Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4L00

Crystal structure of the apo Jak1 pseudokinase domain

Summary for 4L00
Entry DOI10.2210/pdb4l00/pdb
Related4L01
DescriptorTyrosine-protein kinase JAK1 (2 entities in total)
Functional Keywordskinase domain fold, regulatory, transferase
Biological sourceHomo sapiens (human)
Cellular locationEndomembrane system; Peripheral membrane protein: P23458
Total number of polymer chains2
Total formula weight69836.23
Authors
Toms, A.V.,Eck, M.J. (deposition date: 2013-05-30, release date: 2013-09-04, Last modification date: 2024-02-28)
Primary citationToms, A.V.,Deshpande, A.,McNally, R.,Jeong, Y.,Rogers, J.M.,Kim, C.U.,Gruner, S.M.,Ficarro, S.B.,Marto, J.A.,Sattler, M.,Griffin, J.D.,Eck, M.J.
Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases.
Nat.Struct.Mol.Biol., 20:1221-1223, 2013
Cited by
PubMed: 24013208
DOI: 10.1038/nsmb.2673
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon