5HAQ

OXa-48 beta-lactamase mutant - S70G

Summary for 5HAQ

Entry DOI	10.2210/pdb5haq/pdb
Related	5HAI 5HAP 5HAR
Descriptor	Beta-lactamase, CADMIUM ION, FORMIC ACID, ... (4 entities in total)
Functional Keywords	hydrolase, serine beta-lactamase
Biological source	Klebsiella pneumoniae
Total number of polymer chains	2
Total formula weight	56418.96
Authors	Stojanoski, V.,Adamski, C.J.,Hu, L.,Mehta, S.C.,Sankaran, B.,Prasad, B.V.V.,Palzkill, T.G. (deposition date: 2015-12-30, release date: 2016-09-07, Last modification date: 2019-12-11)
Primary citation	Stojanoski, V.,Adamski, C.J.,Hu, L.,Mehta, S.C.,Sankaran, B.,Zwart, P.,Prasad, B.V.,Palzkill, T. Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine beta-Lactamases by Relieving Steric Strain. Biochemistry, 55:2479-2490, 2016 Cited by PubMed: 27073009 DOI: 10.1021/acs.biochem.6b00056 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.14 Å)

Structure validation