3II7

Crystal structure of the kelch domain of human KLHL7

Summary for 3II7

Entry DOI	10.2210/pdb3ii7/pdb
Descriptor	Kelch-like protein 7, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	protein-binding, kelch-repeat, structural genomics, structural genomics consortium, sgc, kelch repeat, nucleus, protein binding
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q8IXQ5
Total number of polymer chains	1
Total formula weight	35626.49
Authors	Chaikuad, A.,Thangaratnarajah, C.,Cooper, C.D.O.,Ugochukwu, E.,Muniz, J.R.C.,Krojer, T.,Sethi, R.,Pike, A.C.W.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Bullock, A.,Structural Genomics Consortium (SGC) (deposition date: 2009-07-31, release date: 2009-08-25, Last modification date: 2023-09-06)
Primary citation	Canning, P.,Cooper, C.D.,Krojer, T.,Murray, J.W.,Pike, A.C.,Chaikuad, A.,Keates, T.,Thangaratnarajah, C.,Hojzan, V.,Ayinampudi, V.,Marsden, B.D.,Gileadi, O.,Knapp, S.,von Delft, F.,Bullock, A.N. Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases. J.Biol.Chem., 288:7803-7814, 2013 Cited by PubMed: 23349464 DOI: 10.1074/jbc.M112.437996 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.63 Å)

Structure validation