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6M62
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BU of 6m62 by Molmil
Cryo-Em structure of eukaryotic pre-60S ribosome subunit from Saccharomyces cerevisiae rpf2 delta 255-344 strain, C4 state.
Descriptor: 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
Authors:Li, Y, Micic, J.
Deposit date:2020-03-12
Release date:2020-08-26
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly.
Nat Commun, 11, 2020
6MHZ
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BU of 6mhz by Molmil
Vanadate trapped Cryo-EM Structure of E.coli LptB2FG Transporter
Descriptor: ADP ORTHOVANADATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ...
Authors:Orlando, B.J, Li, Y, Liao, M.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
6MI7
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BU of 6mi7 by Molmil
Nucleotide-free Cryo-EM Structure of E.coli LptB2FGC
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ...
Authors:Orlando, B.J, Li, Y, Liao, M.
Deposit date:2018-09-19
Release date:2019-04-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
7YFS
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BU of 7yfs by Molmil
The NMR structure of noursin, a tricyclic ribosomal peptide containing a histidine-to-butyrine crosslink
Descriptor: noursin
Authors:Yao, H, Li, Y, Zhang, T, Gao, J, Wang, H.
Deposit date:2022-07-09
Release date:2023-05-31
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Discovery and biosynthesis of tricyclic copper-binding ribosomal peptides containing histidine-to-butyrine crosslinks.
Nat Commun, 14, 2023
5W2J
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BU of 5w2j by Molmil
Crystal structure of dimeric form of mouse Glutaminase C
Descriptor: CHLORIDE ION, Glutaminase kidney isoform, mitochondrial, ...
Authors:Cerione, R.A, Li, Y.
Deposit date:2017-06-06
Release date:2018-10-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanistic Basis of Glutaminase Activation: A KEY ENZYME THAT PROMOTES GLUTAMINE METABOLISM IN CANCER CELLS.
J. Biol. Chem., 291, 2016
7XYW
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BU of 7xyw by Molmil
Crystal structure of ZYG11B bound to AFLH degron
Descriptor: Protein zyg-11 homolog B
Authors:Dong, C, Yan, X, Li, Y.
Deposit date:2022-06-02
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
7XYX
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BU of 7xyx by Molmil
Crystal structure of ZYG11B bound to CFLH degron
Descriptor: Protein zyg-11 homolog B
Authors:Dong, C, Yan, X, Li, Y.
Deposit date:2022-06-02
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
7XYS
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BU of 7xys by Molmil
Crystal structure of ZER1 bound to SFLH degron
Descriptor: Protein zer-1 homolog
Authors:Dong, C, Yan, X, Li, Y.
Deposit date:2022-06-02
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
7XYU
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BU of 7xyu by Molmil
Crystal structure of ZER1 bound to TFLH degron
Descriptor: Protein zer-1 homolog
Authors:Dong, C, Yan, X, Li, Y.
Deposit date:2022-06-02
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
7XYV
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BU of 7xyv by Molmil
Crystal structure of ZYG11B bound to SFLH degron
Descriptor: Protein zyg-11 homolog B
Authors:Dong, C, Yan, X, Li, Y.
Deposit date:2022-06-02
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
7BTB
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BU of 7btb by Molmil
Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.22 Angstroms resolution(state R2)
Descriptor: 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
Authors:Li, Y, Wilson, D.M.
Deposit date:2020-04-01
Release date:2020-10-28
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structural insights into assembly of the ribosomal nascent polypeptide exit tunnel.
Nat Commun, 11, 2020
7BT6
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BU of 7bt6 by Molmil
Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.12 Angstroms resolution(state R1)
Descriptor: 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
Authors:Li, Y, Wilson, D.M.
Deposit date:2020-03-31
Release date:2020-10-28
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural insights into assembly of the ribosomal nascent polypeptide exit tunnel.
Nat Commun, 11, 2020
7XRB
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BU of 7xrb by Molmil
human STK19 dimer
Descriptor: CHLORIDE ION, Isoform 2 of Serine/threonine-protein kinase 19, SULFATE ION
Authors:Sun, Q, Li, Y.
Deposit date:2022-05-10
Release date:2023-06-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:human STK19 dimer
To Be Published
1C6V
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BU of 1c6v by Molmil
SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H)
Descriptor: PROTEIN (SIU89134), PROTEIN (SIV INTEGRASE)
Authors:Chen, Z, Yan, Y, Munshi, S, Li, Y, Zruygay-Murphy, J, Xu, B, Witmer, M, Felock, P, Wolfe, A, Sardana, V, Emini, E.A, Hazuda, D, Kuo, L.C.
Deposit date:1999-12-21
Release date:2000-12-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.
J.Mol.Biol., 296, 2000
4KR0
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BU of 4kr0 by Molmil
Complex structure of MERS-CoV spike RBD bound to CD26
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ...
Authors:Lu, G, Hu, Y, Wang, Q, Qi, J, Gao, F, Li, Y, Zhang, Y, Zhang, W, Yuan, Y, Zhang, B, Shi, Y, Yan, J, Gao, G.F.
Deposit date:2013-05-15
Release date:2013-07-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.
