3NDP
 
 | | Crystal structure of human AK4(L171P) | | Descriptor: | Adenylate kinase isoenzyme 4, SULFATE ION | | Authors: | Liu, R, Wang, Y, Wei, Z, Gong, W. | | Deposit date: | 2010-06-07 | | Release date: | 2010-06-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of human adenylate kinase 4 (L171P) suggests the role of hinge region in protein domain motion
Biochem.Biophys.Res.Commun., 379, 2009
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5HI3
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5WPV
 | | Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs at 3.59 Angstrom resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION | | Authors: | Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y. | | Deposit date: | 2017-08-07 | | Release date: | 2017-10-18 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.
Nature, 550, 2017
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3PAW
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3N8S
 | | Crystal Structure of BlaC-E166A covalently bound with Cefamandole | | Descriptor: | (2R)-2-[(1R)-1-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-2-oxoethyl]-5-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, PHOSPHATE ION | | Authors: | Tremblay, L.W, Blanchard, J.S. | | Deposit date: | 2010-05-28 | | Release date: | 2010-11-24 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of the Michaelis Complex (1.2 A) and the Covalent Acyl Intermediate (2.0 A) of Cefamandole Bound in the Active Sites of the Mycobacterium tuberculosis beta-Lactamase K73A and E166A Mutants.
Biochemistry, 49, 2010
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5WPQ
 | | Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed I conformation at 3.64 Angstrom resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION | | Authors: | Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y. | | Deposit date: | 2017-08-07 | | Release date: | 2017-10-18 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (3.64 Å) | | Cite: | Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.
Nature, 550, 2017
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4QB8
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5CH8
 | | Crystal structure of MDLA N225Q mutant form Penicillium cyclopium | | Descriptor: | CHLORIDE ION, GLYCEROL, Mono- and diacylglycerol lipase, ... | | Authors: | Xu, J, Xu, H, Hou, S, Liu, J. | | Deposit date: | 2015-07-10 | | Release date: | 2016-04-20 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Lipase-Driven Epoxidation Is A Two-Stage Synergistic Process
ChemistrySelect, 4, 2016
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2IPA
 | | solution structure of Trx-ArsC complex | | Descriptor: | Protein arsC, Thioredoxin | | Authors: | Jin, C, Hu, Y, Li, Y, Zhang, X. | | Deposit date: | 2006-10-12 | | Release date: | 2007-02-13 | | Last modified: | 2021-11-10 | | Method: | SOLUTION NMR | | Cite: | Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis.
J.Biol.Chem., 282, 2007
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2I8L
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1RYQ
 | | Putative DNA-directed RNA polymerase, subunit e'' from Pyrococcus Furiosus Pfu-263306-001 | | Descriptor: | DNA-directed RNA polymerase, subunit e'', ZINC ION | | Authors: | Liu, Z.-J, Chen, L, Tempel, W, Shah, A, Arendall III, W.B, Rose, J.P, Brereton, P.S, Izumi, M, Jenney Jr, F.E, Lee, H.S, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Richardson, D.C, Richardson, J.S, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | Deposit date: | 2003-12-22 | | Release date: | 2004-08-10 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | Parameter-space screening: a powerful tool for high-throughput crystal structure determination.
Acta Crystallogr.,Sect.D, 61, 2005
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2I6K
 | | Crystal structure of human type I IPP isomerase complexed with a substrate analog | | Descriptor: | ACETIC ACID, AMINOETHANOLPYROPHOSPHATE, Isopentenyl-diphosphate delta-isomerase 1, ... | | Authors: | Zhang, C, Wei, Z, Gong, W. | | Deposit date: | 2006-08-29 | | Release date: | 2007-06-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of human IPP isomerase: new insights into the catalytic mechanism
J.Mol.Biol., 366, 2007
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7W77
 | | cryo-EM structure of human NaV1.3/beta1/beta2-bulleyaconitineA | | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Jiang, D, Li, X. | | Deposit date: | 2021-12-03 | | Release date: | 2022-04-06 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis for modulation of human Na V 1.3 by clinical drug and selective antagonist.
Nat Commun, 13, 2022
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7W7F
 | | Cryo-EM structure of human NaV1.3/beta1/beta2-ICA121431 | | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2,2-diphenyl-~{N}-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]ethanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Jiang, D, Li, X. | | Deposit date: | 2021-12-04 | | Release date: | 2022-04-06 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structural basis for modulation of human Na V 1.3 by clinical drug and selective antagonist.
