7YGN

Cryo-EM structure of the Mili in complex with piRNA

Summary for 7YGN

Entry DOI	10.2210/pdb7ygn/pdb
EMDB information	33817
Descriptor	Piwi-like protein 2, piRNA, MAGNESIUM ION (3 entities in total)
Functional Keywords	pirna, piwi protein, argonaute, rna binding protein, rna binding protein-rna complex, rna binding protein/rna
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	2
Total formula weight	100161.79
Authors	Li, Z.Q.,Liu, H.B.,Wu, J.P.,Shen, E.Z. (deposition date: 2022-07-11, release date: 2024-01-24, Last modification date: 2024-05-08)
Primary citation	Li, Z.,Li, Z.,Zhang, Y.,Zhou, L.,Xu, Q.,Li, L.,Zeng, L.,Xue, J.,Niu, H.,Zhong, J.,Yu, Q.,Li, D.,Gui, M.,Huang, Y.,Tu, S.,Zhang, Z.,Song, C.Q.,Wu, J.,Shen, E.Z. Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38658622 DOI: 10.1038/s41594-024-01287-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation