8FZU
The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Thr-Val linker variant, Expressed with SUMO tag
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Transcription factor ETV6,Anthrax toxin receptor 2 | polymer | 257 | 28705.8 | 3 | UniProt (P41212) UniProt (P58335) Pfam (PF02198) Pfam (PF00092) | Homo sapiens (human) | ETS translocation variant 6,ETS-related protein Tel1,Tel,Capillary morphogenesis gene 2 protein,CMG-2 |
| 2 | D (B) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 3 | E (C) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G, H (A, B, C) | water | water | 18.0 | 827 | Chemie (HOH) |
Sequence modifications
A, B, C: 2 - 66 (UniProt: P41212)
A, B, C: 79 - 257 (UniProt: P58335)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ala 4 | Arg 49 | conflict |
| Glu 67 | - | linker |
| Leu 68 | - | linker |
| Tyr 69 | - | linker |
| Glu 70 | - | linker |
| Leu 71 | - | linker |
| Leu 72 | - | linker |
| Gln 73 | - | linker |
| His 74 | - | linker |
| Ile 75 | - | linker |
| Leu 76 | - | linker |
| Ala 77 | - | linker |
| Gln 78 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 79 | Cys 39 | conflict |
| Thr 81 | Arg 41 | engineered mutation |
| Val 82 | Ala 42 | engineered mutation |
| Ala 215 | Cys 175 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 86117.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 135.2 | |
| All* | Total formula weight | 86252.5 |
