4JHP

The crystal structure of the RPGR RCC1-like domain in complex with PDE6D

Summary for 4JHP

• Entry DOI: 10.2210/pdb4jhp/pdb
• Related: 4JHN
• Descriptor: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, X-linked retinitis pigmentosa GTPase regulator (3 entities in total)
• Functional Keywords: immunoglobulin-like beta-sandwich, rcc1-like domain, beta propellar, seven bladed-propeller, structural protein, lipid binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytoskeleton, flagellum axoneme (By similarity). Isoform 6: Cytoplasm, cytoskeleton, centrosome: Q92834
• Total number of polymer chains: 2
• Total formula weight: 60125.95

Authors

Waetzlich, D.,Vetter, I.,Wittinghofer, A.,Ismail, S. (deposition date: 2013-03-05, release date: 2013-04-17, Last modification date: 2023-09-20)

• Primary citation: Watzlich, D.,Vetter, I.,Gotthardt, K.,Miertzschke, M.,Chen, Y.X.,Wittinghofer, A.,Ismail, S.; The interplay between RPGR, PDE-delta and Arl2/3 regulate the ciliary targeting of farnesylated cargo.; Embo Rep., 14:465-472, 2013; PubMed: 23559067; DOI: 10.1038/embor.2013.37

Experimental method

X-RAY DIFFRACTION (1.9 Å)