2NTF

Crystal Structure of a Quorum-Quenching Antibody in Complex with an N-Acyl-L-Homoserine Lactone Analog

Summary for 2NTF

• Entry DOI: 10.2210/pdb2ntf/pdb
• Descriptor: Murine Antibody Fab RS2-1G9 Lambda Light Chain, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, 3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE (3 entities in total)
• Functional Keywords: immunoglobulin, antibody, fab, hapten complex, quorum sensing, homoserine lactone, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 4
• Total formula weight: 94439.16

Authors

Debler, E.W.,Wilson, I.A. (deposition date: 2006-11-07, release date: 2007-05-08, Last modification date: 2023-08-30)

• Primary citation: Debler, E.W.,Kaufmann, G.F.,Kirchdoerfer, R.N.,Mee, J.M.,Janda, K.D.,Wilson, I.A.; Crystal Structures of a Quorum-quenching Antibody.; J.Mol.Biol., 368:1392-1402, 2007; PubMed: 17400249; DOI: 10.1016/j.jmb.2007.02.081

Experimental method

X-RAY DIFFRACTION (3.18 Å)