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine beta-Lactamases by Relieving Steric Strain. Biochemistry, 55, 2016
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5HAR
| OXA-163 beta-lactamase - S70G mutant | Descriptor: | ACETATE ION, Beta-lactamase, CHLORIDE ION | Authors: | Stojanoski, V, Adamski, C.J, Hu, L, Mehta, S.C, Sankaran, B, Prasad, B.V.V, Palzkill, T.G. | Deposit date: | 2015-12-30 | Release date: | 2016-09-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine beta-Lactamases by Relieving Steric Strain. Biochemistry, 55, 2016
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5HAQ
| OXa-48 beta-lactamase mutant - S70G | Descriptor: | Beta-lactamase, CADMIUM ION, FORMIC ACID | Authors: | Stojanoski, V, Adamski, C.J, Hu, L, Mehta, S.C, Sankaran, B, Prasad, B.V.V, Palzkill, T.G. | Deposit date: | 2015-12-30 | Release date: | 2016-09-07 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine beta-Lactamases by Relieving Steric Strain. Biochemistry, 55, 2016
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5HAI
| P99 beta-lactamase mutant - S64G | Descriptor: | Beta-lactamase, PHOSPHATE ION | Authors: | Stojanoski, V, Adamski, C.J, Hu, L, Mehta, S.C, Sankaran, B, Prasad, B.V.V, Palzkill, T.G. | Deposit date: | 2015-12-30 | Release date: | 2016-09-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine beta-Lactamases by Relieving Steric Strain. Biochemistry, 55, 2016
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7RSW
| Crystal structure of group B human rotavirus VP8* | Descriptor: | Outer capsid protein VP4, peptide | Authors: | Hu, L, Salmen, W, Sankaran, B, Prasad, B.V. | Deposit date: | 2021-08-11 | Release date: | 2022-07-20 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Novel fold of rotavirus glycan-binding domain predicted by AlphaFold2 and determined by X-ray crystallography. Commun Biol, 5, 2022
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5VX4
| VP8* of a G2P[4] Human Rotavirus | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Outer capsid protein VP4 | Authors: | Hu, L, Venkataram Prasad, B.V. | Deposit date: | 2017-05-23 | Release date: | 2018-07-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Glycan recognition in globally dominant human rotaviruses. Nat Commun, 9, 2018
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5VX8
| VP8* of P[6] Human Rotavirus RV3 | Descriptor: | Outer capsid protein VP4, SULFATE ION | Authors: | Hu, L, Venkataram Prasad, B.V. | Deposit date: | 2017-05-23 | Release date: | 2018-07-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Glycan recognition in globally dominant human rotaviruses. Nat Commun, 9, 2018
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5VX5
| VP8* of a G2P[4] Human Rotavirus in complex with LNFP1 | Descriptor: | Outer capsid protein VP4, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Hu, L, Venkataram Prasad, B.V. | Deposit date: | 2017-05-23 | Release date: | 2018-07-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.285 Å) | Cite: | Glycan recognition in globally dominant human rotaviruses. Nat Commun, 9, 2018
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2GE7
| Structure of the C-terminal dimerization domain of infectious bronchitis virus nucleocapsid protein | Descriptor: | Nucleocapsid protein | Authors: | Jayaram, H, Fan, H, Bowman, B.R, Ooi, A, Jayaram, J, Collisson, E.W, Lescar, J, Prasad, B.V. | Deposit date: | 2006-03-18 | Release date: | 2006-06-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structures of the N- and C-terminal domains of a coronavirus nucleocapsid protein: implications for nucleocapsid formation. J.Virol., 80, 2006
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2GX9
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6PCU
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3JYI
| Structural and biochemical evidence that a TEM-1 {beta}-lactamase Asn170Gly active site mutant acts via substrate-assisted catalysis | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase TEM, PHOSPHATE ION | Authors: | Brown, N.G, Palzkill, T.G, Prasad, B.V.V, Shanker, S. | Deposit date: | 2009-09-21 | Release date: | 2009-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Structural and biochemical evidence that a TEM-1 beta-lactamase N170G active site mutant acts via substrate-assisted catalysis J.Biol.Chem., 284, 2009
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7UON
| CTX-M-14 Y105W mutant | Descriptor: | Beta-lactamase, PHOSPHATE ION | Authors: | Judge, A, Hu, L, Sankaran, B, Van Riper, J, Prasad, B.V.V, Palzkill, T. | Deposit date: | 2022-04-13 | Release date: | 2023-01-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M beta-lactamase. Commun Biol, 6, 2023
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3M8L
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4YG0
| Structural basis of glycan recognition in neonate-specific rotaviruses | Descriptor: | Outer capsid protein VP4, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Hu, L, Prasad, B.V.V. | Deposit date: | 2015-02-25 | Release date: | 2015-09-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.285 Å) | Cite: | Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus. Nat Commun, 6, 2015
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4YG3
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4YG6
| Structural basis of glycan recognition in neonate-specific rotaviruses | Descriptor: | Outer capsid protein VP8*, PHOSPHATE ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Hu, L, Prasad, B.V.V. | Deposit date: | 2015-02-25 | Release date: | 2015-09-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus. Nat Commun, 6, 2015
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4YFW
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4YE2
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4YFZ
| Structural basis of glycan recognition in neonate-specific rotaviruses | Descriptor: | Outer capsid protein VP4, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Hu, L, Prasad, B.V.V. | Deposit date: | 2015-02-25 | Release date: | 2015-09-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus. Nat Commun, 6, 2015
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4DS0
| Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen | Descriptor: | Outer capsid protein VP4, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Hu, L, Crawford, S.E, Czako, R, Cortes-Penfield, N.W, Smith, D.F, Le Pendu, J, Estes, M.K, Prasad, B.V.V. | Deposit date: | 2012-02-17 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen. Nature, 485, 2012
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4DRV
| Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen | Descriptor: | Outer capsid protein VP4, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]alpha-D-galactopyranose | Authors: | Hu, L, Crawford, S.E, Czako, R, Cortes-Penfield, N.W, Smith, D.F, Le Pendu, J, Estes, M.K, Prasad, B.V.V. | Deposit date: | 2012-02-17 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen. Nature, 485, 2012
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4DRR
| Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen | Descriptor: | Outer capsid protein VP4, SODIUM ION | Authors: | Hu, L, Crawford, S.E, Czako, R, Cortes-Penfield, N.W, Smith, D.F, Le Pendu, J, Estes, M.K, Prasad, B.V.V. | Deposit date: | 2012-02-17 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen. Nature, 485, 2012
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4F6H
| Mutagenesis of zinc ligand residue Cys221 reveals plasticity in the IMP-1 metallo-b-lactamase active site | Descriptor: | Beta-lactamase, PHOSPHATE ION, SULFATE ION, ... | Authors: | Horton, L.B, Shanker, S, Sankaran, B, Mikulski, R, Brown, N.G, Phillips, K, Lykissa, E, Prasad, B.V.V, Palzkill, T.G. | Deposit date: | 2012-05-14 | Release date: | 2013-03-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.744 Å) | Cite: | Mutagenesis of zinc ligand residue Cys221 reveals plasticity in the IMP-1 metallo-beta-lactamase active site Antimicrob.Agents Chemother., 56, 2012
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