Nat Commun, 13, 2022
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3R0L
 | | Crystal structure of crotoxin | | Descriptor: | ACETATE ION, CHLORIDE ION, Crotoxin chain A, ... | | Authors: | Saul, F.A, Faure, G. | | Deposit date: | 2011-03-08 | | Release date: | 2011-10-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Crystal Structure of Crotoxin Reveals Key Residues Involved in the Stability and Toxicity of This Potent Heterodimeric Beta-Neurotoxin
J.Mol.Biol., 412, 2011
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3SAJ
 | | Crystal Structure of glutamate receptor GluA1 Amino Terminal Domain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 1, ... | | Authors: | Jin, R, Zong, Y, Yao, G, Gu, S. | | Deposit date: | 2011-06-02 | | Release date: | 2011-06-22 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the glutamate receptor GluA1 N-terminal domain.
Biochem.J., 438, 2011
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7EBX
 | | Crystal structure of juvenile hormone acid methyltransferase JHAMT in complex with S-adenosyl-L-homocysteine. | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, juvenile hormone acid methyltransferase | | Authors: | Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. | | Deposit date: | 2021-03-11 | | Release date: | 2021-09-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase.
J.Biol.Chem., 297, 2021
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7EBS
 | | Crystal structure of juvenile hormone acid methyltransferase JHAMT from silkworm | | Descriptor: | Juvenile hormone acid methyltransferase | | Authors: | Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. | | Deposit date: | 2021-03-11 | | Release date: | 2021-09-29 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase.
J.Biol.Chem., 297, 2021
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7EC0
 | | Crystal structure of juvenile hormone acid methyltransferase JHAMT in complex with S-Adenosyl homocysteine and methyl farnesoate | | Descriptor: | Juvenile hormone acid methyltransferase, Methyl farnesoate, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. | | Deposit date: | 2021-03-11 | | Release date: | 2021-09-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.494 Å) | | Cite: | Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase.
J.Biol.Chem., 297, 2021
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8HFR
 | | NPC-trapped pre-60S particle | | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Li, Z.Q, Chen, S.J, Sui, S.F. | | Deposit date: | 2022-11-12 | | Release date: | 2023-04-12 | | Last modified: | 2023-06-28 | | Method: | ELECTRON MICROSCOPY (2.64 Å) | | Cite: | Nuclear export of pre-60S particles through the nuclear pore complex.
Nature, 618, 2023
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8HBN
 | | Structure of the Mex67-Mtr2-1 heterodimer | | Descriptor: | mRNA export factor MEX67, mRNA transport regulator MTR2 | | Authors: | Li, Z.Q, Chen, S.J, Sui, S.F. | | Deposit date: | 2022-10-29 | | Release date: | 2023-04-12 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.81 Å) | | Cite: | Nuclear export of pre-60S particles through the nuclear pore complex.
Nature, 618, 2023
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8HFJ
 | | Crystal Structure of CbAR mutant (H162F) in complex with NADP+ and a bulky 1,3-cyclodiketone | | Descriptor: | 2-methyl-2-[(4-methylphenyl)methyl]cyclopentane-1,3-dione, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Versicolorin reductase | | Authors: | Hou, X.D, Yin, D.J, Rao, Y.J. | | Deposit date: | 2022-11-10 | | Release date: | 2023-06-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural analysis of an anthrol reductase inspires enantioselective synthesis of enantiopure hydroxycycloketones and beta-halohydrins.
Nat Commun, 14, 2023
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8HFK
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8H4U
 | | Cryo-EM structure of a riboendonuclease | | Descriptor: | CRISPR-associated endonuclease Cas9 | | Authors: | Li, Z, Wang, F. | | Deposit date: | 2022-10-11 | | Release date: | 2023-08-30 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural Basis for the Ribonuclease Activity of a Thermostable CRISPR-Cas13a from Thermoclostridium caenicola.
J.Mol.Biol., 435, 2023
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8H6U
 | | Class I sesquiterpene synthase BCBOT2 (complex) | | Descriptor: | MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, PYROPHOSPHATE 2-, ... | | Authors: | Lou, T.T, Ma, M. | | Deposit date: | 2022-10-18 | | Release date: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis.
J.Am.Chem.Soc., 2023
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