3A99
 
 | | Structure of PIM-1 kinase crystallized in the presence of P27KIP1 Carboxy-terminal peptide | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Proto-oncogene serine/threonine-protein kinase pim-1 | | Authors: | Morishita, D, Takami, M, Yoshikawa, S, Katayama, R, Sato, S, Kukimoto-Niino, M, Umehara, T, Shirouzu, M, Sekimizu, K, Yokoyama, S, Fujita, N. | | Deposit date: | 2009-10-22 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Cell-permeable carboxyl-terminal p27(Kip1) peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase
J.Biol.Chem., 286, 2011
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2ZET
 | | Crystal structure of the small GTPase Rab27B complexed with the Slp homology domain of Slac2-a/melanophilin | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Melanophilin, ... | | Authors: | Kukimoto-Niino, M, Sakamoto, A, Kanno, E, Hanawa-Suetsugu, K, Terada, T, Shirouzu, M, Fukuda, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-12-17 | | Release date: | 2008-09-30 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases.
Structure, 16, 2008
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3WPS
 | | crystal structure of the GAP domain of MgcRacGAP(S387D) | | Descriptor: | Rac GTPase-activating protein 1, SULFATE ION | | Authors: | Murayama, K, Kato-murayama, M, Shirouzu, M, Kitamura, T, Yokoyama, S. | | Deposit date: | 2014-01-15 | | Release date: | 2015-01-21 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | crystal structure of the GAP domain of MgcRacGAP
To be Published
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2ZKW
 | | Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group P21 | | Descriptor: | COPPER (I) ION, Superoxide dismutase [Cu-Zn], ZINC ION | | Authors: | Yoshikawa, S, Kukimoto-Niino, M, Ito, K, Chen, L, Fu, Z.Q, Chrzas, J, Wang, B.C, Shirouzu, M, Urushitani, M, Takahashi, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2008-03-31 | | Release date: | 2009-03-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group P21
To be Published
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3AQV
 | | Human AMP-activated protein kinase alpha 2 subunit kinase domain (T172D) complexed with compound C | | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-2, 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine | | Authors: | Handa, N, Takagi, T, Saijo, S, Kishishita, S, Toyama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2010-11-19 | | Release date: | 2011-04-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structural basis for compound C inhibition of the human AMP-activated protein kinase alpha 2 subunit kinase domain
Acta Crystallogr.,Sect.D, 67, 2011
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3WPQ
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6ACR
 | | Crystal structure of human ALK2 kinase domain with R206H mutation in complex with RK-59638 | | Descriptor: | Activin receptor type-1, N-(4-methoxyphenyl)-4-[3-(pyridin-3-yl)-1H-pyrazol-4-yl]pyrimidin-2-amine, SULFATE ION | | Authors: | Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. | | Deposit date: | 2018-07-27 | | Release date: | 2019-03-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Bis-Heteroaryl Pyrazoles: Identification of Orally Bioavailable Inhibitors of Activin Receptor-Like Kinase-2 (R206H).
Chem. Pharm. Bull., 67, 2019
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2YT8
 | | Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma) | | Descriptor: | Amyloid beta A4 precursor protein-binding family A member 3 | | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Seiki, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-04-05 | | Release date: | 2008-04-08 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma)
To be Published
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1UAN
 | | Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8 | | Descriptor: | hypothetical protein TT1542 | | Authors: | Handa, N, Terada, T, Tame, J.R.H, Park, S.-Y, Kinoshita, K, Ota, M, Nakamura, H, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-03-12 | | Release date: | 2003-08-05 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8
PROTEIN SCI., 12, 2003
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1UC9
 | | Crystal structure of a lysine biosynthesis enzyme, Lysx, from thermus thermophilus HB8 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, lysine biosynthesis enzyme | | Authors: | Sakai, H, Vassylyeva, M.N, Matsuura, T, Sekine, S, Nishiyama, M, Terada, T, Shirouzu, M, Kuramitsu, S, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-04-09 | | Release date: | 2003-09-23 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Crystal Structure of a Lysine Biosynthesis Enzyme, LysX, from Thermus thermophilus HB8
J.Mol.Biol., 332, 2003
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1UF3
 | | Crystal structure of TT1561 of thermus thermophilus HB8 | | Descriptor: | CALCIUM ION, hypothetical protein TT1561 | | Authors: | Kato-Murayama, M, Shirouzu, M, Terada, T, Murayama, K, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-05-23 | | Release date: | 2003-11-23 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of TT1561 of thermus thermophilus HB8
To be Published
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2YX8
 | | Crystal structure of the extracellular domain of human RAMP1 | | Descriptor: | Receptor activity-modifying protein 1 | | Authors: | Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Shindo, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-04-24 | | Release date: | 2008-04-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the human receptor activity-modifying protein 1 extracellular domain.
