Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO A 951 |
| Chain | Residue |
| A | GLY300 |
| A | EDO953 |
| A | SER301 |
| A | GLN302 |
| A | SER305 |
| A | CYS306 |
| A | ILE319 |
| A | ARG320 |
| A | CYS321 |
| A | HOH939 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 952 |
| Chain | Residue |
| A | ARG320 |
| A | ASP360 |
| A | TRP362 |
| A | HOH616 |
| A | HOH617 |
| A | HOH678 |
| A | EDO965 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 953 |
| Chain | Residue |
| A | PRO303 |
| A | GLN304 |
| A | ASP318 |
| A | EDO951 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 954 |
| Chain | Residue |
| A | ARG307 |
| A | TRP316 |
| A | ALA563 |
| A | PHE564 |
| A | EDO975 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 955 |
| Chain | Residue |
| A | VAL426 |
| A | VAL477 |
| A | PHE478 |
| A | ALA524 |
| A | ALA525 |
| A | HOH758 |
| A | HOH775 |
| A | HOH929 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 956 |
| Chain | Residue |
| A | PHE298 |
| A | LYS325 |
| A | ARG326 |
| A | HOH625 |
| A | HOH823 |
| A | EDO957 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE EDO A 957 |
| Chain | Residue |
| A | ARG326 |
| A | ARG327 |
| A | ASP328 |
| A | ALA329 |
| A | LYS522 |
| A | SER568 |
| A | CYS569 |
| A | LEU570 |
| A | HOH760 |
| A | HOH868 |
| A | EDO956 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 958 |
| Chain | Residue |
| A | THR520 |
| A | LYS522 |
| A | PHE536 |
| A | THR567 |
| A | SER568 |
| A | HOH746 |
| A | HOH860 |
| A | HOH924 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 959 |
| Chain | Residue |
| A | LEU505 |
| A | TRP516 |
| A | LYS517 |
| A | GLN537 |
| A | HOH844 |
| A | HOH849 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 960 |
| Chain | Residue |
| A | GLY494 |
| A | VAL519 |
| A | GLN537 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 961 |
| Chain | Residue |
| A | ARG446 |
| A | VAL447 |
| A | ASN490 |
| A | GLY491 |
| A | HOH741 |
| A | HOH865 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 962 |
| Chain | Residue |
| A | GLY300 |
| A | SER301 |
| A | GLN302 |
| A | GLU324 |
| A | LYS325 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 963 |
| Chain | Residue |
| A | PRO565 |
| A | VAL566 |
| A | THR567 |
| A | SER568 |
| A | HOH806 |
| A | HOH922 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 964 |
| Chain | Residue |
| A | PRO322 |
| A | ILE349 |
| A | LYS350 |
| A | EDO966 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 966 |
| Chain | Residue |
| A | GLU324 |
| A | GLN345 |
| A | LEU346 |
| A | PHE347 |
| A | PRO348 |
| A | HOH889 |
| A | EDO964 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 967 |
| Chain | Residue |
| A | SER415 |
| A | HOH704 |
| A | EDO973 |
| A | LEU397 |
| A | TYR398 |
| A | LEU399 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 965 |
| Chain | Residue |
| A | LYS365 |
| A | LEU366 |
| A | EDO952 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 968 |
| Chain | Residue |
| A | GLU381 |
| A | ASP455 |
| A | HIS544 |
| A | ARG562 |
| A | HOH799 |
| A | HOH894 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 969 |
| Chain | Residue |
| A | LYS290 |
| A | TYR398 |
| A | SER415 |
| A | MET416 |
| A | LEU417 |
| site_id | CC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 970 |
| Chain | Residue |
| A | ASP496 |
| A | LYS504 |
| A | PRO513 |
| A | HOH645 |
| A | HOH705 |
| A | HOH716 |
| A | HOH764 |
| A | HOH909 |
| site_id | CC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 971 |
| Chain | Residue |
| A | LYS480 |
| A | LYS482 |
| A | LEU492 |
| A | THR550 |
| A | GLU551 |
| A | HOH640 |
| A | HOH659 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 972 |
| Chain | Residue |
| A | GLU547 |
| A | ASN549 |
| A | LYS554 |
| A | VAL556 |
| A | HOH665 |
| A | HOH717 |
| site_id | CC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 973 |
| Chain | Residue |
| A | ASP292 |
| A | ARG294 |
| A | ASN394 |
| A | ALA396 |
| A | TYR398 |
| A | GLN419 |
| A | HOH691 |
| A | EDO967 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 975 |
| Chain | Residue |
| A | TRP316 |
| A | VAL561 |
| A | ARG562 |
| A | HOH620 |
| A | HOH646 |
| A | EDO954 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 974 |
| Chain | Residue |
| A | PRO515 |
| A | VAL556 |
| A | ALA557 |
| A | HOH881 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"Kelch 1"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 2"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 47 |
| Details | Repeat: {"description":"Kelch 3"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 50 |
| Details | Repeat: {"description":"Kelch 4"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 5"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 6"} |
