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8E1F
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BU of 8e1f by Molmil
Sterile Alpha Motif Domain of Human Translocation ETS Leukemia, Non-Polymer Crystal Form
Descriptor: CHLORIDE ION, MAGNESIUM ION, SULFATE ION, ...
Authors:Wilson, E, Nawarathnage, S, Stewart, C, Brown, S, Bezzant, B, Bunn, D, Towne, N, Pedroza Romo, M.J, Moody, J.D.
Deposit date:2022-08-10
Release date:2022-09-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Sterile Alpha Motif Domain of Human Translocation ETS Leukemia, Non-Polymer Crystal Form
To Be Published
7N2B
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BU of 7n2b by Molmil
A DARPin semi-rigidly fused to the 3TEL crystallization chaperone
Descriptor: Transcription factor ETV6,Transcription factor ETV6,Transcription factor ETV6,3TEL-rigid-DARPin
Authors:Sarath Nawarathange, S.D, Gajjar, P, Bunn, D, Stewart, C, Doukov, T, Moody, J.D.
Deposit date:2021-05-28
Release date:2021-06-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.221 Å)
Cite:Crystals of TELSAM-target protein fusions that exhibit minimal crystal contacts and lack direct inter-TELSAM contacts.
Open Biology, 12, 2022
7TDY
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BU of 7tdy by Molmil
The ubiquitin-associated domain of human thirty-eight negative kinase 1, flexibly fused to the 1TEL crystallization chaperone via a 2-glycine linker and crystallized at low protein concentration
Descriptor: FORMIC ACID, Transcription factor ETV6,Non-receptor tyrosine-protein kinase TNK1
Authors:Nawarathnage, S, Bunn, D.R, Stewart, C, Doukev, T, Moody, J.D.
Deposit date:2022-01-03
Release date:2023-01-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1 UBA domain.
Structure, 31, 2023
7TCY
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BU of 7tcy by Molmil
The ubiquitin-associated domain of human thirty-eight negative kinase I
Descriptor: CHLORIDE ION, FORMIC ACID, MAGNESIUM ION, ...
Authors:Nawarathnage, S, Bunn, R.D, Stewart, C, Doukov, T, Moody, J.D.
Deposit date:2021-12-29
Release date:2023-01-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1 UBA domain.
Structure, 31, 2023
7U4W
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BU of 7u4w by Molmil
The ubiquitin-associated domain of human thirty-eight negative kinase-1 flexibly fused to the 1TEL crystallization chaperone via a 2-glycine linker and crystallized at traditional protein concentration
Descriptor: Transcription factor ETV6,Non-receptor tyrosine-protein kinase TNK1
Authors:Nawarathnage, S, Pedroza Romo, M.J, Smith, T, Bunn, D, Stewart, C, Doukov, T, Moody, J.D.
Deposit date:2022-03-01
Release date:2023-03-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1 UBA domain.
Structure, 31, 2023
5W8Q
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BU of 5w8q by Molmil
Crystal structure of biphenyl synthase from Malus domestica
Descriptor: (3R)-butane-1,3-diol, BIS3 biphenyl synthase
Authors:Stewart Jr, C.E, Noel, J.P.
Deposit date:2017-06-22
Release date:2017-12-13
Method:X-RAY DIFFRACTION (1.173 Å)
Cite:Molecular architectures of benzoic acid-specific type III polyketide synthases.
Acta Crystallogr D Struct Biol, 73, 2017
5WC4
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BU of 5wc4 by Molmil
Crystal structure of biphenyl synthase from Malus domestic complexed with benzoyl-CoA
Descriptor: (3R)-butane-1,3-diol, BIS3 biphenyl synthase, benzoyl coenzyme A
Authors:Stewart Jr, C.E, Noel, J.P.
Deposit date:2017-06-29
Release date:2017-12-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Molecular architectures of benzoic acid-specific type III polyketide synthases.
Acta Crystallogr D Struct Biol, 73, 2017
5UCO
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BU of 5uco by Molmil
Benzophenone synthase from Hypericum androsaemum
Descriptor: 2,4,6-trihydroxybenzophenone synthase
Authors:Stewart Jr, C.E, Noel, J.P.
Deposit date:2016-12-22
Release date:2017-12-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Molecular architectures of benzoic acid-specific type III polyketide synthases.
Acta Crystallogr D Struct Biol, 73, 2017
5UC5
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BU of 5uc5 by Molmil
Chalcone synthase from Malus domestica
Descriptor: CHS2 chalcone synthase
Authors:Stewart Jr, C.E, Noel, J.P.
Deposit date:2016-12-21
Release date:2017-12-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Molecular architectures of benzoic acid-specific type III polyketide synthases.
