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5VSL
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BU of 5vsl by Molmil
Crystal structure of viperin with bound [4Fe-4S] cluster and S-adenosylhomocysteine (SAH)
Descriptor: IRON/SULFUR CLUSTER, Radical S-adenosyl methionine domain-containing protein 2, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Fenwick, M.K, Li, Y, Cresswell, P, Modis, Y, Ealick, S.E.
Deposit date:2017-05-11
Release date:2017-06-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.972 Å)
Cite:Structural studies of viperin, an antiviral radical SAM enzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3M45
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BU of 3m45 by Molmil
Crystal structure of Ig1 domain of mouse SynCAM 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell adhesion molecule 2
Authors:Yue, L, Modis, Y.
Deposit date:2010-03-10
Release date:2010-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:N-glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion.
J.Biol.Chem., 285, 2010
2I69
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BU of 2i69 by Molmil
Crystal structure of the West Nile virus envelope glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Polyprotein
Authors:Kanai, R, Modis, Y.
Deposit date:2006-08-28
Release date:2006-11-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Crystal structure of west nile virus envelope glycoprotein reveals viral surface epitopes.
J.Virol., 80, 2006
4DQ7
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BU of 4dq7 by Molmil
Structural Investigation of Bacteriophage Phi6 Lysin (V207F mutant)
Descriptor: Membrane protein Phi6 P5
Authors:Dessau, M.A, Modis, Y.
Deposit date:2012-02-15
Release date:2013-01-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme.
PLoS Genet, 8, 2012
4DQJ
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BU of 4dqj by Molmil
Structural Investigation of Bacteriophage Phi6 Lysin (in complex with chitotetraose)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, Membrane protein Phi6 P5
Authors:Dessau, M.A, Modis, Y.
Deposit date:2012-02-16
Release date:2013-01-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme.
PLoS Genet, 8, 2012
3NEC
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BU of 3nec by Molmil
Crystal Structure of Toxoplasma gondii Profilin
Descriptor: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Inflammatory profilin, SULFATE ION
Authors:Kucera, K, Modis, Y.
Deposit date:2010-06-08
Release date:2010-09-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based analysis of Toxoplasma gondii profilin: a parasite-specific motif is required for recognition by Toll-like receptor 11.
J.Mol.Biol., 403, 2010
8P0C
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BU of 8p0c by Molmil
Rubella virus p150 macro domain (apo)
Descriptor: Non-structural polyprotein p200
Authors:Stoll, G.A, Modis, Y.
Deposit date:2023-05-10
Release date:2024-01-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure and biochemical activity of the macrodomain from rubella virus p150.
J.Virol., 98, 2024
8P0E
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BU of 8p0e by Molmil
Rubella virus p150 macro domain in complex with ADP-ribose
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural polyprotein p200
Authors:Stoll, G.A, Modis, Y.
Deposit date:2023-05-10
Release date:2024-01-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Crystal structure and biochemical activity of the macrodomain from rubella virus p150.
J.Virol., 98, 2024
4JNT
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BU of 4jnt by Molmil
Crystal structure of the ectodomain of Bovine viral diarrhea virus 1 E2 envelope protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2
Authors:Li, Y, Wang, J, Modis, Y.
Deposit date:2013-03-15
Release date:2013-04-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.09 Å)
Cite:Crystal structure of glycoprotein E2 from bovine viral diarrhea virus.
Proc.Natl.Acad.Sci.USA, 110, 2013
7NIC
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BU of 7nic by Molmil
CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(minor class)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-02-11
Release date:2021-11-17
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
7NGA
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BU of 7nga by Molmil
CryoEM structure of the MDA5-dsRNA filament in complex with ADP with 88-degree helical twist
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*G)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-02-08
Release date:2021-11-17
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
7NIQ
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BU of 7niq by Molmil
CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(Major class)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-02-13
Release date:2021-11-17
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
7BKQ
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BU of 7bkq by Molmil
CryoEM structure of MDA5-dsRNA filament in complex with ADP with 92-degree helical twist
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Isoform 2 of Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-01-17
Release date:2021-11-17
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
7BKP
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BU of 7bkp by Molmil
CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, MAGNESIUM ION, ...
Authors:Singh, R, Herrero del Valle, A, Yu, Q, Modis, Y.
Deposit date:2021-01-16
Release date:2021-11-17
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
6T1B
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BU of 6t1b by Molmil
Crystal structure of YlmD from Geobacillus stearothermophilus in complex with inosine
Descriptor: INOSINE, YlmD, ZINC ION
Authors:Reikine, S, Modis, Y.
Deposit date:2019-10-03
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle.
Cell, 180, 2020
6T0Y
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BU of 6t0y by Molmil
Crystal structure of YlmD from Geobacillus stearothermophilus
Descriptor: Polyphenol oxidase, ZINC ION
Authors:Reikine, S, Modis, Y.
Deposit date:2019-10-03
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle.
Cell, 180, 2020
6TL1
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BU of 6tl1 by Molmil
Crystal structure of the TASOR pseudo-PARP domain
Descriptor: GLYCEROL, Protein TASOR
Authors:Douse, C.H, Timms, R.T, Freund, S.M.V, Modis, Y.
Deposit date:2019-11-29
Release date:2020-09-16
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control.
Nat Commun, 11, 2020
4KW6
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BU of 4kw6 by Molmil
Crystal structure of Peroxiredoxin-1 (C-terminal truncation mutant) from the human hookworm Ancylostoma ceylanicum bound to conoidin A
Descriptor: 2,3-bis(bromomethyl)quinoxaline 1,4-dioxide, Peroxiredoxin-1
Authors:Nguyen, J.B, Modis, Y.
Deposit date:2013-05-23
Release date:2013-07-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Peroxiredoxin-1 from the Human Hookworm Ancylostoma ceylanicum Forms a Stable Oxidized Decamer and Is Covalently Inhibited by Conoidin A.
Chem.Biol., 20, 2013
1RHZ
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BU of 1rhz by Molmil
The structure of a protein conducting channel
Descriptor: Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta
Authors:van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A.
Deposit date:2003-11-15
Release date:2004-01-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:X-ray structure of a protein-conducting channel.
Nature, 427, 2004
1RH5
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BU of 1rh5 by Molmil
The structure of a protein conducting channel
Descriptor: Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta
Authors:van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A.
Deposit date:2003-11-13
Release date:2004-01-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:X-ray structure of a protein-conducting channel
Nature, 427, 2004
6G1X
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BU of 6g1x by Molmil
CryoEM structure of the MDA5-dsRNA filament with 91-degree helical twist
Descriptor: Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-03-22
Release date:2018-11-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6G1S
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BU of 6g1s by Molmil
CryoEM structure of the MDA5-dsRNA filament with 87-degree helical twist
Descriptor: Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-03-21
Release date:2018-11-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6G19
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BU of 6g19 by Molmil
CryoEM structure of the MDA5-dsRNA filament with 74-degree helical twist
Descriptor: Interferon-induced helicase C domain-containing protein 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-03-20
Release date:2018-11-21
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6H61
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BU of 6h61 by Molmil
CryoEM structure of the MDA5-dsRNA filament with 89 degree twist and without nucleotide
Descriptor: Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-07-25
Release date:2018-11-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6GKM
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BU of 6gkm by Molmil
CryoEM structure of the MDA5-dsRNA filament in complex with ATP (10 mM)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-05-21
Release date:2018-11-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018

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數據於2024-10-30公開中

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