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4MHJ
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BU of 4mhj by Molmil
Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin from A/goose/Guangdong/1/96 (H5N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H5M9 antibody, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-08-29
Release date:2013-10-02
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (6.98 Å)
Cite:A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013
6PBW
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BU of 6pbw by Molmil
Crystal structure of Fab667 complex
Descriptor: Fab667 heavy chain, Fab667 light chain, GLYCEROL, ...
Authors:Oyen, D, Wilson, I.A.
Deposit date:2019-06-14
Release date:2020-03-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.058 Å)
Cite:Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
3J5M
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BU of 3j5m by Molmil
Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs
Descriptor: BG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 heavy chain, ...
Authors:Lyumkis, D, Julien, J.-P, Wilson, I.A, Ward, A.B.
Deposit date:2013-10-26
Release date:2013-11-13
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
3KU5
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BU of 3ku5 by Molmil
Crystal structure of a H2N2 influenza virus hemagglutinin, human like
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2009-11-26
Release date:2010-01-19
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic.
J.Virol., 84, 2010
4L1S
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BU of 4l1s by Molmil
Covalent modification of transthyretin K15 by yielding the fluorescent conjugate (E)-3-(dimethylamino)-5-(4-hydroxy-3,5-dimethylstyryl)benzamide
Descriptor: S-(4-fluorophenyl) 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzenecarbothioate, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2013-06-03
Release date:2013-10-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Fluorogenic small molecules requiring reaction with a specific protein to create a fluorescent conjugate for biological imaging-what we know and what we need to learn.
Biopolymers, 101, 2014
6OO0
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BU of 6oo0 by Molmil
Crystal structure of bovine Fab NC-Cow1
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, NC-Cow1 heavy chain, NC-Cow1 light chain
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2019-04-22
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv, 6, 2020
4LG2
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BU of 4lg2 by Molmil
Crystal structure of Reston Ebola virus VP35 RNA binding domain bound to 12-bp dsRNA
Descriptor: Polymerase cofactor, dsRNA
Authors:Bale, S, Julien, J.-P, Bornholdt, Z.A, Krois, A.S, Wilson, I.A, Saphire, E.O.
Deposit date:2013-06-27
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism.
J.Virol., 87, 2013
4NUG
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BU of 4nug by Molmil
Crystal structure of HIV-1 broadly neutralizing antibody PGT151
Descriptor: HEXAETHYLENE GLYCOL, PGT151 heavy chain, PGT151 light chain
Authors:Blattner, C, Wilson, I.A.
Deposit date:2013-12-03
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8617 Å)
Cite:Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.
Immunity, 40, 2014
4NWU
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BU of 4nwu by Molmil
Crystal structure of APE1551, an anti-human NGF Fab with a nine amino acid insertion in CDR H1
Descriptor: APE1551 Ab Fab heavy chain, APE1551 Ab Fab light chain
Authors:Verdino, P, Stanfield, R.L, Wilson, I.A.
Deposit date:2013-12-06
Release date:2014-10-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies.
J.Biol.Chem., 289, 2014
6OC7
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BU of 6oc7 by Molmil
HMP42 Fab in complex with Protein G
Descriptor: Heavy chain of HMP42 Fab, Immunoglobulin G-binding protein G, Light chain for HMP42 Fab
Authors:Bernard, S.M, Wilson, I.A.
Deposit date:2019-03-22
Release date:2020-02-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.296 Å)
Cite:A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
6OPA
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BU of 6opa by Molmil
Crystal structure of bovine Fab NC-Cow1 in complex with HIV-1 BG505 SOSIP.664, and human Fabs 35022 and PGT128
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2019-04-24
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.084 Å)
Cite:Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv, 6, 2020
4NZR
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BU of 4nzr by Molmil
Crystal structure of the antibody-binding region of Protein M (Protein M TD) in complex with anti-HIV antibody PGT135 Fab
Descriptor: GLYCEROL, PGT135 heavy chain, PGT135 light chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-12-12
Release date:2014-02-19
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union.
Science, 343, 2014
4NZT
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BU of 4nzt by Molmil
Crystal structure of the antibody-binding region of Protein M (Protein M TD) in complex with anti-infleunza hemagglutinin antibody CR9114 Fab
Descriptor: CR9114 heavy chain, CR9114 light chain, Protein M TD
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-12-12
Release date:2014-02-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union.
Science, 343, 2014
6PBV
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BU of 6pbv by Molmil
Crystal structure of Fab668 complex
Descriptor: 1,2-ETHANEDIOL, Fab668 heavy chain, Fab668 light chain, ...
Authors:Oyen, D, Wilson, I.A.
Deposit date:2019-06-14
Release date:2020-03-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.566 Å)
Cite:Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
4NM8
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BU of 4nm8 by Molmil
Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8043, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-11-14
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.0041 Å)
Cite:A common solution to group 2 influenza virus neutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
4M5Z
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BU of 4m5z by Molmil
Crystal structure of broadly neutralizing antibody 5J8 bound to 2009 pandemic influenza hemagglutinin, HA1 subunit
Descriptor: Fab 5J8 heavy chain, Fab 5J8 light chain, Hemagglutinin HA1 chain
Authors:Hong, M, Lee, P.S, Wilson, I.A.
Deposit date:2013-08-08
Release date:2013-09-25
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site.
J.Virol., 87, 2013
6PZD
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BU of 6pzd by Molmil
Crystal structure of the neuraminidase stabilization mutant Y169aH from A/Shanghai/2/2013 (H7N9)
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2019-07-31
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6Q1Z
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BU of 6q1z by Molmil
Crystal structure of human 1G04 Fab in complex with influenza virus neuraminidase from A/Hunan/02650/2016 (H7N9)
Descriptor: 1G04 Fab IgG1 heavy chain, 1G04 Fab kappa light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2019-08-06
Release date:2019-10-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.446 Å)
Cite:Broadly protective human antibodies that target the active site of influenza virus neuraminidase.
Science, 366, 2019
4NM4
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BU of 4nm4 by Molmil
Crystal structure of broadly neutralizing antibody CR8043
Descriptor: Antibody CR8043, Heavy Chain, Light Chain, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-11-14
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A common solution to group 2 influenza virus neutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NUJ
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BU of 4nuj by Molmil
Crystal structure of HIV-1 broadly neutralizing antibody PGT152
Descriptor: PGT152 heavy chain, PGT152 light chain
Authors:Blattner, C, Wilson, I.A.
Deposit date:2013-12-03
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.827 Å)
Cite:Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.
Immunity, 40, 2014
4NZU
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BU of 4nzu by Molmil
Crystal structure of the primary monoclonal antibody 13PL Fab' from a multiple myeloma patient
Descriptor: 13PL heavy chain, 13PL light chain, ACETATE ION, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-12-12
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union.
Science, 343, 2014
4O58
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BU of 4o58 by Molmil
Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/3/1975 (H3N2) influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-12-19
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7501 Å)
Cite:Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
4M6K
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BU of 4m6k by Molmil
Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and folate
Descriptor: Dihydrofolate reductase, FOLIC ACID, GLYCEROL, ...
Authors:Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
Deposit date:2013-08-09
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.396 Å)
Cite:Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
4MHI
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BU of 4mhi by Molmil
Crystal structure of a H5N1 influenza virus hemagglutinin from A/goose/Guangdong/1/96
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-08-29
Release date:2013-10-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.595 Å)
Cite:A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013
4MHH
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BU of 4mhh by Molmil
Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin from A/Viet Nam/1203/2004 (H5N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H5M9 antibody, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-08-29
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.564 Å)
Cite:A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013

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數據於2024-10-16公開中

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