8Q5H
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![BU of 8q5h by Molmil](/molmil-images/mine/8q5h) | Human KMN network (outer kinetochore) | Descriptor: | Kinetochore protein Spc24, Kinetochore protein Spc25, Kinetochore scaffold 1, ... | Authors: | Raisch, T, Polley, S, Vetter, I, Musacchio, A, Raunser, S. | Deposit date: | 2023-08-09 | Release date: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Insights into human outer kinetochore assembly and force transmission from a structure-function analysis of the KMN network To Be Published
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5T4R
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![BU of 5t4r by Molmil](/molmil-images/mine/5t4r) | |
1A12
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![BU of 1a12 by Molmil](/molmil-images/mine/1a12) | REGULATOR OF CHROMOSOME CONDENSATION (RCC1) OF HUMAN | Descriptor: | REGULATOR OF CHROMOSOME CONDENSATION 1 | Authors: | Renault, L, Nassar, N, Vetter, I, Becker, J, Roth, M, Wittinghofer, A. | Deposit date: | 1997-12-19 | Release date: | 1999-01-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller. Nature, 392, 1998
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4JHP
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![BU of 4jhp by Molmil](/molmil-images/mine/4jhp) | The crystal structure of the RPGR RCC1-like domain in complex with PDE6D | Descriptor: | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, X-linked retinitis pigmentosa GTPase regulator | Authors: | Waetzlich, D, Vetter, I, Wittinghofer, A, Ismail, S. | Deposit date: | 2013-03-05 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The interplay between RPGR, PDE-delta and Arl2/3 regulate the ciliary targeting of farnesylated cargo. Embo Rep., 14, 2013
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4JHN
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![BU of 4jhn by Molmil](/molmil-images/mine/4jhn) | The crystal structure of the RPGR RCC1-like domain | Descriptor: | X-linked retinitis pigmentosa GTPase regulator | Authors: | Waetzlich, D, Vetter, I, Wittinghofer, A, Ismail, S. | Deposit date: | 2013-03-05 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The interplay between RPGR, PDE-delta and Arl2/3 regulate the ciliary targeting of farnesylated cargo. Embo Rep., 14, 2013
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7R6P
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![BU of 7r6p by Molmil](/molmil-images/mine/7r6p) | |
8UXR
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![BU of 8uxr by Molmil](/molmil-images/mine/8uxr) | TxVIIB,U-superfamily conotoxin | Descriptor: | Conotoxin Tx6.5 | Authors: | Raffaelli, T, Daly, N. | Deposit date: | 2023-11-09 | Release date: | 2024-03-27 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural analysis of a U-superfamily conotoxin containing a mini-granulin fold: Insights into key features that distinguish between the ICK and granulin folds. J.Biol.Chem., 300, 2024
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8FD4
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![BU of 8fd4 by Molmil](/molmil-images/mine/8fd4) | |
8FEY
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![BU of 8fey by Molmil](/molmil-images/mine/8fey) | Solution structure of Pmu1a | Descriptor: | Pmu1a toxin | Authors: | Daly, N.L, Wilson, D.T. | Deposit date: | 2022-12-07 | Release date: | 2023-03-29 | Last modified: | 2023-08-02 | Method: | SOLUTION NMR | Cite: | Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNa V 1.7 and hCa V 3 voltage-gated channels. Febs J., 290, 2023
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7JPM
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![BU of 7jpm by Molmil](/molmil-images/mine/7jpm) | |
6VH8
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![BU of 6vh8 by Molmil](/molmil-images/mine/6vh8) | |
8JZM
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![BU of 8jzm by Molmil](/molmil-images/mine/8jzm) | The inhibitor of Toll-like receptor signaling o-vanillin binds covalently to MAL/TIRAP Lys-210 | Descriptor: | Toll/interleukin-1 receptor domain-containing adapter protein | Authors: | Rahaman, M.H, Jia, X, Maxwell, M.J, Mobli, M, Kobe, B. | Deposit date: | 2023-07-05 | Release date: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2. J Enzyme Inhib Med Chem, 39, 2024
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6WQR
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![BU of 6wqr by Molmil](/molmil-images/mine/6wqr) | |
5T3M
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4LFT
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![BU of 4lft by Molmil](/molmil-images/mine/4lft) | Structure of alpha-elapitoxin-Dpp2d isolated from Black Mamba (Dendroaspis polylepis) venom | Descriptor: | Alpha-elapitoxin-Dpp2a | Authors: | Wang, C.I.A, Reeks, T, Lewis, R.J, Alewood, P.F, Durek, T. | Deposit date: | 2013-06-27 | Release date: | 2014-06-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Isolation and Structural and Pharmacological Characterization of alpha-Elapitoxin-Dpp2d, an Amidated Three Finger Toxin from Black Mamba Venom. Biochemistry, 53, 2014
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7SAV
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![BU of 7sav by Molmil](/molmil-images/mine/7sav) | Native mu-conotoxin KIIIA isomer | Descriptor: | Mu-conotoxin KIIIA | Authors: | Schroeder, C.I, Tran, H.N.T. | Deposit date: | 2021-09-23 | Release date: | 2022-05-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural and functional insights into the inhibition of human voltage-gated sodium channels by mu-conotoxin KIIIA disulfide isomers. J.Biol.Chem., 298, 2022
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7RZ3
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![BU of 7rz3 by Molmil](/molmil-images/mine/7rz3) | |
7S7P
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![BU of 7s7p by Molmil](/molmil-images/mine/7s7p) | |
7SAW
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![BU of 7saw by Molmil](/molmil-images/mine/7saw) | Mu-conotoxin KIIIA isomer 2 | Descriptor: | Mu-conotoxin KIIIA | Authors: | Schroeder, C.I, Tran, H.N.T. | Deposit date: | 2021-09-23 | Release date: | 2022-05-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural and functional insights into the inhibition of human voltage-gated sodium channels by mu-conotoxin KIIIA disulfide isomers. J.Biol.Chem., 298, 2022
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4GOJ
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![BU of 4goj by Molmil](/molmil-images/mine/4goj) | The Crystal Structure of full length Arl3GppNHp in complex with UNC119a | Descriptor: | ADP-ribosylation factor-like protein 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Ismail, S, Xiang-Chen, Y, Miertzschke, M, Vetter, I, Koerner, C, Wittinghofer, A. | Deposit date: | 2012-08-20 | Release date: | 2012-09-19 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119. Embo J., 31, 2012
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4GOK
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![BU of 4gok by Molmil](/molmil-images/mine/4gok) | The Crystal structure of Arl2GppNHp in complex with UNC119a | Descriptor: | ADP-ribosylation factor-like protein 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Ismail, S, Xiang-Chen, Y, Miertzschke, M, Vetter, I, Koerner, C, Wittinghofer, A. | Deposit date: | 2012-08-20 | Release date: | 2012-09-19 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119. Embo J., 31, 2012
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6PPC
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![BU of 6ppc by Molmil](/molmil-images/mine/6ppc) | Solution structure of conotoxin MiXXVIIA | Descriptor: | Conopeptide phi-MiXXVIIA | Authors: | Daly, N.L, Dekan, Z, Jin, A.H, Alewood, P.F. | Deposit date: | 2019-07-06 | Release date: | 2019-08-14 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Conotoxin phi-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity. Angew. Chem. Int. Ed. Engl., 56, 2017
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6CEG
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6BL9
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![BU of 6bl9 by Molmil](/molmil-images/mine/6bl9) | |
6CUC
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![BU of 6cuc by Molmil](/molmil-images/mine/6cuc) | |