4L69
 
 | |
3KJZ
 
 | Crystal structure of native peptidyl-tRNA hydrolase from Mycobacterium smegmatis | Descriptor: | Peptidyl-tRNA hydrolase | Authors: | Kumar, A, Singh, N, Yadav, R, Prem Kumar, R, Sharma, S, Arora, A, Singh, T.P. | Deposit date: | 2009-11-04 | Release date: | 2010-08-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of peptidyl-tRNA hydrolase from mycobacterium smegmatis reveals novel features related to enzyme dynamics. Int J Biochem Mol Biol, 3, 2012
|
|
8BR4
 
 | Structure of GAPDH from Mycobacterium tuberculosis | Descriptor: | 1,2-ETHANEDIOL, Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Kumar, A, Karthikeyan, S. | Deposit date: | 2022-11-22 | Release date: | 2023-11-01 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Stoichiometry of ligand binding and role of C-terminal lysines in Mycobacterium tuberculosis and human GAPDH multifunctionality. Febs J., 2024
|
|
9ERK
 
 | |
9ERI
 
 | |
9ERJ
 
 | |
9ERL
 
 | |
4LQ6
 
 | Crystal structure of Rv3717 reveals a novel amidase from M. tuberculosis | Descriptor: | CHLORIDE ION, N-acetymuramyl-L-alanine amidase-related protein, PLATINUM (II) ION, ... | Authors: | Kumar, A, Kumar, S, Kumar, D, Mishra, A, Dewangan, R.P, Shrivastava, P, Ramachandran, S, Taneja, B. | Deposit date: | 2013-07-17 | Release date: | 2013-12-04 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | The structure of Rv3717 reveals a novel amidase from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 69, 2013
|
|
2RKW
 
 | Intermediate position of ATP on its trail to the binding pocket inside the subunit B mutant R416W of the energy converter A1Ao ATP synthase | Descriptor: | V-type ATP synthase beta chain | Authors: | Kumar, A, Manimekalai, M.S.S, Balakrishna, A.M, Hunke, C, Gruber, G. | Deposit date: | 2007-10-18 | Release date: | 2008-09-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Spectroscopic and crystallographic studies of the mutant R416W give insight into the nucleotide binding traits of subunit B of the A1Ao ATP synthase Proteins, 75, 2009
|
|
5Y06
 
 | |
5Y05
 
 | |
8BW0
 
 | Structure of CEACAM5 A3-B3 domain in Complex with Tusamitamab Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Carcinoembryonic antigen-related cell adhesion molecule 5, ... | Authors: | Kumar, A, Bertrand, T, Rapisarda, C, Rak, A. | Deposit date: | 2022-12-06 | Release date: | 2024-01-24 | Last modified: | 2024-11-13 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Structural insights into epitope-paratope interactions of a monoclonal antibody targeting CEACAM5-expressing tumors. Nat Commun, 15, 2024
|
|
6Y90
 
 | Structure of full-length CD20 in complex with Rituximab Fab | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, B-lymphocyte antigen CD20, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Kumar, A, Reyes, N. | Deposit date: | 2020-03-06 | Release date: | 2020-08-26 | Last modified: | 2025-04-09 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Binding mechanisms of therapeutic antibodies to human CD20. Science, 369, 2020
|
|
6Y97
 
 | |
6Y92
 
 | |
6Y9A
 
 | |
8C4A
 
 | |
6JQV
 
 | Crystal structure of Arabidopsis thaliana NRP2 | Descriptor: | NAP1-related protein 2 | Authors: | Kumar, A, Vasudevan, D. | Deposit date: | 2019-04-01 | Release date: | 2019-07-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Structural Characterization ofArabidopsis thalianaNAP1-Related Protein 2 (AtNRP2) and Comparison with its Homolog AtNRP1. Molecules, 24, 2019
|
|
5N74
 
 | Microtubule end binding protein complex | Descriptor: | Karyogamy protein KAR9, Microtubule-associated protein RP/EB family member 1 | Authors: | Kumar, A, Steinmetz, M. | Deposit date: | 2017-02-18 | Release date: | 2017-06-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Short Linear Sequence Motif LxxPTPh Targets Diverse Proteins to Growing Microtubule Ends. Structure, 25, 2017
|
|
5N38
 
 | S65DParkin and pUB complex | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, ... | Authors: | Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H. | Deposit date: | 2017-02-08 | Release date: | 2017-04-19 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity. Nat. Struct. Mol. Biol., 24, 2017
|
|
5N2W
 
 | WT-Parkin and pUB complex | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ... | Authors: | Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H. | Deposit date: | 2017-02-08 | Release date: | 2017-04-19 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity. Nat. Struct. Mol. Biol., 24, 2017
|
|
1JYM
 
 | Crystals of Peptide Deformylase from Plasmodium falciparum with Ten Subunits per Asymmetric Unit Reveal Critical Characteristics of the Active Site for Drug Design | Descriptor: | COBALT (II) ION, Peptide Deformylase | Authors: | Kumar, A, Nguyen, K.T, Srivathsan, S, Ornstein, B, Turley, S, Hirsh, I, Pei, D, Hol, W.G.J. | Deposit date: | 2001-09-12 | Release date: | 2002-03-13 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystals of peptide deformylase from Plasmodium falciparum reveal critical characteristics of the active site for drug design. Structure, 10, 2002
|
|
3KK0
 
 | Crystal structure of partially folded intermediate state of peptidyl-tRNA hydrolase from Mycobacterium smegmatis | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Kumar, A, Singh, N, Yadav, R, Sharma, S, Arora, A, Singh, T.P. | Deposit date: | 2009-11-04 | Release date: | 2010-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structures of Fully-Folded Native and Partially-Folded Intermediate States of Peptidyl-tRNA Hydrolase from Mycobacterium smegmatis To be Published
|
|
7AG9
 
 | |
5OAT
 
 | PINK1 structure | Descriptor: | MAGNESIUM ION, Serine/threonine-protein kinase PINK1, mitochondrial-like Protein | Authors: | Kumar, A, Tamjar, J, Woodroof, H.I, Raimi, O.G, Waddell, A.Y, Peggie, M, Muqit, M.M.K, van Aalten, D.M.F. | Deposit date: | 2017-06-23 | Release date: | 2017-10-11 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Structure of PINK1 and mechanisms of Parkinson's disease associated mutations. Elife, 6, 2017
|
|