2K0Z
| Solution NMR structure of protein hp1203 from Helicobacter pylori 26695. Northeast Structural Genomics Consortium (NESG) target PT1/Ontario Center for Structural Proteomics target hp1203 | Descriptor: | Uncharacterized protein hp1203 | Authors: | Wu, B, Yee, A, Lemak, A, Cort, J, Semest, A, Kenney, M.A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-02-18 | Release date: | 2008-03-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of protein hp1203 from Helicobacter pylori 26695. Northeast Structural Genomics Consortium (NESG) target PT1/Ontario Center for Structural Proteomics target hp1203. To be Published
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3I91
| Crystal structure of human chromobox homolog 8 (CBX8) with H3K9 peptide | Descriptor: | Chromobox protein homolog 8, H3K9 peptide | Authors: | Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-07-10 | Release date: | 2009-09-08 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
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1YX3
| NMR structure of Allochromatium vinosum DsrC: Northeast Structural Genomics Consortium target OP4 | Descriptor: | hypothetical protein DsrC | Authors: | Cort, J.R, Dahl, C, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-02-19 | Release date: | 2005-04-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Allochromatium vinosum DsrC: solution-state NMR structure, redox properties, and interaction with DsrEFH, a protein essential for purple sulfur bacterial sulfur oxidation. J.Mol.Biol., 382, 2008
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3I90
| Crystal structure of human chromobox homolog 6 (CBX6) with H3K27 peptide | Descriptor: | Chromobox protein homolog 6, H3K27 peptide | Authors: | Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-07-10 | Release date: | 2009-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
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1ZBM
| X-Ray Crystal Structure of Protein AF1704 from Archaeoglobus fulgidus. Northeast Structural Genomics Consortium Target GR62A. | Descriptor: | hypothetical protein AF1704 | Authors: | Forouhar, F, Abashidze, M, Conover, K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-04-08 | Release date: | 2005-04-19 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: |
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1ZNO
| Crystal Structure of VC702 from Vibrio Cholerae, Northeast Structural Genomics Consortium Target: VcP1 | Descriptor: | Hypothetical UPF0244 protein VC0702, MAGNESIUM ION | Authors: | Ni, S, Forouhar, F, Bussiere, D.E, Robinson, H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-05-11 | Release date: | 2006-07-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of VC0702 at 2.0 A: conserved hypothetical protein from Vibrio cholerae. Proteins, 63, 2006
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4MEO
| Crystal Structure of the first bromodomain of human BRD4 in complex with a 2-methyl-quinoline ligand | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, DIMETHYL SULFOXIDE, ... | Authors: | Filippakopoulos, P, Picaud, S, Felletar, I, Martin, S, Fedorov, O, Vidler, L.R, Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Hoelder, S, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2013-08-27 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening. J.Med.Chem., 56, 2013
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3II7
| Crystal structure of the kelch domain of human KLHL7 | Descriptor: | 1,2-ETHANEDIOL, Kelch-like protein 7 | Authors: | Chaikuad, A, Thangaratnarajah, C, Cooper, C.D.O, Ugochukwu, E, Muniz, J.R.C, Krojer, T, Sethi, R, Pike, A.C.W, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC) | Deposit date: | 2009-07-31 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases. J.Biol.Chem., 288, 2013
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2KON
| NMR solution structure of CV_2116 from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CvT4(1-82) | Descriptor: | Uncharacterized protein | Authors: | Yang, Y, Ramelot, T.A, Cort, J.R, Garcia, M, Yee, A, Arrowsmith, C.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-09-24 | Release date: | 2009-10-13 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR solution structure of CV_2116 from Chromobacterium violaceum.Northeast Structural Genomics Consortium Target CvT4(1-82) To be Published
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1TVI
| Solution structure of TM1509 from Thermotoga maritima: VT1, a NESGC target protein | Descriptor: | Hypothetical UPF0054 protein TM1509 | Authors: | Penhoat, C.H, Atreya, H.S, Kim, S, Li, Z, Yee, A, Xiao, R, Murray, D, Arrowsmith, C.H, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-06-29 | Release date: | 2005-01-04 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR solution structure of Thermotoga maritima protein TM1509 reveals a Zn-metalloprotease-like tertiary structure. J.STRUCT.FUNCT.GENOM., 6, 2005
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2KL5
| Solution NMR Structure of protein yutD from B.subtilis, Northeast Structural Genomics Consortium Target SR232 | Descriptor: | Uncharacterized protein yutD | Authors: | Liu, G, Hamilton, K, Xiao, R, Ciccosanti, C, Ho, C.J, Everett, J, Nair, R, Acton, T, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-06-30 | Release date: | 2009-07-14 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of protein yutD from B.subtilis, Northeast Structural Genomics Consortium Target Target SR232 To be Published
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2KPW
| NMR solution structure of Lamin-B1 protein from Homo sapiens: Northeast Structural Genomics Consortium MEGA target, HR5546A (439-549) | Descriptor: | Lamin-B1 | Authors: | Swapna, G.V.T, Ciccosanti, C.L, Belote, R, Hamilton, K, Acton, T, Huang, Y, Xiao, R, Everett, J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-10-21 | Release date: | 2009-11-10 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR solution structure of Lamin-B1 protein from Homo sapiens: Northeast Structural Genomics Consortium target, HR5546A (439-549) To be Published
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3F4L
| Crystal structure of a probable oxidoreductase yhhX in Triclinic form. Northeast Structural Genomics target ER647 | Descriptor: | Putative oxidoreductase yhhX | Authors: | Seetharaman, J, Abashidze, M, Wang, H, Janjua, H, Foote, E.L, Xiao, R, Nair, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-10-31 | Release date: | 2008-11-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: |
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2KEY
| Solution NMR structure of a domain from a putative phage integrase protein BF2284 from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR257C | Descriptor: | Putative phage integrase | Authors: | Mills, J.L, Sathyamoorthy, B, Sukumaran, D.K, Lee, D, Ciccosanti, C, Jiang, M, Xiao, R, Acton, T.B, Swapna, G.V.T, Rost, B, Nair, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-02-06 | Release date: | 2009-04-14 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of a Domain from a Putative Phage Integrase Protein, BF2284, from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR257C To be Published
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1ZTS
| Solution Structure of Bacillus Subtilis Protein YQBG: Northeast Structural Genomics Consortium Target SR215 | Descriptor: | Hypothetical protein yqbG | Authors: | Liu, G, Shen, Y, Xiao, R, Acton, T, Ma, L, Joachimiak, A, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-05-27 | Release date: | 2005-07-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of protein yqbG from Bacillus subtilis reveals a novel alpha-helical protein fold. Proteins, 62, 2006
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2AFC
| X-Ray Crystal Structure of Protein Q8A8B0 from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium Target BtR9. | Descriptor: | conserved hypothetical protein | Authors: | Kuzin, A.P, Abashidze, M, Vorobiev, S.M, Acton, T, Xiao, R, Conover, K, Ma, L.-C, Cunninggham, K.E, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-07-25 | Release date: | 2005-08-02 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray structure of Q8A8B0 hypothetical protein from Bacteroides thetaiotaomicron To be Published
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3KHU
| Crystal structure of human UDP-glucose dehydrogenase Glu161Gln, in complex with thiohemiacetal intermediate | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, UDP-glucose 6-dehydrogenase, ... | Authors: | Chaikuad, A, Egger, S, Yue, W.W, Guo, K, Sethi, R, Filippakopoulos, P, Muniz, J.R.C, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Kavanagh, K.L, Nidetzky, B, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2009-10-30 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and Kinetic Evidence That Catalytic Reaction of Human UDP-glucose 6-Dehydrogenase Involves Covalent Thiohemiacetal and Thioester Enzyme Intermediates. J.Biol.Chem., 287, 2012