Protein Sci., 17, 2008
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1X4C
 | | Solution structure of RRM domain in splicing factor 2 | | Descriptor: | Splicing factor, arginine/serine-rich 1 | | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-14 | | Release date: | 2005-11-14 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of RRM domain in splicing factor 2
To be Published
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1WE6
 | | Solution structure of Ubiquitin-like domain in splicing factor AAL91182 | | Descriptor: | splicing factor, putative | | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-24 | | Release date: | 2004-11-24 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of Ubiquitin-like domain in splicing factor AAL91182
To be Published
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1WEW
 | | Solution structure of PHD domain in DNA-binding family protein AAM98074 | | Descriptor: | DNA-binding family protein, ZINC ION | | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-25 | | Release date: | 2004-11-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of PHD domain in DNA-binding family protein AAM98074
To be Published
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1WV9
 | | Crystal Structure of Rhodanese Homolog TT1651 from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 | | Descriptor: | Rhodanese Homolog TT1651 | | Authors: | Mizohata, E, Hattori, M, Tatsuguchi, A, Terada, T, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-12-12 | | Release date: | 2005-06-19 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the single-domain rhodanese homologue TTHA0613 from Thermus thermophilus HB8
Proteins, 64, 2006
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1WFX
 | | Crystal Structure of APE0204 from Aeropyrum pernix | | Descriptor: | CHLORIDE ION, Probable RNA 2'-phosphotransferase, ZINC ION | | Authors: | Kato-Murayama, M, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-27 | | Release date: | 2004-11-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure of the RNA 2'-Phosphotransferase from Aeropyrum pernix K1
J.Mol.Biol., 348, 2005
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1WHV
 | | Solution structure of the RNA binding domain from hypothetical protein BAB23382 | | Descriptor: | poly(A)-specific ribonuclease | | Authors: | Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-28 | | Release date: | 2004-11-28 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the RNA binding domain from hypothetical protein BAB23382
To be Published
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1WIA
 | | Solution structure of mouse hypothetical ubiquitin-like protein BAB25500 | | Descriptor: | hypothetical ubiquitin-like protein (RIKEN cDNA 2010008E23) | | Authors: | Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Hayashi, F, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-28 | | Release date: | 2004-11-28 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of mouse hypothetical ubiquitin-like protein BAB25500
To be Published
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1WD6
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1WEN
 | | Solution structure of PHD domain in ING1-like protein BAC25079 | | Descriptor: | ZINC ION, inhibitor of growth family, member 4; ING1-like protein | | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-25 | | Release date: | 2004-11-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of PHD domain in ING1-like protein BAC25079
To be Published
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1WF2
 | | Solution structure of RRM domain in HNRPC protein | | Descriptor: | Heterogeneous nuclear ribonucleoproteins C1/C2 | | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-25 | | Release date: | 2004-11-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of RRM domain in HNRPC protein
To be Published
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1WG4
 | | Solution structure of RRM domain in protein BAB31986 | | Descriptor: | HYPOTHETICAL PROTEIN (RIKEN cDNA 6030486K23) | | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-27 | | Release date: | 2004-11-27 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of RRM domain in protein BAB31986
To be Published
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1WHR
 | | Solution structure of the R3H domain from human hypothetical protein BAA76846 | | Descriptor: | Hypothetical KIAA1002 protein | | Authors: | Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-28 | | Release date: | 2004-11-28 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the R3H domain from human hypothetical protein BAA76846
To be Published
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1WEQ
 | | Solution structure of PHD domain in PHD finger protein 7 | | Descriptor: | PHD finger protein 7, ZINC ION | | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-25 | | Release date: | 2004-11-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of PHD domain in PHD finger protein 7
To be Published
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