8FT8
The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Thr-Val linker variant, SUMO tag-free preparation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Transcription factor ETV6,Anthrax toxin receptor 2 chimera | polymer | 266 | 30030.2 | 1 | UniProt (P41212) UniProt (P58335) Pfam (PF02198) Pfam (PF00092) In PDB | Homo sapiens (human) | ETS translocation variant 6,ETS-related protein Tel1,Tel,Capillary morphogenesis gene 2 protein,CMG-2 |
2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
3 | A | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
4 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
5 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
6 | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A: 12 - 89 (UniProt: P41212)
A: 90 - 267 (UniProt: P58335)
PDB | External Database | Details |
---|---|---|
His 2 | - | expression tag |
His 3 | - | expression tag |
His 4 | - | expression tag |
His 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
His 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
His 11 | - | expression tag |
Ala 14 | Arg 49 | engineered mutation |
Glu 77 | Val 112 | engineered mutation |
Ala 87 | Lys 122 | engineered mutation |
Ala 89 | Arg 124 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Thr 91 | Arg 41 | engineered mutation |
Val 92 | Ala 42 | engineered mutation |
Ala 225 | Cys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 30030.2 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 333.6 | |
All* | Total formula weight | 30363.8 |