8FT8

The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Thr-Val linker variant, SUMO tag-free preparation

Summary for 8FT8

Entry DOI	10.2210/pdb8ft8/pdb
Related	8E1F 8FT6 8FZ3 8FZ4
Descriptor	Transcription factor ETV6,Anthrax toxin receptor 2 chimera, GLYCEROL, CHLORIDE ION, ... (6 entities in total)
Functional Keywords	telsam fusion, polymer forming crystallization chaperone, peptide binding protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	1
Total formula weight	30363.79
Authors	Gajjar, P.L.,Litchfield, C.M.,Callahan, M.,Redd, N.,Doukov, T.,Moody, J.D. (deposition date: 2023-01-11, release date: 2023-03-01, Last modification date: 2023-10-25)
Primary citation	Gajjar, P.L.,Pedroza Romo, M.J.,Litchfield, C.M.,Callahan, M.,Redd, N.,Nawarathnage, S.,Soleimani, S.,Averett, J.,Wilson, E.,Lewis, A.,Stewart, C.,Tseng, Y.J.,Doukov, T.,Lebedev, A.,Moody, J.D. Increasing the bulk of the 1TEL-target linker and retaining the 10×His tag in a 1TEL-CMG2-vWa construct improves crystal order and diffraction limits. Acta Crystallogr D Struct Biol, 79:925-943, 2023 Cited by PubMed: 37747038 DOI: 10.1107/S2059798323007246 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation