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2O6L
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BU of 2o6l by Molmil
Crystal Structure of the UDP-Glucuronic Acid Binding Domain of the Human Drug Metabolizing UDP-Glucuronosyltransferase 2B7
Descriptor: UDP-glucuronosyltransferase 2B7
Authors:Miley, M.J, Redinbo, M.R.
Deposit date:2006-12-07
Release date:2007-05-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7.
J.Mol.Biol., 369, 2007
6HTF
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BU of 6htf by Molmil
Crystal structure of human Btk SH2 domain bound to rF10 repebody
Descriptor: Tyrosine-protein kinase BTK, rF10 repebody
Authors:Duarte, D.P, Pojer, F, Hantschel, O.
Deposit date:2018-10-04
Release date:2020-05-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms.
Nat Commun, 11, 2020
2LOU
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BU of 2lou by Molmil
AR55 solubilised in DPC micelles
Descriptor: Apelin receptor
Authors:Langelaan, D.N, Rainey, J.K.
Deposit date:2012-01-27
Release date:2013-01-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural features of the apelin receptor N-terminal tail and first transmembrane segment implicated in ligand binding and receptor trafficking.
Biochim.Biophys.Acta, 1828, 2013
4L00
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BU of 4l00 by Molmil
Crystal structure of the apo Jak1 pseudokinase domain
Descriptor: Tyrosine-protein kinase JAK1
Authors:Toms, A.V, Eck, M.J.
Deposit date:2013-05-30
Release date:2013-09-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases.
Nat.Struct.Mol.Biol., 20, 2013
4L01
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BU of 4l01 by Molmil
Crystal structure of the V658F apo Jak1 pseudokinase domain
Descriptor: Tyrosine-protein kinase JAK1
Authors:Toms, A.V, Rogers, J.M, Eck, M.J.
Deposit date:2013-05-30
Release date:2013-09-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases.
Nat.Struct.Mol.Biol., 20, 2013
3FPD
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BU of 3fpd by Molmil
G9a-like protein lysine methyltransferase inhibition by BIX-01294
Descriptor: Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine, ...
Authors:Chang, Y, Zhang, X, Horton, J.R, Cheng, X.
Deposit date:2009-01-05
Release date:2009-02-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294.
Nat.Struct.Mol.Biol., 16, 2009
4RBU
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BU of 4rbu by Molmil
PduA K26A S40Q mutant, from Salmonella enterica serovar Typhimurium LT2
Descriptor: Propanediol utilization protein PduA, SULFATE ION
Authors:Chun, S, Sawaya, M.R, Yeates, T.O.
Deposit date:2014-09-13
Release date:2015-02-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Selective molecular transport through the protein shell of a bacterial microcompartment organelle.
Proc.Natl.Acad.Sci.USA, 112, 2015
4RFW
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BU of 4rfw by Molmil
Crystal structure of human retinoid X Receptor alpha-ligand binding domain complex with 9cUAB70 and the coactivator peptide GRIP-1
Descriptor: (2E,4E,6Z,8E)-3,7-dimethyl-8-(6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ylidene)octa-2,4,6-trienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha
Authors:Xia, G, Muccio, D.D, Smith, C.D.
Deposit date:2014-09-28
Release date:2015-09-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers.
J.Med.Chem., 58, 2015
4RME
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BU of 4rme by Molmil
Crystal structure of human Retinoid X receptor alpha ligand binding domain complex with 9cUAB111 and coactivator peptide GRIP-1
Descriptor: (2E,4E,6Z,8E)-3,7-dimethyl-8-[2-(3-methylbutyl)-3-(propan-2-yl)cyclohex-2-en-1-ylidene]octa-2,4,6-trienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha
Authors:Xia, G, Muccio, D.D.
Deposit date:2014-10-21
Release date:2015-09-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers.
J.Med.Chem., 58, 2015
4RBT
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BU of 4rbt by Molmil
PduA K26A S40L mutant, from Salmonella enterica serovar Typhimurium LT2
Descriptor: Propanediol utilization protein PduA, SULFATE ION
Authors:Chun, S, Sawaya, M.R, Yeates, T.O.
Deposit date:2014-09-12
Release date:2015-02-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Selective molecular transport through the protein shell of a bacterial microcompartment organelle.
Proc.Natl.Acad.Sci.USA, 112, 2015
4RMD
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BU of 4rmd by Molmil
Crystal structure of human Retinoid X receptor alpha ligand binding domain complex with 9cUAB110 and coactivator peptide GRIP-1
Descriptor: (2E,4E,6Z,8E)-8-[3-cyclopropyl-2-(3-methylbutyl)cyclohex-2-en-1-ylidene]-3,7-dimethylocta-2,4,6-trienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha
Authors:Xia, G, Muccio, D.D.
Deposit date:2014-10-21
Release date:2015-09-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers.
J.Med.Chem., 58, 2015
3HUP
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BU of 3hup by Molmil
High-resolution structure of the extracellular domain of human CD69
Descriptor: CHLORIDE ION, Early activation antigen CD69, SODIUM ION
Authors:Kolenko, P, Dohnalek, J, Skalova, T, Hasek, J, Duskova, J, Vanek, O, Bezouska, K.
Deposit date:2009-06-15
Release date:2009-12-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.371 Å)
Cite:The high-resolution structure of the extracellular domain of human CD69 using a novel polymer
Acta Crystallogr.,Sect.F, 65, 2009
4RMC
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BU of 4rmc by Molmil
Crystal Structure of human retinoid X receptor alpha-ligand binding domain complex with 9cUAB76 and the coactivator peptide GRIP-1
Descriptor: (3S,7S,8E)-8-[3-ethyl-2-(3-methylbutyl)cyclohex-2-en-1-ylidene]-3,7-dimethyloctanoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha
Authors:Xia, G, Muccio, D.D.
