8FT6

The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Ala-Ala linker variant, SUMO tag-free preparation.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Transcription factor ETV6,Anthrax toxin receptor 2 chimera	polymer	266	29972.1	1	UniProt (P41212) UniProt (P58335) Pfam (PF02198) Pfam (PF00092)	Homo sapiens (human)	ETS translocation variant 6,ETS-related protein Tel1,Tel,Capillary morphogenesis gene 2 protein,CMG-2
2	B (A)	CITRIC ACID	non-polymer		192.1	1	Chemie (CIT)
3	C, D (A)	IODIDE ION	non-polymer		126.9	2	Chemie (IOD)
4	E (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5	F (A)	water	water		18.0	32	Chemie (HOH)

Sequence modifications

A: 12 - 89 (UniProt: P41212)

PDB	External Database	Details
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
Ala 14	Arg 49	engineered mutation
Glu 77	Val 112	engineered mutation
Ala 87	Lys 122	engineered mutation
Ala 89	Arg 124	engineered mutation

A: 90 - 267 (UniProt: P58335)

PDB	External Database	Details
Ala 91	Arg 41	engineered mutation
Ala 225	Cys 175	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29972.1
Non-Polymers*	Number of molecules	4
	Total formula weight	542.0
All*	Total formula weight	30514.1

*Water molecules are not included.