3THT
Crystal structure and RNA binding properties of the RRM/AlkB domains in human ABH8, an enzyme catalyzing tRNA hypermodification, Northeast Structural Genomics Consortium Target HR5601B
Summary for 3THT
Entry DOI | 10.2210/pdb3tht/pdb |
Related | 3THP |
Descriptor | Alkylated DNA repair protein alkB homolog 8, ZINC ION, MANGANESE (II) ION, ... (5 entities in total) |
Functional Keywords | structural genomics, psi-biology, northeast structural genomics consortium, nesg, alpha-beta two domain protein containing a zinc structure motif, trna modifying enzyme, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q96BT7 |
Total number of polymer chains | 4 |
Total formula weight | 158504.52 |
Authors | Pastore, C.,Topalidou, I.,Forouhar, F.,Yan, A.C.,Levy, M.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2011-08-19, release date: 2011-11-02, Last modification date: 2023-09-13) |
Primary citation | Pastore, C.,Topalidou, I.,Forouhar, F.,Yan, A.C.,Levy, M.,Hunt, J.F. Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification. J.Biol.Chem., 287:2130-2143, 2012 Cited by PubMed: 22065580DOI: 10.1074/jbc.M111.286187 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.01 Å) |
Structure validation
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