5HAR

OXA-163 beta-lactamase - S70G mutant

Summary for 5HAR

• Entry DOI: 10.2210/pdb5har/pdb
• Related: 5HAI 5HAP 5HAQ
• Descriptor: Beta-lactamase, ACETATE ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: hydrolase, serine beta-lactamase
• Biological source: Enterobacter cloacae
• Total number of polymer chains: 1
• Total formula weight: 27564.56

Authors

Stojanoski, V.,Adamski, C.J.,Hu, L.,Mehta, S.C.,Sankaran, B.,Prasad, B.V.V.,Palzkill, T.G. (deposition date: 2015-12-30, release date: 2016-09-07, Last modification date: 2023-11-15)

• Primary citation: Stojanoski, V.,Adamski, C.J.,Hu, L.,Mehta, S.C.,Sankaran, B.,Zwart, P.,Prasad, B.V.,Palzkill, T.; Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine beta-Lactamases by Relieving Steric Strain.; Biochemistry, 55:2479-2490, 2016; PubMed: 27073009; DOI: 10.1021/acs.biochem.6b00056

Experimental method

X-RAY DIFFRACTION (1.74 Å)