Nature, 500, 2013
4KQZ
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BU of 4kqz by Molmil
structure of the receptor binding domain (RBD) of MERS-CoV spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, S protein
Authors:Lu, G, Hu, Y, Wang, Q, Qi, J, Gao, F, Li, Y, Zhang, Y, Zhang, W, Yuan, Y, Bao, J, Zhang, B, Shi, Y, Yan, J, Gao, G.F.
Deposit date:2013-05-15
Release date:2013-07-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.514 Å)
Cite:Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.
Nature, 500, 2013
8SSX
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BU of 8ssx by Molmil
Crystal structure of Bacillus anthracis dihydrofolate reductase at 1.65-A resolution
Descriptor: 1,2-ETHANEDIOL, Dihydrofolate reductase, SULFATE ION
Authors:Shaw, G.X, Li, Y, Wu, Y, Yan, H, Ji, X.
Deposit date:2023-05-09
Release date:2023-05-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of Bacillus anthracis dihydrofolate reductase at 1.65-A resolution
To be published
4WMH
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BU of 4wmh by Molmil
Structure of heme oxygenase-2 containing residues 1-288 lacking the membrane spanning region
Descriptor: CHLORIDE ION, Heme oxygenase 2
Authors:Bianchetti, C.M, Li, Y, Ragsdale, S.W, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2014-10-09
Release date:2014-11-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of heme oxygenase-2 containing residues 1-288 lacking the membrane spanning region
To Be Published
4TVR
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BU of 4tvr by Molmil
Tandem Tudor and PHD domains of UHRF2
Descriptor: E3 ubiquitin-protein ligase UHRF2, UNKNOWN ATOM OR ION, ZINC ION
Authors:Walker, J.R, Dong, A, Zhang, Q, Ong, M, Duan, S, Li, Y, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2014-06-27
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structure of the Tandem Tudor and PHD domains of UHRF2
To be published
5MV2
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BU of 5mv2 by Molmil
Crystal structure of the E protein of the Japanese encephalitis live attenuated vaccine virus
Descriptor: E protein
Authors:Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J.
Deposit date:2017-01-14
Release date:2018-05-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism.
Protein Cell, 10, 2019
5MV1
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BU of 5mv1 by Molmil
Crystal structure of the E protein of the Japanese encephalitis virulent virus
Descriptor: E protein
Authors:Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J.
Deposit date:2017-01-14
Release date:2018-05-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism.
Protein Cell, 10, 2019
1S1J
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BU of 1s1j by Molmil
Crystal Structure of ZipA in complex with indoloquinolizin inhibitor 1
Descriptor: (12bS)-1,2,3,4,12,12b-hexahydroindolo[2,3-a]quinolizin-7(6H)-one, Cell division protein zipA
Authors:Jenning, L.D, Foreman, K.W, Rush III, T.S, Tsao, D.H, Mosyak, L, Li, Y, Sukhdeo, M.N, Ding, W, Dushin, E.G, Kenney, C.H, Moghazeh, S.L, Peterson, P.J, Ruzin, A.V, Tuckman, M, Sutherland, A.G.
Deposit date:2004-01-06
Release date:2004-05-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction
Bioorg.Med.Chem.Lett., 14, 2004
1S1S
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BU of 1s1s by Molmil
Crystal Structure of ZipA in complex with indoloquinolizin 10b
Descriptor: Cell division protein zipA, N-{3-[(12bS)-7-oxo-1,3,4,6,7,12b-hexahydroindolo[2,3-a]quinolizin-12(2H)-yl]propyl}propane-2-sulfonamide
Authors:Jennings, L.D, Foreman, K.W, Rush III, T.S, Tsao, D.H, Mosyak, L, Li, Y, Sukhdeo, M.N, Ding, W, Dushin, E.G, Kenny, C.H, Moghazeh, S.L, Petersen, P.J, Ruzin, A.V, Tuckman, M, Sutherland, A.G.
Deposit date:2004-01-07
Release date:2005-01-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction
BIOORG.MED.CHEM.LETT., 14, 2004
1SBZ
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BU of 1sbz by Molmil
Crystal Structure of dodecameric FMN-dependent Ubix-like Decarboxylase from Escherichia coli O157:H7
Descriptor: FLAVIN MONONUCLEOTIDE, Probable aromatic acid decarboxylase
Authors:Rangarajan, E.S, Li, Y, Iannuzzi, P, Tocilj, A, Hung, L.-W, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2004-02-11
Release date:2004-10-26
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a dodecameric FMN-dependent UbiX-like decarboxylase (Pad1) from Escherichia coli O157: H7.
Protein Sci., 13, 2004
7YNX
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BU of 7ynx by Molmil
Crystal structure of Pirh2 bound to poly-Ala peptide
Descriptor: RING finger and CHY zinc finger domain-containing protein 1, SODIUM ION, SULFATE ION, ...
Authors:Dong, C, Yan, X, Li, Y.
Deposit date:2022-08-01
Release date:2023-04-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Recognition of an Ala-rich C-degron by the E3 ligase Pirh2.
Nat Commun, 14, 2023

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數據於2024-10-16公開中

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