8FT8

The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Thr-Val linker variant, SUMO tag-free preparation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Transcription factor ETV6,Anthrax toxin receptor 2 chimera	polymer	266	30030.2	1	UniProt (P41212) UniProt (P58335) Pfam (PF02198) Pfam (PF00092)	Homo sapiens (human)	ETS translocation variant 6,ETS-related protein Tel1,Tel,Capillary morphogenesis gene 2 protein,CMG-2
2	B (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
3	C, D, E (A)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
4	F (A)	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
5	G (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
6	H (A)	water	water		18.0	144	Chemie (HOH)

Sequence modifications

A: 12 - 89 (UniProt: P41212)

PDB	External Database	Details
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
Ala 14	Arg 49	engineered mutation
Glu 77	Val 112	engineered mutation
Ala 87	Lys 122	engineered mutation
Ala 89	Arg 124	engineered mutation

A: 90 - 267 (UniProt: P58335)

PDB	External Database	Details
Thr 91	Arg 41	engineered mutation
Val 92	Ala 42	engineered mutation
Ala 225	Cys 175	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	30030.2
Non-Polymers*	Number of molecules	6
	Total formula weight	333.6
All*	Total formula weight	30363.8

*Water molecules are not included.