Acta Crystallogr D Struct Biol, 73, 2017
8S9G
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BU of 8s9g by Molmil
SARS-CoV-2 BN.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Fab Heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-03-28
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neutralization, effector function and immune imprinting of Omicron variants.
Nature, 621, 2023
8VQ9
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BU of 8vq9 by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8VQB
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BU of 8vqb by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8VQA
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BU of 8vqa by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8FT8
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BU of 8ft8 by Molmil
The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Thr-Val linker variant, SUMO tag-free preparation
Descriptor: CHLORIDE ION, GLYCEROL, POTASSIUM ION, ...
Authors:Gajjar, P.L, Litchfield, C.M, Callahan, M, Redd, N, Doukov, T, Moody, J.D.
Deposit date:2023-01-11
Release date:2023-03-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Increasing the bulk of the 1TEL-target linker and retaining the 10×His tag in a 1TEL-CMG2-vWa construct improves crystal order and diffraction limits.
Acta Crystallogr D Struct Biol, 79, 2023
8FZU
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BU of 8fzu by Molmil
The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Thr-Val linker variant, Expressed with SUMO tag
Descriptor: POTASSIUM ION, SULFATE ION, Transcription factor ETV6,Anthrax toxin receptor 2
Authors:Gajjar, P.L, Litchfield, C.M, Callahan, M, Redd, N, Doukov, T, Lebedev, A, Moody, J.D.
Deposit date:2023-01-30
Release date:2023-07-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Increasing the bulk of the 1TEL-target linker and retaining the 10×His tag in a 1TEL-CMG2-vWa construct improves crystal order and diffraction limits.
Acta Crystallogr D Struct Biol, 79, 2023
8FZV
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BU of 8fzv by Molmil
The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Ala-Ala linker variant, expressed with SUMO tag
Descriptor: MAGNESIUM ION, Transcription factor ETV6,Anthrax toxin receptor 2, UNKNOWN ATOM OR ION
Authors:Pedroza Romo, M.J, Soleimani, S, Doukov, T, Lebedev, A, Moody, J.D.
Deposit date:2023-01-30
Release date:2023-07-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Increasing the bulk of the 1TEL-target linker and retaining the 10×His tag in a 1TEL-CMG2-vWa construct improves crystal order and diffraction limits.
Acta Crystallogr D Struct Biol, 79, 2023
8FT6
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BU of 8ft6 by Molmil
The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Ala-Ala linker variant, SUMO tag-free preparation.
Descriptor: CITRIC ACID, IODIDE ION, SULFATE ION, ...
Authors:Gajjar, P.L, Litchfield, C.M, Callahan, M, Redd, N, Doukov, T, Moody, J.D.
Deposit date:2023-01-11
Release date:2023-03-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Increasing the bulk of the 1TEL-target linker and retaining the 10×His tag in a 1TEL-CMG2-vWa construct improves crystal order and diffraction limits.
Acta Crystallogr D Struct Biol, 79, 2023
8FXB
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BU of 8fxb by Molmil
SARS-CoV-2 XBB.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-01-24
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Neutralization, effector function and immune imprinting of Omicron variants.
Nature, 621, 2023
8FXC
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BU of 8fxc by Molmil
SARS-CoV-2 BQ.1.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-01-24
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Neutralization, effector function and immune imprinting of Omicron variants.
Nature, 621, 2023
8ERQ
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BU of 8erq by Molmil
SARS-CoV-2 BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment (local refinement of the RBD and S2X324)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 Fab heavy chain, S2X324 Fab light chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-10-12
Release date:2022-10-26
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Science, 378, 2022
8ERR
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BU of 8err by Molmil
SARS-CoV-2 Omicron BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-10-12
Release date:2022-10-26
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Science, 378, 2022
8U0T
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BU of 8u0t by Molmil
PRD-0038 RBD bound to Rhinolophus alcyone ACE2 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, PRD-0038, ...
Authors:Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-08-29
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Cell Host Microbe, 31, 2023
8U29
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BU of 8u29 by Molmil
Prefusion structure of the PRD-0038 spike glycoprotein ectodomain trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRD-0038 Spike glycoprotein, ...
Authors:Lee, J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-05
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Cell Host Microbe, 31, 2023
8VGT
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BU of 8vgt by Molmil
Structure of the HKU1 RBD bound to the human TMPRSS2 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-12-27
Release date:2024-03-06
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Human coronavirus HKU1 recognition of the TMPRSS2 host receptor.
Cell, 2024
8DYA
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BU of 8dya by Molmil
Structure of the SARS-CoV-2 spike glycoprotein S2 subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-08-03
Release date:2022-11-30
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines.
Sci Immunol, 7, 2022

 

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