Deposit date:2014-10-21
Release date:2015-09-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers.
J.Med.Chem., 58, 2015
4RBV
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BU of 4rbv by Molmil
PduA K26A S40GSG mutant, from Salmonella enterica serovar Typhimurium LT2
Descriptor: Propanediol utilization protein PduA, SULFATE ION
Authors:Chun, S, Sawaya, M.R, Yeates, T.O.
Deposit date:2014-09-13
Release date:2015-02-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Selective molecular transport through the protein shell of a bacterial microcompartment organelle.
Proc.Natl.Acad.Sci.USA, 112, 2015
3LQM
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BU of 3lqm by Molmil
Structure of the IL-10R2 Common Chain
Descriptor: GLYCEROL, Interleukin-10 receptor subunit beta, SULFATE ION
Authors:Yoon, S.I, Walter, M.R.
Deposit date:2010-02-09
Release date:2010-05-26
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structure and mechanism of receptor sharing by the IL-10R2 common chain.
Structure, 18, 2010
3O52
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BU of 3o52 by Molmil
Structure of the E.coli GDP-mannose hydrolase (yffh) in complex with tartrate
Descriptor: CHLORIDE ION, D(-)-TARTARIC ACID, GDP-mannose pyrophosphatase nudK, ...
Authors:Amzel, L.M, Gabelli, S.B, Boto, A.N.
Deposit date:2010-07-27
Release date:2011-05-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition.
Proteins, 79, 2011
3O6Z
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BU of 3o6z by Molmil
Structure of the D152A E.coli GDP-mannose hydrolase (yffh) in complex with Mg++
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Amzel, L.M, Gabelli, S.B, Boto, A.N.
Deposit date:2010-07-29
Release date:2011-05-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition.
Proteins, 79, 2011
3O61
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BU of 3o61 by Molmil
Structure of the E100A E.coli GDP-mannose hydrolase (yffh) in complex with GDP-mannose and Mg++
Descriptor: CHLORIDE ION, GDP-mannose pyrophosphatase nudK, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, ...
Authors:Amzel, L.M, Gabelli, S.B, Boto, A.N.
Deposit date:2010-07-28
Release date:2011-05-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition.
Proteins, 79, 2011
3O69
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BU of 3o69 by Molmil
Structure of the E100A E.coli GDP-mannose hydrolase (yffh) in complex with Mg++
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GDP-mannose pyrophosphatase nudK, ...
Authors:Amzel, L.M, Gabelli, S.B, Boto, A.N.
Deposit date:2010-07-28
Release date:2011-05-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition.
Proteins, 79, 2011
6E7G
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BU of 6e7g by Molmil
Crystal structure of H5 hemagglutinin mutant Y161A from A/Viet Nam/1203/2004 H5N1 influenza virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Tzarum, N, Wilson, I.A.
Deposit date:2018-07-26
Release date:2019-06-19
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.094 Å)
Cite:N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses.
Cell Rep, 27, 2019
6E7H
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BU of 6e7h by Molmil
Crystal structure of H5 hemagglutinin mutant Y161A from A/Viet Nam/1203/2004 H5N1 influenza virus in complex with 3'-GcLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Tzarum, N, Wilson, I.A.
Deposit date:2018-07-26
Release date:2019-06-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses.
Cell Rep, 27, 2019
7TB0
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BU of 7tb0 by Molmil
E. faecium MurAA in complex with fosfomycin and UNAG
Descriptor: CHLORIDE ION, POTASSIUM ION, SODIUM ION, ...
Authors:Zhou, Y, Shamoo, Y.
Deposit date:2021-12-21
Release date:2022-12-28
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Enolpyruvate transferase MurAA A149E , identified during adaptation of Enterococcus faecium to daptomycin, increases stability of MurAA-MurG interaction.
J.Biol.Chem., 299, 2023
7TMA
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BU of 7tma by Molmil
Porous framework formed by assembly of a bipyridyl-conjugated helical peptide
Descriptor: ACETONITRILE, bipyridyl-conjugated helical peptide
Authors:Nguyen, A.I.
Deposit date:2022-01-19
Release date:2023-01-25
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (1 Å)
Cite:Assembly of pi-Stacking Helical Peptides into a Porous and Multivariable Proteomimetic Framework.
J.Am.Chem.Soc., 144, 2022
7TME
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BU of 7tme by Molmil
Porous framework formed by assembly of a bipyridyl-conjugated helical peptide
Descriptor: ACETONITRILE, bipyridyl-conjugated helical peptide
Authors:Nguyen, A.I.
Deposit date:2022-01-19
Release date:2023-01-25
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (0.8 Å)
Cite:Assembly of pi-Stacking Helical Peptides into a Porous and Multivariable Proteomimetic Framework.
J.Am.Chem.Soc., 144, 2022
7TLT
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BU of 7tlt by Molmil
SARS-CoV-2 Spike-derived peptide S489-497 (YFPLQSYGF) presented by HLA-A*29:02
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ...
Authors:Murdolo, L.D, Szeto, C, Gras, S.
Deposit date:2022-01-18
Release date:2022-10-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Ablation of CD8 + T cell recognition of an immunodominant epitope in SARS-CoV-2 Omicron variants BA.1, BA.2 and BA.3.
Nat Commun, 13, 2022

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數據於2024-11-13公開中

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