8FZU

The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Thr-Val linker variant, Expressed with SUMO tag

Summary for 8FZU

Entry DOI	10.2210/pdb8fzu/pdb
Related	8E1F 8FZ3 8FZ4 8FZ6 8FZ8
Descriptor	Transcription factor ETV6,Anthrax toxin receptor 2, POTASSIUM ION, SULFATE ION, ... (4 entities in total)
Functional Keywords	telsam fusion, polymer forming crystallization chaperone, peptide binding protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	86252.46
Authors	Gajjar, P.L.,Litchfield, C.M.,Callahan, M.,Redd, N.,Doukov, T.,Lebedev, A.,Moody, J.D. (deposition date: 2023-01-30, release date: 2023-07-19, Last modification date: 2023-10-18)
Primary citation	Gajjar, P.L.,Pedroza Romo, M.J.,Litchfield, C.M.,Callahan, M.,Redd, N.,Nawarathnage, S.,Soleimani, S.,Averett, J.,Wilson, E.,Lewis, A.,Stewart, C.,Tseng, Y.J.,Doukov, T.,Lebedev, A.,Moody, J.D. Increasing the bulk of the 1TEL-target linker and retaining the 10×His tag in a 1TEL-CMG2-vWa construct improves crystal order and diffraction limits. Acta Crystallogr D Struct Biol, 79:925-943, 2023 Cited by PubMed: 37747038 DOI: 10.1107/S2059798323007246 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation