5HAP
OXA-48 beta-lactamase - S70A mutant
Summary for 5HAP
Entry DOI | 10.2210/pdb5hap/pdb |
Related | 5HAI 5HAQ 5HAR |
Descriptor | Beta-lactamase, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... (10 entities in total) |
Functional Keywords | hydrolase, serine beta-lactamase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 2 |
Total formula weight | 57935.00 |
Authors | Stojanoski, V.,Adamski, C.J.,Hu, L.,Mehta, S.C.,Sankaran, B.,Prasad, B.V.V.,Palzkill, T.G. (deposition date: 2015-12-30, release date: 2016-09-07, Last modification date: 2023-11-15) |
Primary citation | Stojanoski, V.,Adamski, C.J.,Hu, L.,Mehta, S.C.,Sankaran, B.,Zwart, P.,Prasad, B.V.,Palzkill, T. Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine beta-Lactamases by Relieving Steric Strain. Biochemistry, 55:2479-2490, 2016 Cited by PubMed: 27073009DOI: 10.1021/acs.biochem.6b00056 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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