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4NIE
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BU of 4nie by Molmil
Crystal structure of the orphan nuclear receptor ROR(gamma)t ligand-binding domain in complex with small molecule ligand
Descriptor: 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, N-(4-{[benzyl(propyl)amino]methyl}phenyl)-2-[4-(ethylsulfonyl)phenyl]acetamide, Nuclear receptor ROR-gamma, ...
Authors:Ma, Y.L, Yang, L.Q.
Deposit date:2013-11-06
Release date:2013-12-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Discovery of Tertiary Amine and Indole Derivatives as Potent ROR gamma t Inverse Agonists.
Acs Med.Chem.Lett., 5, 2014
7CH7
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BU of 7ch7 by Molmil
Cryo-EM structure of E.coli MlaFEB
Descriptor: Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, Phospholipid ABC transporter ATP-binding protein MlaF
Authors:Zhou, C, Shi, H, Huang, Y.
Deposit date:2020-07-05
Release date:2021-05-19
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa.
J.Mol.Biol., 433, 2021
7CHA
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BU of 7cha by Molmil
Cryo-EM structure of P.aeruginosa MlaFEBD with AMPPNP
Descriptor: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, MlaD domain-containing protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Zhou, C, Shi, H, Zhang, M, Huang, Y.
Deposit date:2020-07-05
Release date:2021-05-19
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa.
J.Mol.Biol., 433, 2021
7CH6
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BU of 7ch6 by Molmil
Cryo-EM structure of E.coli MlaFEB with AMPPNP
Descriptor: Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Zhou, C, Shi, H, Zhang, M, Huang, Y.
Deposit date:2020-07-05
Release date:2021-08-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa.
J.Mol.Biol., 433, 2021
7CH9
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BU of 7ch9 by Molmil
Cryo-EM structure of P.aeruginosa MlaFEBD
Descriptor: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, MlaD domain-containing protein, Probable ATP-binding component of ABC transporter, ...
Authors:Zhou, C, Shi, H, Zhang, M, Huang, Y.
Deposit date:2020-07-05
Release date:2021-10-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa.
J.Mol.Biol., 433, 2021
7CH8
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BU of 7ch8 by Molmil
Cryo-EM structure of P.aeruginosa MlaFEBD with ADP-V
Descriptor: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ADP METAVANADATE, MAGNESIUM ION, ...
Authors:Zhou, C, Shi, H, Zhang, M, Huang, Y.
Deposit date:2020-07-05
Release date:2021-10-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa.
J.Mol.Biol., 433, 2021
6LOX
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BU of 6lox by Molmil
Crystal Structure of human glutaminase with macrocyclic inhibitor
Descriptor: (E)-15,22-Dioxa-4,11-diaza-5(2,5)-thiadiazola-10(3,6)-pyridazina-1,14(1,3)-dibenzenacyclodocosaphan-18-ene-3,12-dione, Glutaminase kidney isoform, mitochondrial
Authors:Bian, J, Li, Z, Xu, X, Wang, J, Li, L.
Deposit date:2020-01-07
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure-Enabled Discovery of Novel Macrocyclic Inhibitors Targeting Glutaminase 1 Allosteric Binding Site.
J.Med.Chem., 64, 2021
7DEO
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BU of 7deo by Molmil
Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Spike protein S1, ...
Authors:Fu, D, Zhang, G, Li, X, Rao, Z, Guo, Y.
Deposit date:2020-11-04
Release date:2021-03-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
7DET
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BU of 7det by Molmil
Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv
Authors:Wang, Y, Zhang, G, Li, X, Rao, Z, Guo, Y.
Deposit date:2020-11-05
Release date:2021-03-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
7DEU
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BU of 7deu by Molmil
Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv
Authors:Zhang, Z, Zhang, G, Li, X, Rao, Z, Guo, Y.
Deposit date:2020-11-05
Release date:2021-03-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
6AKM
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BU of 6akm by Molmil
Crystal structure of SLMAP-SIKE1 complex
Descriptor: GLYCEROL, Sarcolemmal membrane-associated protein, Suppressor of IKBKE 1
Authors:Ma, J, Chen, M, Zhou, Z.C.
Deposit date:2018-09-02
Release date:2019-01-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019
4YNA
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BU of 4yna by Molmil
Oxidized YfiR
Descriptor: SULFATE ION, YfiR
Authors:Xu, M, Jiang, T.
Deposit date:2015-03-09
Release date:2015-04-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of YfiR from Pseudomonas aeruginosa in two redox states
Biochem.Biophys.Res.Commun., 461, 2015
4YN9
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BU of 4yn9 by Molmil
YfiR mutant-C110S
Descriptor: SULFATE ION, YfiR
Authors:Xu, M, Jiang, T.