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3FAC
| Crystal structure of Rhodobacter sphaeroides protein RSP_2168. Northeast Structural Genomics target RhR83. | Descriptor: | Putative uncharacterized protein | Authors: | Seetharaman, J, Neely, H, Forouhar, F, Wang, H, Janjua, H, Foote, E.L, Xiao, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-11-16 | Release date: | 2008-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: |
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1XFS
| X-Ray Crystal Structure of Protein NE0264 from Nitrosomonas europaea. Northeast Structural Genomics Consortium Target NeR5. | Descriptor: | conserved hypothetical protein | Authors: | Forouhar, F, Abashidze, M, Vorobiev, S.M, Ciano, M, Ma, L.-C, Shastry, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-09-15 | Release date: | 2004-09-28 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of the hypothetical Protein from Nitrosomonas europaea, NESG Target NeR5 To be Published
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3JUV
| Crystal structure of human lanosterol 14alpha-demethylase (CYP51) | Descriptor: | Cycloheptakis-(1-4)-(alpha-D-glucopyranose), Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Strushkevich, N, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Usanov, S.A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-15 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | Structural basis of human CYP51 inhibition by antifungal azoles. J. Mol. Biol., 397, 2010
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2HFI
| Solution NMR Structure of Protein yppE from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR213 | Descriptor: | Hypothetical protein yppE | Authors: | Liu, G, Singarapu, K.K, Parish, D, Eletsky, A, Xu, D, Sukumaran, D, Ho, C.K, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-06-23 | Release date: | 2006-07-25 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of hypothetical protein yppE: Northeast Structural Genomics Consortium Target SR213 TO BE PUBLISHED
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2KW4
| Solution NMR Structure of the Holo Form of a Ribonuclease H domain from D.hafniense, Northeast Structural Genomics Consortium Target DhR1A | Descriptor: | MAGNESIUM ION, Uncharacterized protein | Authors: | Mills, J.L, Eletsky, A, Hua, J, Belote, R.L, Buchwald, W.A, Ciccosanti, C, Janjua, H, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-03-31 | Release date: | 2010-05-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Northeast Structural Genomics Consortium Target DhR1A To be Published
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2NW9
| Crystal Structure of Tryptophan 2,3-dioxygenase (TDO) from Xanthomonas campestris in complex with ferrous heme and 6-fluoro-tryptophan. Northeast Structural Genomics Target XcR13 | Descriptor: | 6-FLUORO-L-TRYPTOPHAN, MANGANESE (II) ION, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Forouhar, F, Anderson, J.L.R, Mowat, C.G, Bruckmann, C, Thackray, S.J, Seetharaman, J, Ho, C.K, Ma, L.C, Cunningham, K, Janjua, H, Zhao, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Champman, S.K, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-11-14 | Release date: | 2006-12-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase. Proc.Natl.Acad.Sci.Usa, 104, 2007
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3THT
| Crystal structure and RNA binding properties of the RRM/AlkB domains in human ABH8, an enzyme catalyzing tRNA hypermodification, Northeast Structural Genomics Consortium Target HR5601B | Descriptor: | 2-OXOGLUTARIC ACID, Alkylated DNA repair protein alkB homolog 8, MANGANESE (II) ION, ... | Authors: | Pastore, C, Topalidou, I, Forouhar, F, Yan, A.C, Levy, M, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-08-19 | Release date: | 2011-11-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification. J.Biol.Chem., 287, 2012
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2KW7
| Solution NMR Structure of the N-terminal domain of protein PG_0361 from P.gingivalis, Northeast Structural Genomics Consortium Target PgR37A | Descriptor: | Conserved domain protein | Authors: | Eletsky, A, Mills, J.L, Lee, D, Ciccosanti, C, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-03-31 | Release date: | 2010-04-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of the N-terminal domain of protein PG_0361 from P.gingivalis, Northeast Structural Genomics Consortium Target Target PgR37A To be Published
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