4JHP
The crystal structure of the RPGR RCC1-like domain in complex with PDE6D
Summary for 4JHP
Entry DOI | 10.2210/pdb4jhp/pdb |
Related | 4JHN |
Descriptor | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, X-linked retinitis pigmentosa GTPase regulator (3 entities in total) |
Functional Keywords | immunoglobulin-like beta-sandwich, rcc1-like domain, beta propellar, seven bladed-propeller, structural protein, lipid binding protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton, flagellum axoneme (By similarity). Isoform 6: Cytoplasm, cytoskeleton, centrosome: Q92834 |
Total number of polymer chains | 2 |
Total formula weight | 60125.95 |
Authors | Waetzlich, D.,Vetter, I.,Wittinghofer, A.,Ismail, S. (deposition date: 2013-03-05, release date: 2013-04-17, Last modification date: 2023-09-20) |
Primary citation | Watzlich, D.,Vetter, I.,Gotthardt, K.,Miertzschke, M.,Chen, Y.X.,Wittinghofer, A.,Ismail, S. The interplay between RPGR, PDE-delta and Arl2/3 regulate the ciliary targeting of farnesylated cargo. Embo Rep., 14:465-472, 2013 Cited by PubMed: 23559067DOI: 10.1038/embor.2013.37 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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