Deposit date:2015-03-09
Release date:2015-04-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structures of YfiR from Pseudomonas aeruginosa in two redox states
Biochem.Biophys.Res.Commun., 461, 2015
7YFY
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BU of 7yfy by Molmil
Cryo-EM structure of the Mili-piRNA- target ternary complex
Descriptor: MAGNESIUM ION, Piwi-like protein 2, RNA (5'-R(P*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ...
Authors:Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z.
Deposit date:2022-07-09
Release date:2024-01-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
7YG6
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BU of 7yg6 by Molmil
Cryo-EM structure of the EfPiwi(N959K) in complex with piRNA
Descriptor: MAGNESIUM ION, Piwi, piRNA
Authors:Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z.
Deposit date:2022-07-11
Release date:2024-01-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
7YFX
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BU of 7yfx by Molmil
Cryo-EM structure of Hili in complex with piRNA
Descriptor: MAGNESIUM ION, Piwi-like protein 2, piRNA
Authors:Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z.
Deposit date:2022-07-09
Release date:2024-01-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
7YGN
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BU of 7ygn by Molmil
Cryo-EM structure of the Mili in complex with piRNA
Descriptor: MAGNESIUM ION, Piwi-like protein 2, piRNA
Authors:Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z.
Deposit date:2022-07-11
Release date:2024-01-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
7YFQ
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BU of 7yfq by Molmil
Cryo-EM structure of the EfPiwi (N959K)-piRNA-target ternary complex
Descriptor: MAGNESIUM ION, Piwi, RNA (5'-R(*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ...
Authors:Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z.
Deposit date:2022-07-08
Release date:2024-02-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
7YHK
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BU of 7yhk by Molmil
Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5
Descriptor: 12H5 heavy chain, 12H5 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zheng, Q, Li, S, Li, T, Xue, W, Sun, H.
Deposit date:2022-07-13
Release date:2022-08-17
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses.
Nat Commun, 13, 2022
3TTM
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BU of 3ttm by Molmil
Crystal structure of SpuD in complex with putrescine
Descriptor: 1,4-DIAMINOBUTANE, Polyamine transport protein
Authors:Wu, D.H, Lim, S.C, Song, H.W.
Deposit date:2011-09-15
Release date:2012-03-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis of Substrate Binding Specificity Revealed by the Crystal Structures of Polyamine Receptors SpuD and SpuE from Pseudomonas aeruginosa
J.Mol.Biol., 416, 2012
3TTN
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BU of 3ttn by Molmil
Crystal structures of polyamine receptors SpuD and SpuE from Pseudomonas aeruginosa
Descriptor: Polyamine transport protein, SPERMIDINE
Authors:Lim, S.C, Wu, D.H, Song, H.W.
Deposit date:2011-09-15
Release date:2012-03-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis of Substrate Binding Specificity Revealed by the Crystal Structures of Polyamine Receptors SpuD and SpuE from Pseudomonas aeruginosa
J.Mol.Biol., 416, 2012
3TTL
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BU of 3ttl by Molmil
Crystal structure of apo-SpuE
Descriptor: Polyamine transport protein
Authors:Wu, D.H, Lim, S.C, Song, H.W.
Deposit date:2011-09-14
Release date:2012-03-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Substrate Binding Specificity Revealed by the Crystal Structures of Polyamine Receptors SpuD and SpuE from Pseudomonas aeruginosa
J.Mol.Biol., 416, 2012
3TTK
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BU of 3ttk by Molmil
Crystal structure of apo-SpuD
Descriptor: Polyamine transport protein
Authors:Wu, D.H, Lim, S.C, Song, H.W.
Deposit date:2011-09-14
Release date:2012-03-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structural Basis of Substrate Binding Specificity Revealed by the Crystal Structures of Polyamine Receptors SpuD and SpuE from Pseudomonas aeruginosa
J.Mol.Biol., 416, 2012
3H42
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BU of 3h42 by Molmil
Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody
Descriptor: Fab from LDLR competitive antibody: Heavy chain, Fab from LDLR competitive antibody: Light chain, Proprotein convertase subtilisin/kexin type 9, ...
Authors:Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T, Tsai, M.M, Yang, E.
Deposit date:2009-04-17
Release date:2009-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Proc.Natl.Acad.Sci.USA, 106, 2009
7F3X
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BU of 7f3x by Molmil
Lysophospholipid acyltransferase LPCAT3 in complex with lysophosphatidylcholine
Descriptor: LPCAT3, [2-((1-OXODODECANOXY-(2-HYDROXY-3-PROPANYL))-PHOSPHONATE-OXY)-ETHYL]-TRIMETHYLAMMONIUM
Authors:Zhang, Q, Yao, D, Rao, B, Li, S, Jian, L, Chen, Y, Hu, K, Xia, Y, Shen, Y, Cao, Y.
Deposit date:2021-06-17
Release date:2021-12-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Nat Commun, 12, 2021

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數據於2024-07-24公開中

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