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8FT6

The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Ala-Ala linker variant, SUMO tag-free preparation.

Summary for 8FT6
Entry DOI10.2210/pdb8ft6/pdb
Related8E1F 8FT8 8FZ3 8FZ4
DescriptorTranscription factor ETV6,Anthrax toxin receptor 2 chimera, CITRIC ACID, IODIDE ION, ... (5 entities in total)
Functional Keywordstelsam fusion, polymer forming crystallization chaperone, peptide binding protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains1
Total formula weight30514.09
Authors
Gajjar, P.L.,Litchfield, C.M.,Callahan, M.,Redd, N.,Doukov, T.,Moody, J.D. (deposition date: 2023-01-11, release date: 2023-03-22, Last modification date: 2023-10-18)
Primary citationGajjar, P.L.,Pedroza Romo, M.J.,Litchfield, C.M.,Callahan, M.,Redd, N.,Nawarathnage, S.,Soleimani, S.,Averett, J.,Wilson, E.,Lewis, A.,Stewart, C.,Tseng, Y.J.,Doukov, T.,Lebedev, A.,Moody, J.D.
Increasing the bulk of the 1TEL-target linker and retaining the 10×His tag in a 1TEL-CMG2-vWa construct improves crystal order and diffraction limits.
Acta Crystallogr D Struct Biol, 79:925-943, 2023
Cited by
PubMed: 37747038
DOI: 10.1107/S2059798323007246
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.62 Å)
Structure validation

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